Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Georgios L Voulgaris"'
Autor:
Matthew E. Falagas, Margarita Kyriakidou, Georgios L. Voulgaris, Filippos Vokos, Sevasti Politi, Konstantinos S. Kechagias
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 24, Iss , Pp 342-359 (2021)
Objectives: The epidemic dimensions of the emergence of multidrug-resistant (MDR) Gram-negative bacterial infections have led to the revival of old antibiotics, including the polymyxins. Methods: We performed a review and meta-analysis to evaluate th
Externí odkaz:
https://doaj.org/article/52741b8b0b704b0f9f149f9d32e5140f
Autor:
Matthew E. Falagas, Margarita Kyriakidou, Anastasios Kapaskelis, Katerina G Tsegka, Georgios L Voulgaris
Publikováno v:
Expert Review of Anti-infective Therapy. 20:33-43
Fosfomycin is a wide spectrum bactericidal antibiotic with a unique mode of action, low toxicity, and good penetration in tissues with deep-seated infections, including bone and joint infections.Data were extracted from 19 published articles. Three h
Autor:
Margarita Kyriakidou, Matthew E. Falagas, Anthony R.M. Coates, Georgios L Voulgaris, Panagiota Giakkoupi, Yanmin Hu, Alkiviadis Vatopoulos, Kyriaki Tryfinopoulou
Publikováno v:
International Journal of Antimicrobial Agents. 53:855-858
BACKGROUND: New antibiotics are urgently needed for the treatment of multidrug resistant infections. However, the production of novel antibiotics is diminishing. The enhancement of activity of available antibiotics through synergistic combination dru
Publikováno v:
Expert review of anti-infective therapy. 18(7)
Central nervous system (CNS) infections have considerable morbidity and mortality. Fosfomycin is a broad spectrum bactericidal antibiotic with favorable pharmacokinetic properties and low toxicity, satisfactory penetration in the cerebrospinal fluid
Autor:
Konstantinos S. Kechagias, Matthew E. Falagas, Margarita Kyriakidou, Georgios L Voulgaris, Filippos Vokos, Sevasti Politi
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 24, Iss, Pp 342-359 (2021)
Introduction The epidemic dimensions of emergence of multi-drug resistant Gram-negative bacterial infections have led to the revival of old antibiotics, including polymyxins. Methods We performed a review and meta-analysis to evaluate the current lit
Publikováno v:
Expert review of anti-infective therapy. 17(6)
Introduction: The constantly increasing spread of severe infections due to multidrug-resistant (MDR) Gram-negative bacteria (GNB) is a critical threat to the global medical community. After a long period of antibiotic pipeline pause, new antibiotic c
Autor:
Nikolaos A. Triarides, Matthew E. Falagas, Florentia Athanasaki, Georgios L Voulgaris, Konstantinos Z. Vardakas
Publikováno v:
International journal of antimicrobial agents. 53(1)
Fosfomycin has been used for the treatment of infections due to susceptible and multidrug-resistant (MDR) bacteria. It inhibits bacterial cell wall synthesis through a unique mechanism of action at a step prior to that inhibited by β-lactams. Fosfom
Autor:
Konstantinos Z. Vardakas, Georgios Papanikolaou, Nicholas J. Legakis, Tilemachos Skalidis, Georgios L Voulgaris, Matthew E. Falagas
Publikováno v:
International journal of antimicrobial agents. 52(2)
TP-6076 is a synthetic fluorocycline antibiotic that inhibits bacterial protein synthesis. In this study, carbapenem-resistant Acinetobacter baumannii clinical isolates from 13 Greek hospitals were tested for susceptibility to TP-6076 and comparator
Autor:
Konstantinos Z. Vardakas, Matthew E. Falagas, Athanasios Maliaros, Georgios L Voulgaris, George Samonis
Publikováno v:
The Lancet. Infectious diseases. 18(1)
Summary Background The findings of randomised controlled trials (RCT), observational studies, and meta-analyses vary regarding the effectiveness of prolonged β-lactam infusion. We aimed to identify the effectiveness of prolonged versus short-term in
Publikováno v:
International journal of antimicrobial agents. 51(1)
Background Inhaled colistin is becoming increasingly popular against respiratory tract infections caused by multidrug resistant (MDR) Gram-negative bacteria because it may overcome the problems associated with intravenous (IV) administration. Objecti