Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Ger J, van der Vusse"'
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0261288 (2022)
Blood-borne fatty acids (Fa) are important substrates for energy conversion in the mammalian heart. After release from plasma albumin, Fa traverse the endothelium and the interstitial compartment to cross the sarcolemma prior to oxidation in the card
Externí odkaz:
https://doaj.org/article/35a382b56d424d54af0a84d2adb5835f
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 12, p e1004666 (2015)
Despite the importance of oxidation of blood-borne long-chain fatty acids (Fa) in the cardiomyocytes for contractile energy of the heart, the mechanisms underlying the transfer of Fa from the coronary plasma to the cardiomyocyte is still incompletely
Externí odkaz:
https://doaj.org/article/200179ef91f34fdeba4de8113593a37f
Autor:
Martijn L L Chatrou, Jack P Cleutjens, Ger J van der Vusse, Ruben B Roijers, Peter H A Mutsaers, Leon J Schurgers
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142335 (2015)
Vascular calcification is associated with poor cardiovascular outcome. Histochemical analysis of calcification and the expression of proteins involved in mineralization are usually based on whole section analysis, thereby often ignoring regional diff
Externí odkaz:
https://doaj.org/article/14a208deb6984307991065de4712e2ba
Fasting-induced changes in the expression of genes controlling substrate metabolism in the rat heart
Autor:
Karin A.J.M. Van der Lee, Peter H.M. Willemsen, Sonia Samec, Josiane Seydoux, Abdul G. Dulloo, Maurice M.A.L. Pelsers, Jan F.C. Glatz, Ger J. Van der Vusse, Marc Van Bilsen
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 11, Pp 1752-1758 (2001)
During fasting, when overall metabolism changes, the contribution of glucose and fatty acids (FA) to cardiac energy production alters as well. Here, we examined if the heart is able to adapt to such fasting-induced changes by modulation of its gene e
Externí odkaz:
https://doaj.org/article/8f516e714e194cb18f43741e41dc0280
Autor:
Karin A. J.M. van der Lee, Michaël M. Vork, Johan E. De Vries, Peter H.M. Willemsen, Jan F.C. Glatz, Robert S. Reneman, Ger J. Van der Vusse, Marc Van Bilsen
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 1, Pp 41-47 (2000)
Long-chain fatty acids are the most important substrates for the heart. In addition, they have been shown to affect signalling pathways and gene expression. To explore the effects of long-chain fatty acids on cardiac gene expression, neonatal rat ven
Externí odkaz:
https://doaj.org/article/7ed4fbca21cf4d869daf6f4abff19f02
Autor:
Frans A. Van Nieuwenhoven, Joost J.F.P. Luiken, Yvonne F. De Jong, Paul A. Grimaldi, Ger J. Van der Vusse, Jan F.C. Glatz
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 10, Pp 2039-2047 (1998)
Fatty acid translocase (FAT/CD36) is a membrane protein putatively involved in the transmembrane transport of long-chain fatty acids. We tested the hypothesis that expression of this protein in H9c2, a rat heart cell line normally not expressing FAT,
Externí odkaz:
https://doaj.org/article/f276dd6cbd6746ada6085cc28433173d
Autor:
Marc van Bilsen, Anneleen Daniels, Olaf Brouwers, Ben J A Janssen, Wouter J A Derks, Agnieszka E Brouns, Chantal Munts, Casper G Schalkwijk, Ger J van der Vusse, Frans A van Nieuwenhoven
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85078 (2014)
BACKGROUND: Type 2 diabetes is frequently associated with co-morbidities, including hypertension. Here we investigated if hypertension is a critical factor in myocardial remodeling and the development of cardiac dysfunction in type 2 diabetic db/db m
Externí odkaz:
https://doaj.org/article/0971133d3b4e4f369d73c74685f0d613
Publikováno v:
Analysis and Simulation of the Cardiac System — Ischemia ISBN: 9781003068341
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f2c5ff017d11df6328f706aa7db41d
https://doi.org/10.4324/9781003068341-31
https://doi.org/10.4324/9781003068341-31
Autor:
Ger J. van der Vusse, Frits W. Prinzen, Marc van Bilsen, Fawzi A. Babiker, Frans A. van Nieuwenhoven, Ilka Lorenzen-Schmidt, L. H. E. H. Snoeckx, Chantal Munts, Erik Blaauw
Publikováno v:
Journal of Cardiovascular Translational Research, 6(5), 861-869. Springer
Connective Tissue Growth Factor (CTGF, CCN2) is considered to play an important role in cardiac remodelling. We studied whether stretch is a primary stimulus to induce CTGF expression in vivo in rabbit heart, and in vitro in isolated cardiomyocytes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d08c2551d7068b73992e292c6cb978
https://cris.maastrichtuniversity.nl/en/publications/80fb81d9-8d79-43aa-99d7-e336ea2d7156
https://cris.maastrichtuniversity.nl/en/publications/80fb81d9-8d79-43aa-99d7-e336ea2d7156
Autor:
Hans-Paul Juretschke, Claudia Neumann-Haefelin, Frans A. van Nieuwenhoven, Marc van Bilsen, Ger J. van der Vusse, Dominik Linz, Anneleen Daniels, Chantal Munts, Thorsten Sadowski, Sven Ruf, Hartmut Rütten
Publikováno v:
European journal of heart failure, 14(2), 193-201. Wiley
Aims Type 2 diabetes mellitus (DM) leads to cardiac dysfunction irrespective of hypertension and coronary artery disease; this is called diabetic cardiomyopathy. Here, we investigated the severity of diabetic cardiomyopathy and myocardial remodelling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d39bd6dc1de3585bc0449d78d469d5
https://doi.org/10.1093/eurjhf/hfr166
https://doi.org/10.1093/eurjhf/hfr166