Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Geou Yarh Liou"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6665 (2024)
Reactive oxygen species (ROS) participate in almost all disorders, including cancer. Many factors, including aging, a high-fat diet, a stressful lifestyle, smoking, infection, genetic mutations, etc., lead to elevated levels of ROS. Prostate cancer,
Externí odkaz:
https://doaj.org/article/ffaf592b21484b04bb0c017975272e35
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4726 (2024)
Pancreatic ductal adenocarcinoma (PDAC) can originate from acinar-to-ductal metaplasia (ADM). Pancreatic acini harboring oncogenic Kras mutations are transdifferentiated to a duct-like phenotype that further progresses to become pancreatic intraepith
Externí odkaz:
https://doaj.org/article/3a1d94349e5e4a25bc7033b7e23731e0
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106820- (2023)
Summary: The innate immune system has a key role in pancreatic cancer initiation, but the specific contribution of different macrophage populations is still ill-defined. While inflammatory (M1) macrophages have been shown to drive acinar-to-ductal me
Externí odkaz:
https://doaj.org/article/ee1aeaca9d56411a9f284027194122df
Autor:
Alicia K. Fleming Martinez, Heike R. Döppler, Ligia I. Bastea, Brandy H. Edenfield, Geou-Yarh Liou, Peter Storz
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104327- (2022)
Summary: Desmoplasia around pancreatic lesions is a barrier for immune cells and a hallmark of developing and established pancreatic cancer. However, the contribution of the innate immune system to this process is ill-defined. Using the KC mouse mode
Externí odkaz:
https://doaj.org/article/91998440ba57446fb25042eefda52ac9
Autor:
Justin K. Messex, Geou-Yarh Liou
Publikováno v:
Life, Vol 13, Iss 2, p 333 (2023)
Prostate cancer is the most prevalent type of cancer in senior American men. Currently, the five-year survival rate after the initial diagnosis of prostate cancer is close to 100%. However, it is also the second leading cause of cancer death in senio
Externí odkaz:
https://doaj.org/article/c2f3110b6bdc48c992a24d9822ee3014
Autor:
Alicia K. Fleming Martinez, Heike R. Döppler, Ligia I. Bastea, Brandy Edenfield, Tushar Patel, Michael Leitges, Geou-Yarh Liou, Peter Storz
Publikováno v:
iScience, Vol 24, Iss 1, Pp 102019- (2021)
Summary: Doublecortin-like kinase 1 (DCLK1)-positive pancreatic cancer stem cells develop at a precancerous stage and may contribute to the lack of efficacy of pancreatic cancer therapy. Although PanIN cells express oncogenic KRas and have an increas
Externí odkaz:
https://doaj.org/article/97c1c4b06bc6435e98af436af67fd633
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4247 (2022)
Prostate cancer development and progression are associated with increased infiltrating macrophages. Prostate cancer is derived from prostatic intraepithelial neoplasia (PIN) lesions. However, the effects macrophages have on PIN progression remain unc
Externí odkaz:
https://doaj.org/article/cfebfd8d933843ddb40e06cc0cf66dee
Publikováno v:
Antioxidants, Vol 11, Iss 1, p 137 (2022)
Pancreatic acinar-to-ductal metaplasia (ADM) is a reversible process that occurs after pancreatic injury, but becomes permanent and leads to pancreatic lesions in the presence of an oncogenic mutation in KRAS,. While inflammatory macrophage-secreted
Externí odkaz:
https://doaj.org/article/c414ddc89f2d4b27afe03dcdaf090ff2
Autor:
Geou-Yarh Liou, Ligia Bastea, Alicia Fleming, Heike Döppler, Brandy H. Edenfield, David W. Dawson, Lizhi Zhang, Nabeel Bardeesy, Peter Storz
Publikováno v:
Cell Reports, Vol 19, Iss 7, Pp 1322-1333 (2017)
The contributions of the innate immune system to the development of pancreatic cancer are still ill defined. Inflammatory macrophages can initiate metaplasia of pancreatic acinar cells to a duct-like phenotype (acinar-to-ductal metaplasia [ADM]), whi
Externí odkaz:
https://doaj.org/article/3ff5843d69ad48958952a7a78e9fe61c
Autor:
Peter Storz, David W. Dawson, Lizhi Zhang, Brandy Edenfield, Brian Necela, Heike Döppler, Geou-Yarh Liou
Supplementary Figure S3 shows analysis for microvascularization (A), alcian blue staining of tissue sections (B), and ICAM-1 expression in human samples (C).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a73fb173f17e77a8bc3f2449e01f3c
https://doi.org/10.1158/2159-8290.22530177.v1
https://doi.org/10.1158/2159-8290.22530177.v1
