Fabrication and Preliminary In Vitro Evaluation of 3D-Printed Alginate Films with Cannabidiol (CBD) and Cannabigerol (CBG) Nanoparticles for Potential Wound-Healing Applications

Autor: Paraskevi Kyriaki Monou, Anastasia Maria Mamaligka, Emmanuil K. Tzimtzimis, Dimitrios Tzetzis, Souzan Vergkizi-Nikolakaki, Ioannis S. Vizirianakis, Eleftherios G. Andriotis, Georgios K. Eleftheriadis, Dimitrios G. Fatouros

Publikováno v: Pharmaceutics, Vol 14, Iss 8, p 1637 (2022)

In this study, drug carrier nanoparticles comprised of Pluronic-F127 and cannabidiol (CBD) or cannabigerol (CBG) were developed, and their wound healing action was studied. They were further incorporated in 3D printed films based on sodium alginate.

Externí odkaz: https://doaj.org/article/a67daff89a6349a5827928f77a789c28

Development of Bio-Active Patches Based on Pectin for the Treatment of Ulcers and Wounds Using 3D-Bioprinting Technology

Autor: Eleftherios G. Andriotis, Georgios K. Eleftheriadis, Christina Karavasili, Dimitrios G. Fatouros

Publikováno v: Pharmaceutics, Vol 12, Iss 1, p 56 (2020)

Biodegradable 3D-printable inks based on pectin have been developed as a system for direct and indirect wound-dressing applications, suitable for 3D printing technologies. The 3D-printable inks formed free-standing transparent films upon drying, with

Externí odkaz: https://doaj.org/article/d66becc604504ef3975486a972c9743a

FDM-printed pH-responsive capsules for the oral delivery of a model macromolecular dye

Autor: Sotirios Koutsopoulos, Christos S Katsiotis, Georgios K. Eleftheriadis, Nikolaos Bouropoulos, Dimitrios G. Fatouros

Publikováno v: Pharmaceutical Development and Technology. 25:517-523

To this day, the oral delivery of biomacromolecules remains a major developmentally-oriented challenge. A combinatorial approach was followed at this study, to formulate an efficient carrier for th...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fae1f4778ffab108b3cf5775c8e77b8
https://doi.org/10.1080/10837450.2019.1711396

Modular design principle based on compartmental drug delivery systems

Autor: Johan Boetker, Natalja Genina, Jukka Rantanen, Georgios K. Eleftheriadis

Publikováno v: Eleftheriadis, G K, Genina, N, Boetker, J & Rantanen, J 2021, ' Modular design principle based on compartmental drug delivery systems q ', Advanced Drug Delivery Reviews, vol. 178, 113921 . https://doi.org/10.1016/j.addr.2021.113921
Eleftheriadis, G K, Genina, N, Boetker, J & Rantanen, J 2021, ' Modular design principle based on compartmental drug delivery systems ', Advanced Drug Delivery Reviews, vol. 178, 113921 . https://doi.org/10.1016/j.addr.2021.113921

The current manufacturing solutions for oral solid dosage forms are fundamentally based on technologies from the 19th century. This approach is well suited for mass production of one-size-fits-all products; however, it does not allow for a straight-f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3359ad5d9ed377e4dab0b52a3a2b70ef
https://pubmed.ncbi.nlm.nih.gov/34390776

Development and Characterization of Inkjet Printed Edible Films for Buccal Delivery of B-Complex Vitamins

Autor: Paraskevi Kyriaki Monou, Nikoleta Moutafidou, Elisavet Mitsouli, Eleftherios G. Andriotis, Nikolaos Bouropoulos, Catherine K. Markopoulou, Dimitrios G. Fatouros, Georgios K. Eleftheriadis

Publikováno v: Pharmaceuticals
Volume 13
Issue 9
Pharmaceuticals, Vol 13, Iss 203, p 203 (2020)

Buccal films containing two vitamins, i.e., thiamine hydrochloride (THCl) and nicotinic acid (NA), were fabricated via two-dimensional (2D) inkjet printing. For the preparation of buccal films, solubility studies and rheological evaluations were cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47e0f9448129f9d44f33edcfe09d31b