Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Gerald A. Meininger"'
Autor:
Zahra Nourian, Kwangseok Hong, Min Li, Jorge A. Castorena-Gonzalez, Luis A. Martinez-Lemus, Philip S. Clifford, Gerald A. Meininger, Michael A. Hill
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Vascular extracellular matrix (ECM) is dominated by elastic fibers (elastin with fibrillin-rich microfibrils) and collagens. Current understanding of ECM protein development largely comes from studies of conduit vessels (e.g., aorta) wh
Externí odkaz:
https://doaj.org/article/6d8b2f396a4049b7bff826333ab77c6f
Autor:
Yan Yang, Zahra Nourian, Min Li, Zhe Sun, Liping Zhang, Michael J. Davis, Gerald A. Meininger, Jianbo Wu, Andrew P. Braun, Michael A. Hill
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Fibronectin (FN) enhances K+ channel activity by integrin-mediated mechanisms. As vascular smooth muscle (VSM) K+ channels mediate vasodilation, we hypothesized that modification of fibronectin, via advanced non-enzymatic glycation, would alter signa
Externí odkaz:
https://doaj.org/article/0bb74b71c4f74c80a4b4302c11030a73
Autor:
Leike Xie, Zhe Sun, Nicola J. Brown, Olga V. Glinskii, Gerald A. Meininger, Vladislav V. Glinsky
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Cancer cell adhesion to the endothelium is a crucial process in hematogenous metastasis, but how the integrity of the endothelial barrier and endothelial cell (EC) mechanical properties influence the adhesion between metastatic cancer cells and the e
Externí odkaz:
https://doaj.org/article/d3c9e676fd304e82b5af093122d1f5e0
Autor:
Gerald A. Meininger, Michael A. Hill
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/56bf24a377124eaa82ed9414c122b568
A Calcium Mediated Mechanism Coordinating Vascular Smooth Muscle Cell Adhesion During KCl Activation
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Efficient mechanotransduction in vascular smooth muscle cells (VSMCs) is intimately coupled to physical coupling of the cell to extracellular matrix proteins (ECM) by integrins. Integrin adhesion receptors are essential for normal vascular function a
Externí odkaz:
https://doaj.org/article/e3a6c3b562864a56bf66ccc0ea14a1a1
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 12, Pp 23792-23835 (2014)
The microcirculation is a portion of the vascular circulatory system that consists of resistance arteries, arterioles, capillaries and venules. It is the place where gases and nutrients are exchanged between blood and tissues. In addition the microci
Externí odkaz:
https://doaj.org/article/caeeabff2ba24f518f66a0c8de654706
Publikováno v:
Central Asian Journal of Global Health, Vol 3, Iss 0 (2014)
Introduction: Alzheimer’s disease (AD) is a chronic neurodegenerative disorder, which affects approximately 10% of the population aged 65 and 40% of people over the age 80. Currently, AD is on the list of diseases with no effective treatment. Thus,
Externí odkaz:
https://doaj.org/article/cb7dd6e6250c4949b2da53dc031ffb64
Autor:
Marius C. Staiculescu, Francisco I. Ramirez-Perez, Jorge A. Castorena-Gonzalez, Zhongkui eHong, Zhe eSun, Gerald A. Meininger, Luis A. Martinez-Lemus
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
In vascular smooth muscle cells (VSMC) increased integrin adhesion to extracellular matrix (ECM) proteins, as well as the production of reactive oxygen species (ROS) are strongly stimulated by lysophosphatidic acid (LPA). We hypothesized that LPA-ind
Externí odkaz:
https://doaj.org/article/e68e073a162f4a9aa3215f3330acc666
Ventricular remodeling is one of the primary adaptive mechanisms in response to long-term mechanical overload in diabetes. In addition to cardiomyocyte hypertrophy, alterations in noncardiomyocyte compartments [e.g. extracellular matrix (ECM)] are an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa97270b5ae5eb549b92adb0edef74d3
https://doi.org/10.1101/2022.11.15.516690
https://doi.org/10.1101/2022.11.15.516690
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)