Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gera L, Jellema"'
Autor:
Mirco Govoni, Michele Bassi, Stefano Vezzoli, Germano Lucci, Aida Emirova, Marie Anna Nandeuil, Stefano Petruzzelli, Gera L. Jellema, Ebenezer K. Afolabi, Brendan Colgan, Brian Leaker, Oliver Kornmann, Kai Michael Beeh, Henrik Watz, Dave Singh
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Although phosphodiesterase-4 (PDE4) inhibitors have been shown to reduce COPD exacerbation rate, their biological mechanism of action is not completely elucidated at the molecular level. We aimed to characterise the whole genome g
Externí odkaz:
https://doaj.org/article/329954abcd014a2482d1ae81f7bede63
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Assessments of airways inflammation in patients with chronic obstructive pulmonary disease (COPD) require semi-invasive procedures and specialized sample processing know-how. In this study we aimed to set up and validate a novel non-invas
Externí odkaz:
https://doaj.org/article/f3b0720ab26f477e975dfda16b3d1baa
Autor:
Heather L. Blackburn, Seóna McErlean, Gera L. Jellema, Ryan van Laar, Marina N. Vernalis, Darrell L. Ellsworth
Publikováno v:
Genomics Data, Vol 4, Iss C, Pp 50-53 (2015)
Heart disease and related sequelae are a leading cause of death and healthcare expenditure throughout the world. Although many patients opt for surgical interventions, lifestyle modification programs focusing on nutrition and exercise have shown subs
Externí odkaz:
https://doaj.org/article/27808d9fd81b4ec0aa9363b2c1bd0064
Autor:
Henrik Watz, Oliver Kornmann, Aida Emirova, Dave Singh, Deborah Balzano, Marie Anna Nandeuil, Gera L. Jellema, Michele Bassi, Brian Leaker, Ebenezer K. Afolabi, Mirco Govoni, Kai Michael Beeh, Germano Lucci
Publikováno v:
Journal of Cellular and Molecular Medicine
Chronic obstructive pulmonary disease (COPD) patients with higher eosinophil counts are associated with increased clinical response to phosphodiesterase‐4‐inhibitors (PDE4i). However, the underlying inflammatory mechanisms associated with this in
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Background: Assessments of airways inflammation in patients with chronic obstructive pulmonary disease (COPD) require semi-invasive procedures and specialized sample processing know-how. In this study we aimed to set up and validate a novel non-invas
Autor:
Mark R. Middleton, Sandra Van Schaeybroeck, P S Virdee, Diane Colinson, Anita Lavery, Steven Walker, Richard D. Kennedy, Gera L. Jellema, Julie Turbitt, Damian T. McManus, Martin Eatock, Anne L. Thomas, Z. Miedzybrodzka, Leanne Stevenson, Paul Harkin, Gemma E Logan, Richard C. Turkington, Russell D. Petty, Leena Elhussein
4539 Background: The Dual Erb B Inhibition in Oesophago-gastric Cancer (DEBIOC) trial reported an acceptable safety profile for neoadjuvant Xelox +/- AZD8931 but limited efficacy. We utilized EAC patient samples from DEBIOC to evaluate the impact of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e026ef075ce1231c6ea8cf4235d8a077
https://ora.ox.ac.uk/objects/uuid:735c3aa3-9673-4862-88ee-aaaaa0a637e4
https://ora.ox.ac.uk/objects/uuid:735c3aa3-9673-4862-88ee-aaaaa0a637e4
Autor:
Brendan Colgan, Michele Bassi, Stefano Vezzoli, Mirco Govoni, Germano Lucci, Oliver Kornmann, Ebenezer K. Afolabi, Aida Emirova, Gera L. Jellema, Kai Michael Beeh, Dave Singh, Marie Anna Nandeuil, Brian Leaker, Stefano Petruzzelli, Henrik Watz
Publikováno v:
Respiratory Research
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Background Although phosphodiesterase-4 (PDE4) inhibitors have been shown to reduce COPD exacerbation rate, their biological mechanism of action is not completely elucidated at the molecular level. We aimed to characterise the whole genome gene expre
Autor:
Marina N. Vernalis, Kimberly A. Mamula, Renata J.M. Engler, Ryan van Laar, Fionnuala A. McDyer, Darrell L. Ellsworth, Nicholas S. Costantino, Heather L. Blackburn, Gera L. Jellema
Publikováno v:
Obesity. 23:1312-1319
Objective To examine relationships between weight loss through changes in lifestyle and peripheral blood gene expression profiles. Methods A prospective nonrandomized trial was conducted over 1 year in participants undergoing intensive lifestyle modi
Autor:
Elaine W. Kay, Noel W. Clarke, Andrena McCavigan, Christopher S. Foster, Simon S. McDade, Christopher G. Eden, Gemma E Logan, D. Paul Harkin, Steven Walker, Catherine Davidson, David E. Neal, David Waugh, Bethanie Price, Christopher Steele, Jaine K. Blayney, Amir Sherif, Hardev Pandha, Richard D. Kennedy, Gera L. Jellema, Anne Y. Warren, Viktor Berge, Ian G. Mills, R. William G. Watson, Malcolm David Mason, Aud Svindland, Adam Uprichard, Laura A. Knight
Publikováno v:
Walker, S M, Knight, L A, McCavigan, A M, Logan, G E, Berge, V, Sherif, A, Pandha, H, Warren, A Y, Davidson, C, Uprichard, A, Blayney, J K, Price, B, Jellema, G L, Steele, C J, Svindland, A, McDade, S S, Eden, C G, Foster, C, Mills, I G, Neal, D E, Mason, M D, W Kay, E, Waugh, D J, Harkin, D P, Watson, R W, Clarke, N W & Kennedy, R D 2017, ' Molecular Subgroup of Primary Prostate Cancer Presenting with Metastatic Biology ', European Urology, vol. 72, no. 4, pp. 509 . https://doi.org/10.1016/j.eururo.2017.03.027
Background: Approximately 4-25% of patients with early prostate cancer develop disease recurrence following radical prostatectomy.Objective: To identify a molecular subgroup of prostate cancers with metastatic potential at presentation resulting in a
Autor:
Darrell L, Ellsworth, Kimberly A, Mamula, Heather L, Blackburn, Fionnuala A, McDyer, Gera L, Jellema, Ryan, van Laar, Nicholas S, Costantino, Renata J M, Engler, Marina N, Vernalis
Publikováno v:
Obesity (Silver Spring, Md.). 23(6)
To examine relationships between weight loss through changes in lifestyle and peripheral blood gene expression profiles.A prospective nonrandomized trial was conducted over 1 year in participants undergoing intensive lifestyle modification to reverse