Zobrazeno 1 - 5 of 5 pro vyhledávání: '"Georgios Sabatakos"'
1
Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-γ binding agents with potential application to the treatment of osteoporosis
Autor: Thomas P. Demuth, Maria E. Petrey, Maria Kontoyianni, Laufersweiler Michael Christopher, Matthew Pokross, Yili Wang, R.L. Walter, Jeffrey Tupper Roesgen, Eloise C. Richardson, Artem G. Evdokimov, Marlene Mekel, Georgios Sabatakos, Corey R. Hopkins, Steven V. O’Neil
Publikováno v: Bioorganic & Medicinal Chemistry Letters. 16:5659-5663
The synthesis and structure-activity relationships of a novel series of N-sulfonyl-2-indole carboxamides that bind to peroxisome proliferator-activated receptor gamma (PPAR-gamma) are reported. Chemical optimization of the series led to the identific
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82cd66af80d91ca5001290cff236c5d
https://doi.org/10.1016/j.bmcl.2006.08.003
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2
The Ovine CCAAT-Enhancer Binding Protein δ Gene: Cloning, Characterization, and Species-Specific Autoregulation
Autor: Gareth E. Davies, Georgios Sabatakos, Dipak Purshottam Ramji, Anthony Cryer
Publikováno v: Biochemical and Biophysical Research Communications. 271:346-352
Transcription factors belonging to the CCAAT-enhancer binding protein (C/EBP) family have been implicated in the regulation of gene expression during growth, differentiation, apoptosis, and inflammation. Autoregulation is relatively common in the mod
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ee656a09e5724893999b6a5d870a0c
https://doi.org/10.1006/bbrc.2000.2630
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3
Expression of the genes encoding CCAAT-enhancer binding protein isoforms in the mouse mammary gland during lactation and involution
Autor: Gareth E. Davies, Maria Grosse, Anthony Cryer, Dipak Purshottam Ramji, Georgios Sabatakos
Publikováno v: Biochemical Journal. 334:205-210
Transcription factors belonging to the CCAAT-enhancer binding protein (C/EBP) family have been implicated in the activation of gene expression in the mammary gland during lactation. We have therefore investigated the detailed expression profile of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308ebd77108a136cf3d0f4ea9902d07d
https://doi.org/10.1042/bj3340205
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