Zobrazeno 1 - 10
of 295
pro vyhledávání: '"Georgy A. Nevinsky"'
Autor:
Tatiana S. Novikova, Evgeny A. Ermakov, Elena V. Kostina, Alexander N. Sinyakov, Alexey E. Sizikov, Georgy A. Nevinsky, Valentina N. Buneva
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 12, Pp 9887-9903 (2023)
Anti-DNA antibodies are known to be classical serological hallmarks of systemic lupus erythematosus (SLE). In addition to high-affinity antibodies, the autoantibody pool also contains natural catalytic anti-DNA antibodies that recognize and hydrolyze
Externí odkaz:
https://doaj.org/article/83c7de25dc9e4570aaf20eede051c3ac
Autor:
Evgeny A. Ermakov, Mark M. Melamud, Anastasiia S. Boiko, Svetlana A. Ivanova, Alexey E. Sizikov, Georgy A. Nevinsky, Valentina N. Buneva
Publikováno v:
Life, Vol 14, Iss 10, p 1305 (2024)
Patients with systemic lupus erythematosus (SLE) are known to frequently suffer from comorbid cardiovascular diseases (CVDs). There are abundant data on cytokine levels and their role in the pathogenesis of SLE, while growth factors have received muc
Externí odkaz:
https://doaj.org/article/4260311cb7cf468aaf92175bff5922a0
Publikováno v:
Non-Coding RNA, Vol 10, Iss 5, p 48 (2024)
Following the acute phase of SARS-CoV-2 infection, certain individuals experience persistent symptoms referred to as long COVID. This study analyzed the patients categorized into three distinct groups: (1) individuals presenting rheumatological sympt
Externí odkaz:
https://doaj.org/article/df958c21965c4a46b887a7c401e9b23e
Autor:
Anna S. Tolmacheva, Sergey E. Sedykh, Margarita K. Onvumere, Anna M. Timofeeva, Lada V. Maksimenko, Natalya M. Gashnikova, Georgy A. Nevinsky
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 5, p 191 (2024)
Background: Human immunodeficiency virus (HIV) infection is associated with pronounced oxidative stress, leading to the development of various virus-associated pathologies. A wealth of evidence suggests that, along with canonical enzymes of reactive
Externí odkaz:
https://doaj.org/article/9983a84875634307adaade0f0382594a
Autor:
Anna M. Timofeeva, Liliya Sh. Shayakhmetova, Artem O. Nikitin, Tatyana A. Sedykh, Andrey L. Matveev, Daniil V. Shanshin, Ekaterina A. Volosnikova, Iuliia A. Merkuleva, Dmitriy N. Shcherbakov, Nina V. Tikunova, Sergey E. Sedykh, Georgy A. Nevinsky
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1007 (2024)
Antibodies are protein molecules whose primary function is to recognize antigens. However, recent studies have demonstrated their ability to hydrolyze specific substrates, such as proteins, oligopeptides, and nucleic acids. In 2023, two separate team
Externí odkaz:
https://doaj.org/article/8682e6b341a844b697054171485516e4
Autor:
Anna M. Timofeeva, Sergey E. Sedykh, Ekaterina A. Litvinova, Sergey A. Dolgushin, Andrey L. Matveev, Nina V. Tikunova, Georgy A. Nevinsky
Publikováno v:
Vaccines, Vol 12, Iss 4, p 426 (2024)
The rapid development of vaccines is a crucial objective in modern biotechnology and molecular pharmacology. In this context, conducting research to expedite the selection of a potent immunogen is imperative. The candidate vaccine should induce the p
Externí odkaz:
https://doaj.org/article/5f137287345444aeb46b8086c6c2bcab
Publikováno v:
Molecules, Vol 29, Iss 6, p 1382 (2024)
The exact mechanisms of MS (multiple sclerosis) evolution are still unknown. However, the development of EAE (experimental autoimmune encephalomyelitis simulating human MS) in C57BL/6 mice occurs due to the violation of bone marrow hematopoietic stem
Externí odkaz:
https://doaj.org/article/26be209295b647f1a26fd7991326bb29
Publikováno v:
Vaccines, Vol 11, Iss 9, p 1494 (2023)
The S-protein is the major antigen of the SARS-CoV-2 virus, against which protective antibodies are generated. The S-protein gene was used in adenoviral vectors and mRNA vaccines against COVID-19. While the primary function of antibodies is to bind t
Externí odkaz:
https://doaj.org/article/249e930bac8c4abdbeeefb3c4b7f8814
Autor:
Ivan Yu. Kompaneets, Sergey E. Sedykh, Valentina N. Buneva, Pavel S. Dmitrenok, Georgy A. Nevinsky
Publikováno v:
Journal of Dairy Science, Vol 105, Iss 2, Pp 950-964 (2022)
ABSTRACT: Mother's milk provides newborns with various nutrients (e.g., enzymes, proteins, peptides, hormones, antibodies) that help babies grow and protect them from bacterial and viral infections. The functions of many components of breast milk can
Externí odkaz:
https://doaj.org/article/6968a65c018b485887de26221552116b
Autor:
Evgeny A. Ermakov, Mark M. Melamud, Anastasiia S. Boiko, Daria A. Kamaeva, Svetlana A. Ivanova, Georgy A. Nevinsky, Valentina N. Buneva
Publikováno v:
Brain Sciences, Vol 13, Iss 5, p 836 (2023)
Multiple lines of evidence are known to confirm the pro-inflammatory state of some patients with schizophrenia and the involvement of inflammatory mechanisms in the pathogenesis of psychosis. The concentration of peripheral biomarkers is associated w
Externí odkaz:
https://doaj.org/article/435e6a4979444b5f9969477935e42cf7