Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Georgios A. Keliris"'
Autor:
Sam De Waegenaere, Monica van den Berg, Georgios A. Keliris, Mohit H. Adhikari, Marleen Verhoye
Publikováno v:
Frontiers in Human Neuroscience, Vol 18 (2024)
IntroductionAlzheimer's disease (AD) is a progressive neurodegenerative disease resulting in memory loss and cognitive decline. Synaptic dysfunction is an early hallmark of the disease whose effects on whole-brain functional architecture can be ident
Externí odkaz:
https://doaj.org/article/dfe08d19bdef4c3d861c304ca910d049
Autor:
Mohit H. Adhikari, Tamara Vasilkovska, Roger Cachope, Haiying Tang, Longbin Liu, Georgios A. Keliris, Ignacio Munoz-Sanjuan, Dorian Pustina, Annemie Van der Linden, Marleen Verhoye
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Huntington’s disease (HD) is a neurodegenerative disorder caused by expanded (≥ 40) glutamine-encoding CAG repeats in the huntingtin gene, which leads to dysfunction and death of predominantly striatal and cortical neurons. While the gen
Externí odkaz:
https://doaj.org/article/35a3c24ce24144dab776a39042ce305a
Autor:
Faraz Moradi, Monica van den Berg, Morteza Mirjebreili, Lauren Kosten, Marleen Verhoye, Mahmood Amiri, Georgios A. Keliris
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107454- (2023)
Summary: The hippocampus plays a vital role in navigation, learning, and memory, and is affected in Alzheimer’s disease (AD). This study investigated the classification of AD-transgenic rats versus wild-type littermates using electrophysiological a
Externí odkaz:
https://doaj.org/article/81df3e93c7ab4ea68a96564a747326ed
Autor:
Inès R. H. Ben-Nejma, Aneta J. Keliris, Verdi Vanreusel, Peter Ponsaerts, Annemie Van der Linden, Georgios A. Keliris
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2023)
Abstract Background Alzheimer’s disease (AD) is an incurable neurodegenerative disorder characterised by the progressive buildup of toxic amyloid-beta (Aβ) and tau protein aggregates eventually leading to cognitive decline. Recent lines of evidenc
Externí odkaz:
https://doaj.org/article/17ed7e61b59449a2beb5f9ce5bc052fc
Autor:
Monica van den Berg, Mohit H. Adhikari, Marlies Verschuuren, Isabel Pintelon, Tamara Vasilkovska, Johan Van Audekerke, Stephan Missault, Loran Heymans, Peter Ponsaerts, Winnok H. De Vos, Annemie Van der Linden, Georgios A. Keliris, Marleen Verhoye
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-21 (2022)
Abstract Background Imbalanced synaptic transmission appears to be an early driver in Alzheimer’s disease (AD) leading to brain network alterations. Early detection of altered synaptic transmission and insight into mechanisms causing early synaptic
Externí odkaz:
https://doaj.org/article/f5f8e0376a9e4e1e8fae067453091d23
Autor:
Nima Salimi-Nezhad, Stephan Missault, Anaïs Notario-Reinoso, Atefe Hassani, Mahmood Amiri, Georgios A. Keliris
Publikováno v:
Neurobiology of Disease, Vol 180, Iss , Pp 106052- (2023)
Alzheimer's disease (AD) is a neurodegenerative disorder with a rising socioeconomic impact on societies. The hippocampus (HPC), which plays an important role in AD, is affected in the early stages. The medial septum (MS) in the forebrain provides ma
Externí odkaz:
https://doaj.org/article/4f501b23ab564f06a5993912d8c61b8b
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Alzheimer’s disease (AD) is a severe neurodegenerative disorder caused by the accumulation of toxic proteins, amyloid-beta (Aβ) and tau, which eventually leads to dementia. Disease-modifying therapies are still lacking, due to incomplete insights
Externí odkaz:
https://doaj.org/article/6931e74a6c884b87892ab829b03e5da6
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/6bdc79ecf3ce43339375df9f44fd8b2d
Autor:
Athena Demertzi, Aaron Kucyi, Adrián Ponce-Alvarez, Georgios A. Keliris, Susan Whitfield-Gabrieli, Gustavo Deco
Publikováno v:
Network Neuroscience, Vol 6, Iss 4, Pp 998-1009 (2022)
AbstractSpontaneous brain activity changes across states of consciousness. A particular consciousness-mediated configuration is the anticorrelations between the default mode network and other brain regions. What this antagonistic organization implies
Externí odkaz:
https://doaj.org/article/a65e6795f4034cde8c976efbaf8e444c
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
One of the main challenges in brain research is to link all aspects of brain function: on a cellular, systemic, and functional level. Multimodal neuroimaging methodology provides a continuously evolving platform. Being able to combine calcium imaging
Externí odkaz:
https://doaj.org/article/55dd05bcc7c64f0a89d61193f8d77536