Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Georgy Galegov"'
Autor:
Id, Konstantinova, Iv, Fateev, Georgy Galegov, Pg, Deriabin, Ag, Botikov, Is, Muzyka, Vov Dk, L., Ai, Miroshnikov
Publikováno v:
Europe PubMed Central
Improved biotechnological method of receiving the antiviral drug ribavirin by the reaction of transglycosilation by addition of catalytic amounts of sodium arsenate in the reaction mixture. Such approach allows to hydrolyze the amount of the excess n
Autor:
Dg, Mal Dov, Ap, Bel Kov, Av, Il Ichev, Ei, Astashkin, Ss, Grigorian, Vl, Andronova, Georgy Galegov
Publikováno v:
Europe PubMed Central
Substances with gender action on immunity were detected in water soluble hydrolised matter from reptile carcases. The gender action was shown on isolated blood neutrophils, whole blood and in vivo by the antiviral activity on experimental animals, co
Publikováno v:
Europe PubMed Central
Two dimeric netropsin derivatives (Lys-bis-Nt 15Lys-bis-Nt) were comprehensively tested for antiviral and toxic activity in cell cultures and laboratory animals. The two compounds were found to provide effective and selective inhibition of reproducti
Publikováno v:
Europe PubMed Central
In vitro activity of interferon-alpha-2b in combination with various antioxidants against the influenza virus and Herpes simplex was studied. The standard strains and a clinical strain of Herpes simplex isolated from a patient with resistance to acyc
Autor:
Es, Matiugina, Kl, Seley-Radtke, Vl, Andronova, Georgy Galegov, Sn, Kochetkov, Al, Khandazhinskaia
Publikováno v:
Europe PubMed Central
New N¹-benzyl esters of N¹-oxide analogues of 5'-noraristeromycin were synthesized and tested as potential inhibitors of S-adenosyl-L-homocysteine hydrolase in Vaccinia virus infected cell systems.
Publikováno v:
Europe PubMed Central
The ability of acycloguanosine H-phosphate to inhibit the reproduction of herpes simplex virus type 1 (HSV-1) variants, including its acycloguanosine (acyclovir)-resistant ones, was studied. Acycloguanosine H-phosphate-resistant HSV-1 variants were o
Autor:
Vl, Andronova, Sl, Grokhovskiĭ, An, Surovaia, Gv, Gurskiĭ, Pg, Deriabin, Vov Dk, L., Georgy Galegov
Publikováno v:
Europe PubMed Central
Using the model of an experimental cutaneous infection of guinea pig males caused by herpes simple virus type 1, it is shown that application of dimerico derivatives of netropsin Lys-bis Nt and 15Lys-bis Nt in the form of polietilenglicol-based ointm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1afac7f164baad06d440930713de7aca
http://europepmc.org/abstract/med/23785759
http://europepmc.org/abstract/med/23785759
Autor:
An, Surovaia, Sl, Gorohovskiĭ, Gurskiĭ IaG, Vl, Andronova, Vs, Arkhipova, Np, Bazhulina, Georgy Galegov, Gv, Gurskiĭ
Publikováno v:
Europe PubMed Central
The protein binding to the origin of replication of the herpes simplex virus type 1 (HSV-1) is DNA helicase encoded by the UL9 gene of the herpes virus. The protein specifically binds to two binding sites in the viral DNA replication origins OriS or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2165973486296dca4330225006451a38
http://europepmc.org/abstract/med/20429277
http://europepmc.org/abstract/med/20429277
Autor:
Vl, Andronova, Sl, Grokhovskiĭ, Pg, Deriabin, Gv, Gurskiĭ, An, Surovaia, Mv, Jas Ko, Mk, Kukhanova, Sn, Kochetkov, Skoblov IuS, Georgy Galegov
Publikováno v:
Europe PubMed Central
Antiherpetic activity of the double and triple combinations, including original connections 15Lys-bis-Nt and phosphate of acycloguanosine (P-ACG), was studied in vitro. For the first time, it was demonstrated that in case of their combined use with k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cfc68ccad7b64712da66af819b6167f1
http://europepmc.org/abstract/med/25549466
http://europepmc.org/abstract/med/25549466
Publikováno v:
Europe PubMed Central
In the brain and lungs of the experimental animals contaminated by Herpes simplex-1 there were detected much higher levels of the thiobarbituric acid-stained lipid oxidation products and proteolytic activity, evident of the inflammation process. Stim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e6b92c8e8bc8dec013fe01166b978899
http://europepmc.org/abstract/med/25051710
http://europepmc.org/abstract/med/25051710