Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Georgy Sagaradze"'
Autor:
Georgy Sagaradze, Anna Monakova, Nataliya Basalova, Vladimir Popov, Vadim Balabanyan, Anastasia Efimenko
Publikováno v:
Biomedical Journal, Vol 45, Iss 4, Pp 607-614 (2022)
Stem and progenitor cells located within stem cell niches maintain the renewal and regeneration of tissues and organs throughout the life of an adult organism. Stem cell niche component dysfunction might alter the activity of stem cells and ultimatel
Externí odkaz:
https://doaj.org/article/b8bc2b45887a429ab01ef8e86a71085b
Autor:
Cora N. Sternberg, Nara Shin, Konstantin Chernyshov, Fabio Calabro, Linda Cerbone, Giuseppe Procopio, Natalia Miheecheva, Georgy Sagaradze, Alisa Zaichikova, Naira Samarina, Alexandra Boyko, Jessica H. Brown, Leysan Yunusova, Daniela Guevara, Jyothi Manohar, Michael Sigouros, Majd Al Assaad, Olivier Elemento, Juan Miguel Mosquera
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Although immune checkpoint inhibitors (ICIs) are increasingly used as second-line treatments for urothelial cancer (UC), only a small proportion of patients respond. Therefore, understanding the mechanisms of response to ICIs is critical to improve c
Externí odkaz:
https://doaj.org/article/261fadd6de394c4e909ca5e76ae4df64
Autor:
Georgy Sagaradze, Nataliya Basalova, Vladimir Kirpatovsky, Dmitry Ohobotov, Peter Nimiritsky, Olga Grigorieva, Vladimir Popov, Armais Kamalov, Vsevolod Tkachuk, Anastasia Efimenko
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-10 (2019)
Abstract Background Injury of stem cell niches may disturb tissue homeostasis and regeneration coordinated by specific niche components. Yet, the mechanisms of stem cell niche restoration remain poorly understood. Herein, we examined the role of mese
Externí odkaz:
https://doaj.org/article/2c7d56ec7e8640b2af7ec36394f32401
Autor:
Maxim Karagyaur, Stalik Dzhauari, Nataliya Basalova, Natalia Aleksandrushkina, Georgy Sagaradze, Natalia Danilova, Pavel Malkov, Vladimir Popov, Mariya Skryabina, Anastasia Efimenko, Vsevolod Tkachuk
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2031 (2021)
Multipotent mesenchymal stromal cells (MSCs) are considered to be critical contributors to injured tissue repair and regeneration, and MSC-based therapeutic approaches have been applied to many peripheral and central neurologic disorders. It has been
Externí odkaz:
https://doaj.org/article/f5348e193cf84785945310e2af621eb0
Autor:
Nataliya Basalova, Georgy Sagaradze, Mikhail Arbatskiy, Evgeniy Evtushenko, Konstantin Kulebyakin, Olga Grigorieva, Zhanna Akopyan, Natalia Kalinina, Anastasia Efimenko
Publikováno v:
Cells, Vol 9, Iss 5, p 1272 (2020)
Fibroblasts differentiation into myofibroblasts is a central event of tissue fibrosis. Multipotent mesenchymal stromal cells (MSCs) secretome can interfere with fibrosis development; despite precise underlying mechanisms remain unclear. In this study
Externí odkaz:
https://doaj.org/article/e6508d7f70ea473f93a76cb18c335127
Akademický článek
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Autor:
Anna Monakova, Georgy Sagaradze, Nataliya Basalova, Vladimir Popov, Vadim Balabanyan, Anastasia Efimenko
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 9414
Idiopathic male infertility is a highly prevalent diagnosis in developed countries with no specific treatment options. Although empirical medical treatment is widely used to restore male fertility, its efficacy remains limited and inconclusively prov
Publikováno v:
International Journal of Molecular Sciences. 24:9379
Adult stem cells maintaining tissue homeostasis and regeneration are tightly regulated by their specific microenvironments or stem cell niches. The dysfunction of niche components may alter the activity of stem cells and ultimately lead to intractabl
Autor:
Georgy Sagaradze, Anna Monakova, Nataliya Basalova, Vladimir Popov, Vadim Balabanyan, Anastasia Efimenko
Publikováno v:
Biomedical journal. 45(4)
Stem and progenitor cells located within stem cell niches maintain the renewal and regeneration of tissues and organs throughout the life of an adult organism. Stem cell niche component dysfunction might alter the activity of stem cells and ultimatel
Autor:
Olga Grigorieva, Peter Nimiritsky, V.I. Kirpatovsky, A.Y. Efimenko, A A Kamalov, Nataliya Basalova, Vladimir Popov, Georgy Sagaradze, D.A. Ohobotov
Publikováno v:
BIOTECHNOLOGY: STATE OF THE ART AND PERSPECTIVES. :235-237
The study revealed the regenerative effects of MSC and MSC secretome in a model of abdominal cryptorchidism in rats.