Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Georgiy M. Manikhas"'
Autor:
Khristina B Kotiv, Alexey M. Belyaev, Georgiy M Manikhas, Anna Sidoruk, Evgeny N. Imyanitov, Anna P. Sokolenko, Galina I Mikhailiuk, Alla S Lisyanskaya, Laslo D Roman, Ekatherina A Nekrasova, Nikolay Mikaya, Tatyana Gorodnova, Alexandr O. Ivantsov, Nikolay Bondarev, Olga N Mikheyeva, K. D. Guseynov, Igor Berlev, Nataliya S Matveyeva
Publikováno v:
International Journal of Gynecologic Cancer. 28:1498-1506
ObjectivesCisplatin and mitomycin C exert high activity towards BRCA1-deficient cells. This study aimed to evaluate the efficacy of a combination of these drugs in hereditary BRCA1-associated ovarian cancer (OC).MethodsTwelve OC patients, who could n
Autor:
Ruslan Glushakov, Georgiy M Manikhas, Alla S Lisyanskaya, Ekaterina P Fadeeva, Natalia I Tapilskaya
Publikováno v:
Reviews on Clinical Pharmacology and Drug Therapy. 14:47-57
This review provides the current evidence of clinical studies on the effectiveness of endocrine therapy for breast cancer and endometrial cancer, including endometrial stromal sarcoma, by aromatase inhibitor (AI) III generation. The review presents d
Autor:
Tatyana V, Gorodnova, Khristina B, Kotiv, Alexandr O, Ivantsov, Olga N, Mikheyeva, Galina I, Mikhailiuk, Alla S, Lisyanskaya, Nikolay A, Mikaya, Konstantin D, Guseynov, Nikolay E, Bondarev, Nataliya S, Matveyeva, Ekatherina A, Nekrasova, Anna A, Sidoruk, Laslo D, Roman, Georgiy M, Manikhas, Alexey M, Belyaev, Anna P, Sokolenko, Igor V, Berlev, Evgeny N, Imyanitov
Publikováno v:
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. 28(8)
Cisplatin and mitomycin C exert high activity towards BRCA1-deficient cells. This study aimed to evaluate the efficacy of a combination of these drugs in hereditary BRCA1-associated ovarian cancer (OC).Twelve OC patients, who could not be treated by
Autor:
P. Bhar, D. Krasnojon, Georgiy M. Manikhas, John R. McGuire, William J. Gradishar, A. Makhson, Jose Iglesias, S. Cheporov, Alicia Clawson
Publikováno v:
Clinical Breast Cancer. 12:313-321
Background A randomized phase II study in first-line MBC demonstrated superior efficacy and safety of weekly nab -paclitaxel compared with docetaxel. Final survival analyses and updated safety results are reported. Patients and Methods Three hundred
Autor:
Carlos Villena, Peter Altevogt, Axel Benner, Sascha Keller, Sarah Hug, Georgiy M. Manikhas, Niko P. Bretz, Glen Kristiansen, Miguel Ángel Seguí, Christof Sohn, Amparo Ruiz, Anne Walter, Peter Lichter, K. Friedrichs, Wiebke Werft, Frederik Marmé, Andreas Schneeweiss, Anne Kathleen Rupp, Armando Santoro, Mikhail Y. Biakhov, Christian Rupp, Pedro Sánchez-Rovira, Alberto Bottini, Gerhard Moldenhauer, Peter Sinn, Xiaoli Wang, V. A. Khailenko, Barbara Burwinkel
Publikováno v:
Breast Cancer Research and Treatment. 132:819-831
Overexpression of CD24 is an independent prognostic factor for breast cancer. Recently, two polymorphisms in the CD24 gene were linked to disease risk and progression in autoimmune diseases. Here, we evaluated the clinical relevance of these polymorp
Autor:
Georgiy M. Manikhas, A. Makhson, Daniil L. Stroyakovsky, Petr K. Yablonsky, P. Bhar, Sergei V. Orlov, S. Cheporov, Jose Iglesias, Mark A. Socinski
Publikováno v:
Journal of Thoracic Oncology. 5:852-861
Introduction This nonrandomized study aimed to identify the optimal dose of every-3-week (q3w) and weekly nab -paclitaxel plus q3w carboplatin as first-line therapy in patients with advanced non-small cell lung cancer (NSCLC) for a phase 3 trial. Met
Autor:
P. Bhar, Georgiy M. Manikhas, William J. Gradishar, Alicia Clawson, D. Krasnojon, S. Cheporov, A. Makhson
Publikováno v:
Journal of Clinical Oncology. 27:3611-3619
Purpose In patients with metastatic breast cancer (MBC), nab-paclitaxel produced significantly higher antitumor activity compared with patients who received solvent-based paclitaxel. This phase II study examined the antitumor activity and safety of w
Autor:
P. Bhar, A. Clawson, Georgiy M. Manikhas, S. Cheporov, William J. Gradishar, D. Krasnojon, A. Makhson
Publikováno v:
European Journal of Cancer Supplements. 6:172
Autor:
M. J. Hawkins, D. Krasnojon, Georgiy M. Manikhas, A. Makhson, S. Cheporov, Alicia Clawson, William J. Gradishar
Publikováno v:
Journal of Clinical Oncology. 25:1032-1032
1032 Background: 130-nM albumin-bound (nab™) paclitaxel combines paclitaxel with albumin without solvents or altering either component. A cross analysis of 2 clinical trials comparing solvent-based (SB) paclitaxel 175 mg/m2 q3w to nab- paclitaxel (