Safety and efficacy of inhaled interferon-β1a (SNG001) in adults with mild-to-moderate COVID-19: a randomized, controlled, phase II trialResearch in context

Autor: Prasanna Jagannathan, Kara W. Chew, Mark J. Giganti, Michael D. Hughes, Carlee Moser, Mark J. Main, Phillip D. Monk, Arzhang Cyrus Javan, Jonathan Z. Li, Courtney V. Fletcher, Caitlyn McCarthy, David A. Wohl, Eric S. Daar, Joseph J. Eron, Judith S. Currier, Upinder Singh, Davey M. Smith, William Fischer, Kara Chew, David (Davey) Smith, Eric Daar, David Wohl, Judith Currier, Joseph Eron, Michael Hughes, Mark Giganti, Justin Ritz, Lara Hosey, Jhoanna Roa, Nilam Patel, Kelly Colsh, Irene Rwakazina, Justine Beck, Scott Sieg, Jonathan Li, Courtney Fletcher, Teresa Evering, Rachel Bender Ignacio, Sandra Cardoso, Katya Corado, Nikolaus Jilg, Alan Perelson, Sandy Pillay, Cynthia Riviere, Babafemi Taiwo, Joan Gottesman, Matthew Newell, Susan Pedersen, Joan Dragavon, Cheryl Jennings, Brian Greenfelder, William Murtaugh, Jan Kosmyna, Morgan Gapara, Akbar Shahkolahi, Gerald Pierone, Juliana Elliott, Jeffrey Jacobson, Leila Hojat, Julie Pasternak, Jonathan Berardi, Celine Arar, Yevgeniy Bukhman, Manish Jain, Eugene Bukhman, Sadia Shaik, Timothy Hatlen, Kelly Dooley, Becky Becker, Adaliah Wilkins, Jose Pérez, Eloy Roman, Heriberto Fernández, Keila Hoover, James Renfroe, Mauney Weldon, Genei Bougher, Carlos Malvestutto, Heather Harber, Robyn Cicarella, Gene Neytman, Jack Herman, Craig Herman, Mariam Aziz, Joan Swiatek, Divya Pathak, Madhu Choudhary, Jennifer Sullivano, Olayemi Osiyemi, Myriam Izquierdo, Odelsey Torna, Aleen Khodabakhshian, Samantha Fortier, Constance Benson, Steven Hendrickx, Rosemarie Ramirez, Anne Luetkemeyer, Suzanne Hendler, Dennis Dentoni-Lasofsky, Mario Castro, Leslie Spikes, Chase Hall, Jonathan Oakes, Amy James Loftis, Pablo Tebas, William Short, Sarah McGuffin, Chris Jonsson, Rachel Presti, Alem Haile

Publikováno v: EClinicalMedicine, Vol 65, Iss , Pp 102250- (2023)

Summary: Background: With the emergence of SARS-CoV-2 variants resistant to monoclonal antibody therapies and limited global access to therapeutics, the evaluation of novel therapeutics to prevent progression to severe COVID-19 remains a critical nee

Externí odkaz: https://doaj.org/article/454735c4a8b341a688fdabe4d9bc0450

Switching to Dolutegravir/Lamivudine Two-Drug Regimen: Durability and Virologic Outcomes by Age, Sex, and Race in Routine US Clinical Care.

Autor: Jr, Gerald Pierone, Brunet, Laurence, Fusco, Jennifer S, Henegar, Cassidy E, Sarkar, Supriya, Van Wyk, Jean, Vannappagari, Vani, Wohlfeiler, Michael B, Fusco, Gregory P

Publikováno v: HIV/AIDS - Research & Palliative Care; Apr2024, Vol. 16, p133-140, 8p

Diet in a global cohort of adults with HIV at low-to-moderate traditional cardiovascular disease risk

Autor: Kathleen V. Fitch, Sara A. McCallum, Kristine M. Erlandson, Edgar Turner Overton, Markella V. Zanni, Carl Fichtenbaum, Judith A. Aberg, Evelynne S. Fulda, Emma M. Kileel, Laura E. Moran, Gerald S. Bloomfield, Richard M. Novak, Sigrid Pérez-Frontera, Alexandra Abrams-Downey, Gerald Pierone, Nagalingeswaran Kumarasamy, Kiat Ruxrungtham, Rosie Mngqibisa, Pamela S. Douglas, Heather J. Ribaudo, Steven K. Grinspoon

Publikováno v: AIDS. 36:1997-2003

To characterize diet quality across a global cohort of people with HIV (PWH).Cross-sectional analysis.Leveraging REPRIEVE data from baseline across five Global Burden of Disease (GBD) regions, we analyzed participant responses to the Rapid Eating Ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312572621088b6cf64071e5cbf4f0fc5
https://doi.org/10.1097/qad.0000000000003344

1284. Suppressed Switch to DTG/3TC 2-Drug Regimen Vs. BIC- or DTG-Based 3-Drug Regimens

Autor: Gerald Pierone, Jennifer S Fusco, Laurence Brunet, Vani Vannappagari, Supriya Sarkar, Cassidy Henegar, Jean A van Wyk, Andrew Zolopa, Gregory P Fusco

Publikováno v: Open Forum Infectious Diseases. 9

Background Real-world effectiveness of fixed dose dolutegravir/lamivudine (DTG/3TC) two-drug regimens (2DR) during the first 24 months of availability in the US was compared to common three-drug regimens (3DRs) among suppressed antiretroviral therapy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef0a6ba8301816878e2c419df461387c
https://doi.org/10.1093/ofid/ofac492.1115

Evolocumab in HIV-Infected Patients With Dyslipidemia

Autor: Franck Boccara, Princy N. Kumar, Bruno Caramelli, Alexandra Calmy, J. Antonio G. López, Sarah Bray, Marcoli Cyrille, Robert S. Rosenson, David Baker, Mark Bloch, Robert Finlayson, Jennifer Hoy, Kenneth Koh, Norman Roth, Stephane De Wit, Eric Florence, Linos Vandekerckhove, Jose Valdez Ramalho Madruga, Sandra Wagner Cardoso, Greg Bondy, Michael Gill, George Tsoukas, Sylvie Trottier, Marek Smieja, Christine Katlama, Fabrice Bonnet, Francois Raffi, Laurent Cotte, Jean-Michel Molina, Jacques Reynes, Antonios Papadopoulos, Simeon Metallidis, Vassilios Paparizos, Vasileios Papastamopoulos, Cristina Mussini, Massimo Galli, Andrea Antinori, Antonio Di Biagio, Pierluigi Viale, Andrzej Horban, Nuno Marques, Daniel Coutinho, Joaquim Oliveira, Paula Freitas, Liliana-Lucia Preotescu, Iosif Marincu, Rodica Silaghi, Sorin Rugina, Noluthando Mwelase, Sheena Kotze, Jose Ignacio Bernardino de la Serna, Vicente Estrada Perez, Esteban Martinez, Adrian Curran, Dominique Laurent Braun, Enos Bernasconi, Matthias Cavassini, John Walsh, Julie Fox, Graeme Moyle, Robert Rosenson, Jamie Morano, Jason Baker, Gerald Pierone, Carl Fichtenbaum, Paul Benson, Deborah Goldstein, Joseph Sacco, Princy Kumar, Robert Grossberg, Kara Chew, Christopher DeFilippi, Vilma Drelichman, Norman Markowitz, David Parenti, Katherine Doktor, Paul Thompson

Publikováno v: Journal of the American College of Cardiology. 75:2570-2584

Background People living with HIV (PLHIV) are at increased risk of atherosclerotic cardiovascular disease (ASCVD) and prone to statin-related adverse events from drug-drug interactions with certain antiretroviral regimens. Objectives This study sough

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de4c638f1c99a5aa5c7fc8cce88a955f
https://doi.org/10.1016/j.jacc.2020.03.025