Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Georgios Asimomitis"'
Autor:
Georgios Asimomitis, André G. Deslauriers, Andriana G. Kotini, Elsa Bernard, Davide Esposito, Malgorzata Olszewska, Nikolaos Spyrou, Juan Arango Ossa, Teresa Mortera-Blanco, Richard Koche, Yasuhito Nannya, Luca Malcovati, Seishi Ogawa, Mario Cazzola, Stuart A. Aaronson, Eva Hellström-Lindberg, Elli Papaemmanuil, Eirini P. Papapetrou
Publikováno v:
Blood Advances. 6:2992-3005
SF3B1K700E is the most frequent mutation in myelodysplastic syndrome (MDS), but the mechanisms by which it drives MDS pathogenesis remain unclear. We derived a panel of 18 genetically matched SF3B1K700E- and SF3B1WT-induced pluripotent stem cell (iPS
Autor:
Elli Papaemmanuil, Nai Kong V. Cheung, Scott A. Armstrong, Ross L. Levine, Ahmet Zehir, Andrew L. Kung, Shakeel Modak, Brian H. Kushner, Maria E. Arcilla, Kety H. Huberman, Neeman Mohibullah, Cassidy C. Cobbs, Georgios Asimomitis, Minal A. Patel, Yangyu Zhou, Noushin Farnoud, Kelly L. Bolton, Ryan N. Ptashkin, Yi Feng, Juan S. Medina-Martínez, Yanming Zhang, Max F. Levine, Teng Gao, Irene Y. Cheung, Juan E. Arango Ossa, Nathan E. Millard, Erin M. McGovern, Gunes Gundem, Kayleigh D. Rutherford, Barbara Spitzer
Supplementary Data from Bone Marrow Surveillance of Pediatric Cancer Survivors Identifies Clones that Predict Therapy-Related Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f498730950610964fb8c950585b0bbe
https://doi.org/10.1158/1078-0432.22481987.v1
https://doi.org/10.1158/1078-0432.22481987.v1
Autor:
Elli Papaemmanuil, Nai Kong V. Cheung, Scott A. Armstrong, Ross L. Levine, Ahmet Zehir, Andrew L. Kung, Shakeel Modak, Brian H. Kushner, Maria E. Arcilla, Kety H. Huberman, Neeman Mohibullah, Cassidy C. Cobbs, Georgios Asimomitis, Minal A. Patel, Yangyu Zhou, Noushin Farnoud, Kelly L. Bolton, Ryan N. Ptashkin, Yi Feng, Juan S. Medina-Martínez, Yanming Zhang, Max F. Levine, Teng Gao, Irene Y. Cheung, Juan E. Arango Ossa, Nathan E. Millard, Erin M. McGovern, Gunes Gundem, Kayleigh D. Rutherford, Barbara Spitzer
Supplementary Figure from Bone Marrow Surveillance of Pediatric Cancer Survivors Identifies Clones that Predict Therapy-Related Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c2fbac70b9b018d7b324fcd0b7264d
https://doi.org/10.1158/1078-0432.22481963
https://doi.org/10.1158/1078-0432.22481963
Autor:
Gunes Gundem, Max F. Levine, Stephen S. Roberts, Irene Y. Cheung, Juan S. Medina-Martínez, Yi Feng, Juan E. Arango-Ossa, Loic Chadoutaud, Mathieu Rita, Georgios Asimomitis, Joe Zhou, Daoqi You, Nancy Bouvier, Barbara Spitzer, David B. Solit, Filemon Dela Cruz, Michael P. LaQuaglia, Brian H. Kushner, Shakeel Modak, Neerav Shukla, Christine A. Iacobuzio-Donahue, Andrew L. Kung, Nai-Kong V. Cheung, Elli Papaemmanuil
High-risk neuroblastoma is generally metastatic and often lethal. Using genomic profiling of 470 sequential and spatially separated samples from 283 patients, we characterize subtype-specific genetic evolutionary trajectories from diagnosis, through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c93721c40b8e6e26b4ff6a26d4233ef
https://doi.org/10.1101/2022.08.15.503973
https://doi.org/10.1101/2022.08.15.503973
Autor:
Dylan Domenico, Gunes Gundem, Max F. Levine, Juanes E. Arango-Ossa, Pauline Robbe, Georgios Asimomitis, Cassidy Cobbs, Emily Stockfisch, Janine Senz, Dawn Cochrane, Neeman Mohibullah, Neerav Shukla, Sohrab P. Shah, Andrew McPherson, Anna Schuh, Andrew L. Kung, Elli Papaemmanuil
Publikováno v:
Cancer Research. 83:3142-3142
Whole genome sequencing (WGS) enables the identification of all cancer associated biomarkers in a patient’s tumor genome. Whilst fresh frozen (FF) derived WGS data provides optimal data quality, the majority of clinical biospecimens are from formal
Publikováno v:
Theoretical Population Biology, 131
Phylogenetic comparative methods (PCMs) have been used to study the evolution of quantitative traits in various groups of organisms, ranging from micro-organisms to animal and plant species. A common approach has been to assume a Gaussian phylogeneti
Autor:
Barbara Spitzer, Kayleigh D. Rutherford, Gunes Gundem, Erin M. McGovern, Nathan E. Millard, Juan E. Arango Ossa, Irene Y. Cheung, Teng Gao, Max F. Levine, Yanming Zhang, Juan S. Medina-Martínez, Yi Feng, Ryan N. Ptashkin, Kelly L. Bolton, Noushin Farnoud, Yangyu Zhou, Minal A. Patel, Georgios Asimomitis, Cassidy C. Cobbs, Neeman Mohibullah, Kety H. Huberman, Maria E. Arcilla, Brian H. Kushner, Shakeel Modak, Andrew L. Kung, Ahmet Zehir, Ross L. Levine, Scott A. Armstrong, Nai Kong V. Cheung, Elli Papaemmanuil
Publikováno v:
Clin Cancer Res
Purpose: Therapy-related myelodysplastic syndrome and acute leukemias (t-MDS/AL) are a major cause of nonrelapse mortality among pediatric cancer survivors. Although the presence of clonal hematopoiesis (CH) in adult patients at cancer diagnosis has