Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Georgy Th Guria"'
Autor:
Tatiana Yu Salikhova, Denis M Pushin, Igor V Nesterenko, Lyudmila S Biryukova, Georgy Th Guria
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0272342 (2022)
Shear-induced platelet activation (SIPAct) is an important mechanism of thrombosis initiation under high blood flow. This mechanism relies on the interaction of platelets with the von Willebrand factor (VWF) capable of unfolding under high shear stre
Externí odkaz:
https://doaj.org/article/1371a9ad7d6147ecaa302c29514ff73d
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234501 (2020)
Shear-induced conformational changes of von Willebrand factor (VWF) play an important role in platelet activation. A novel approach describing VWF unfolding on the platelet surface under dynamic shear stress is proposed. Cumulative effect of dynamic
Externí odkaz:
https://doaj.org/article/7e1b99d3f21445ffbf4c1b44ad7e6388
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0211646 (2019)
In the present study, we investigated the capabilities of a novel ultrasonic approach for real-time control of fibrinolysis under flow conditions. Ultrasonic monitoring was performed in a specially designed experimental in vitro system. Fibrinolytic
Externí odkaz:
https://doaj.org/article/44bbaae3ec304743b1db4a7171117e04
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134028 (2015)
Increased shear stress such as observed at local stenosis may cause drastic changes in the permeability of the vessel wall to procoagulants and thus initiate intravascular blood coagulation. In this paper we suggest a mathematical model to investigat
Externí odkaz:
https://doaj.org/article/d32e15d8d29a47c38e435116a09deb2f
Autor:
Tatiana Yu Salikhova, Denis M. Pushin, Igor V. Nesterenko, Lyudmila S. Biryukova, Georgy Th Guria
Publikováno v:
PloS one. 17(10)
Shear-induced platelet activation (SIPAct) is an important mechanism of thrombosis initiation under high blood flow. This mechanism relies on the interaction of platelets with the von Willebrand factor (VWF) capable of unfolding under high shear stre
Autor:
Georgy Th. Guria, Ivan V. Prikhodko
Publikováno v:
Entropy, Vol 23, Iss 1245, p 1245 (2021)
Entropy
Volume 23
Issue 10
Entropy
Volume 23
Issue 10
Nucleation theory has been widely applied for the interpretation of critical phenomena in nonequilibrium systems. Ligand-induced receptor clustering is a critical step of cellular activation. Receptor clusters on the cell surface are treated from the
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234501 (2020)
PLoS ONE
PLoS ONE
Shear-induced conformational changes of von Willebrand factor (VWF) play an important role in platelet activation. A novel approach describing VWF unfolding on the platelet surface under dynamic shear stress is proposed. Cumulative effect of dynamic
Autor:
Shakhla N. Shirinli, Svetlana G. Uzlova, Konstantin G. Guria, Dmitry A. Ivlev, Georgy Th. Guria
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0211646 (2019)
PLoS ONE
PLoS ONE
In the present study, we investigated the capabilities of a novel ultrasonic approach for real-time control of fibrinolysis under flow conditions. Ultrasonic monitoring was performed in a specially designed experimental in vitro system. Fibrinolytic
Publikováno v:
Medical hypotheses. 104
The efficiency of anti-tumour drug strongly depends on its dose. Higher drug doses and exposure times usually result in better treatment. It is why the implementation of high-dose treatment is always attractive. However, most of the drug delivery tec