Výsledky vyhledávání - "Georgy Gulbekyan"

Akademický článek

Development of a Drug-Response Modeling Framework to Identify Cell Line Derived Translational Biomarkers That Can Predict Treatment Outcome to Erlotinib or Sorafenib.

Autor: Bin Li, Hyunjin Shin, Georgy Gulbekyan, Olga Pustovalova, Yuri Nikolsky, Andrew Hope, Marina Bessarabova, Matthew Schu, Elona Kolpakova-Hart, David Merberg, Andrew Dorner, William L Trepicchio

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0130700 (2015)

Development of drug responsive biomarkers from pre-clinical data is a critical step in drug discovery, as it enables patient stratification in clinical trial design. Such translational biomarkers can be validated in early clinical trial phases and ut

Externí odkaz: https://doaj.org/article/ff7240e562214215af66645a587a6a86

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Development of a Drug-Response Modeling Framework to Identify Cell Line Derived Translational Biomarkers That Can Predict Treatment Outcome to Erlotinib or Sorafenib

Autor: Hyunjin Shin, Bin Li, Olga Pustovalova, David Merberg, Andrew Hope, Marina Bessarabova, Elona Kolpakova-Hart, Andrew Dorner, Georgy Gulbekyan, Matthew Schu, Yuri Nikolsky, William L. Trepicchio

Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 6, p e0130700 (2015)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e807e7e641f06a1b670ad1f5417d853a
https://pubmed.ncbi.nlm.nih.gov/26107615

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Abstract A37: Translational biomarkers for cancer drug response: Cell line panel derived drug response signature predicts patients’ survival in a lung cancer clinic trial

Autor: Andrew Hope, Olga Pustovalova, Bin Li, Matthew Schu, Marina Bessarabova, Hyunjin Shin, Yuri Nikolsky, Georgy Gulbekyan, William L. Trepicchio

Publikováno v: Molecular Cancer Therapeutics. 12:A37-A37

Discovery of candidate drug sensitivity predictive genomic models using pre-clinical data would significantly advance the ability to timely validate such models in clinical trials and utilize them for selecting appropriate treatments for patients. He

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45b3ed01915dbc743a52ee4e3211601a
https://doi.org/10.1158/1535-7163.targ-13-a37

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