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Autor:
Georgios Misiakos, Ildiko Van Rhijn, David C. Young, D. Branch Moody, Mira Holzheimer, Adriaan J. Minnaard, Alexandrea K. Ramnarine, Eri Ishikawa, Tan-Yun Cheng, Sho Yamasaki, Josephine F. Reijneveld
Publikováno v:
ACS chemical biology, 15(7), 1835-1841. AMER CHEMICAL SOC
ACS Chemical Biology
ACS Chemical Biology
The first asymmetric total synthesis of three structures proposed for mycobacterial diacyl trehaloses, DAT1, DAT2, and DAT3 is reported. The presence of two of these glycolipids, DAT1 and DAT3, within different strains of pathogenic M. tuberculosis w