Výsledky vyhledávání - "Gerald, Krystal"

Akademický článek

A ketogenic diet rich in fish oil is superior to other fats in preventing NNK-induced lung cancer in A/J mice

Autor: Ingrid Elisia, Michelle Yeung, Sara Kowalski, Taras Shyp, Jason Tee, Serena Hollman, Amy Wong, Janette King, Roger Dyer, Poul H. Sorensen, Gerald Krystal

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Abstract Given that ketogenic diets (KDs) are extremely high in dietary fat, we compared different fats in KDs to determine which was the best for cancer prevention. Specifically, we compared a Western and a 15% carbohydrate diet to seven different K

Externí odkaz: https://doaj.org/article/57ab62a0bc3e4659ba793b9879e8ec63

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Akademický článek

Feasibility and metabolic outcomes of a well-formulated ketogenic diet as an adjuvant therapeutic intervention for women with stage IV metastatic breast cancer: The Keto-CARE trial.

Autor: Alex Buga, David G Harper, Teryn N Sapper, Parker N Hyde, Brandon Fell, Ryan Dickerson, Justen T Stoner, Madison L Kackley, Christopher D Crabtree, Drew D Decker, Bradley T Robinson, Gerald Krystal, Katherine Binzel, Maryam B Lustberg, Jeff S Volek

Publikováno v: PLoS ONE, Vol 19, Iss 1, p e0296523 (2024)

PurposeKetogenic diets may positively influence cancer through pleiotropic mechanisms, but only a few small and short-term studies have addressed feasibility and efficacy in cancer patients. The primary goals of this study were to evaluate the feasib

Externí odkaz: https://doaj.org/article/e3e174b5fe394c72acd1db1fc0e7a894

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Akademický článek

Wild Chaga (Inonotus obliquus) modulates inflammation, neural cell survival and inhibits proliferation of cancer cells

Autor: Susan SC Cheung, Garyen Chong, Ingrid Elisia, David Hasman, Martin Lee, Linda Chang, Ziliang Ao, Djamel Khelifi, Gerald Krystal, Joseph Tai

Publikováno v: Pharmacological Research - Modern Chinese Medicine, Vol 9, Iss , Pp 100328- (2023)

Background and Aim: Inonotus obliquus (Ach. Ex. Pers), commonly known as Chaga, is a parasitic fungus that grows on birch trees. Indigenous North Americans and Northern Eurasians have used Chaga tea as a folk medicine for centuries, and there are cur

Externí odkaz: https://doaj.org/article/93d84a0551b14708931c1048700a805c

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Akademický článek

Development of a novel human triculture model of non-alcoholic fatty liver disease and identification of berberine as ameliorating steatosis, oxidative stress and fibrosis

Autor: Hossein Rafiei, Michelle Yeung, Sara Kowalski, Gerald Krystal, Ingrid Elisia

Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)

Objectives: Non-alcoholic fatty liver disease (NAFLD) and its progression to non-alcoholic steatohepatitis (NASH) and hepatocarcinoma is a serious and growing problem. However, the development of new therapies is severely hindered by a lack of high-t

Externí odkaz: https://doaj.org/article/dca278fd60ba4901964c68bc8ba6004c

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Akademický článek

Omega 3 supplementation reduces C-reactive protein, prostaglandin E2 and the granulocyte/lymphocyte ratio in heavy smokers: An open-label randomized crossover trial

Autor: Ingrid Elisia, Michelle Yeung, Sara Kowalski, Jennifer Wong, Hossein Rafiei, Roger A. Dyer, Sukhinder Atkar-Khattra, Stephen Lam, Gerald Krystal

Publikováno v: Frontiers in Nutrition, Vol 9 (2022)

ObjectivesGiven the current controversy concerning the efficacy of omega 3 supplements at reducing inflammation, we evaluated the safety and efficacy of omega 3 on reducing inflammation in people with a 6-year lung cancer risk >1.5% and a C reactive

Externí odkaz: https://doaj.org/article/7450143aa15648f2b6e9bc31218ecffa

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Akademický článek

A low carbohydrate diet high in fish oil and soy protein delays inflammation, hematopoietic stem cell depletion, and mortality in miR-146a knock-out mice

Autor: Ingrid Elisia, Sara Kowalski, Michelle Yeung, Jennifer Wong, Jennifer M. Grants, Aly Karsan, Gerald Krystal

Publikováno v: Frontiers in Nutrition, Vol 9 (2022)

Since our previous studies found a low carbohydrate (CHO) diet containing soy protein and fish oil (15%Amylose/Soy/FO) significantly reduced lung and breast cancer in mice we asked herein if this low CHO diet could also delay the onset of myeloid mal

Externí odkaz: https://doaj.org/article/689a3013769c40378a77ad78f78bf77e

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Akademický článek

CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development

Publikováno v: OncoImmunology, Vol 11, Iss 1 (2022)

Current immunotherapies for lung cancer are only effective in a subset of patients. Identifying tumor-derived factors that facilitate immunosuppression offers the opportunity to develop novel strategies to supplement and improve current therapeutics.

Externí odkaz: https://doaj.org/article/2c2a00203bef4e89885342925d64134f

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Akademický článek

Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors

Autor: Deborah Ayeni, Braden Miller, Alexandra Kuhlmann, Ping-Chih Ho, Camila Robles-Oteiza, Mmaserame Gaefele, Stellar Levy, Fernando J. de Miguel, Curtis Perry, Tianxia Guan, Gerald Krystal, William Lockwood, Daniel Zelterman, Robert Homer, Zongzhi Liu, Susan Kaech, Katerina Politi

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)

Abstract Background Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibitors (TKIs) like erlotinib are effective for treating patients with EGFR mutant lung cancer; however, drug resistance inevitably emerges. Approaches to combine immunoth

Externí odkaz: https://doaj.org/article/747919cbf484433eaa47ef5535f2fc44

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