Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Georgina V. Bixler"'
Autor:
Colleen A. Mangold, Benjamin Wronowski, Mei Du, Dustin R. Masser, Niran Hadad, Georgina V. Bixler, Robert M. Brucklacher, Matthew M. Ford, William E. Sonntag, Willard M. Freeman
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-19 (2017)
Abstract Background The necessity of including both males and females in molecular neuroscience research is now well understood. However, there is relatively limited basic biological data on brain sex differences across the lifespan despite the diffe
Externí odkaz:
https://doaj.org/article/8ff50482fdfc4d15be815b02c6ed9c50
Autor:
Heather D VanGuilder, Georgina V Bixler, Lydia Kutzler, Robert M Brucklacher, Sarah K Bronson, Scot R Kimball, Willard M Freeman
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16271 (2011)
BACKGROUND: As a leading cause of adult blindness, diabetic retinopathy is a prevalent and profound complication of diabetes. We have previously reported duration-dependent changes in retinal vascular permeability, apoptosis, and mRNA expression with
Externí odkaz:
https://doaj.org/article/21068942c8e34a8f8a9a343ee2866307
Autor:
Kent E. Vrana, Caesar G. Imperio, Ashley J. McFalls, Willard M. Freeman, Georgina V. Bixler, Patricia S. Grigson
Publikováno v:
Brain Research Bulletin. 123:81-93
One of the most damaging aspects of drug addiction is the degree to which natural rewards (family, friends, employment) are devalued in favor of seeking, obtaining and taking drugs. We have utilized an animal model of reward devaluation and heroin se
Autor:
Dustin R. Masser, Matthew M. Ford, Aditya Pisupati, David R. Stanford, Cory B. Giles, William E. Sonntag, Colleen A. Mangold, Georgina V. Bixler, Jonathan D. Wren, Willard M. Freeman
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 72:16-29
The major histocompatibility complex I (MHCI) pathway, which canonically functions in innate immune viral antigen presentation and detection, is functionally pleiotropic in the central nervous system (CNS). Alternative roles include developmental syn
Autor:
Patricia S. Grigson, David R. Stanford, Willard M. Freeman, Dustin R. Masser, Alissa A. Coffey, Kent E. Vrana, Niran Hadad, Georgina V. Bixler, Laura Blanco-Berdugo, Caesar G. Imperio, Elizabeth M. Colechio, Ashley J. McFalls
Environmental factors profoundly affect the addictive potential of drugs of abuse and may also modulate the neuro-anatomical/neuro-chemical impacts of uncontrolled drug use and relapse propensity. This study examined the impact of environmental enric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7ba14646e8829af3c69c778718fa3b
https://europepmc.org/articles/PMC6067959/
https://europepmc.org/articles/PMC6067959/
Autor:
Georgina V. Bixler, Jonathan D. Wren, Han Yan, Willard M. Freeman, Cory B. Giles, William E. Sonntag, Dustin R. Masser, Robert M. Brucklacher
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 69:1311-1324
Impairment of hippocampal-dependent spatial learning and memory with aging affects a large segment of the aged population. Hippocampal subregions (CA1, CA3, and DG) have been previously reported to express both common and specific morphological, func
Publikováno v:
Cellular and Molecular Neurobiology. 33:483-488
The myelin-associated inhibitor/Nogo-66 receptor 1 (NgR1) pathway directly functions in negative modulation of structural and electrophysiological synaptic plasticity. A previous study has established an important role of NgR1 pathway signaling in co
Autor:
Matthew M. Ford, Niran Hadad, Colleen A. Mangold, Mei Rong Du, Benjamin Wronowski, William E. Sonntag, Dustin R. Masser, Willard M. Freeman, Robert M. Brucklacher, Georgina V. Bixler
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-19 (2017)
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-19 (2017)
Background The necessity of including both males and females in molecular neuroscience research is now well understood. However, there is relatively limited basic biological data on brain sex differences across the lifespan despite the differences in
Autor:
Junie P. Warrington, Vijay P. Kale, Jacob M. Serfass, Colleen A. Van Kirk, Willard M. Freeman, Matthew Mitschelen, Julie A. Farley, Heather D. VanGuilder Starkey, Song Han, Georgina V. Bixler, William E. Sonntag, Caesar G. Imperio, Han Yan
Publikováno v:
Journal of Molecular Neuroscience. 48:111-126
The hippocampus undergoes changes with aging that impact neuronal function, such as synapse loss and altered neurotransmitter release. Nearly half of the aged population also develops deficits in spatial learning and memory. To identify age-related h
Publikováno v:
Journal of Neurochemistry. 121:77-98
Impairment of cognitive functions including hippocampus-dependent spatial learning and memory affects nearly half of the aged population. Age-related cognitive decline is associated with synaptic dysfunction that occurs in the absence of neuronal cel