Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Georgina K, Goddard"'
Autor:
Alexander Nestor-Bergmann, Georgina A. Stooke-Vaughan, Georgina K. Goddard, Tobias Starborg, Oliver E. Jensen, Sarah Woolner
Publikováno v:
Cell Reports, Vol 26, Iss 8, Pp 2088-2100.e4 (2019)
Summary: Distinct mechanisms involving cell shape and mechanical force are known to influence the rate and orientation of division in cultured cells. However, uncoupling the impact of shape and force in tissues remains challenging. Combining stretchi
Externí odkaz:
https://doaj.org/article/f0ab41da2cbe4c4e849d86d8fff401b8
Publikováno v:
SSRN Electronic Journal.
SUMMARYEpithelial tissues are highly sensitive to anisotropies in mechanical force, with cells altering fundamental behaviours such as cell adhesion, migration and cell division [1-5]. It is well known that in the later stages of carcinoma (epithelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d8aa0b38188e4e00ae97bdb1c8d4d1
https://doi.org/10.2139/ssrn.3624473
https://doi.org/10.2139/ssrn.3624473
Publikováno v:
Cold Spring Harbor protocols. 2020(3)
Over many years, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56cac7b19370299aa8225c6b7595cf2d
https://pubmed.ncbi.nlm.nih.gov/31857437
https://pubmed.ncbi.nlm.nih.gov/31857437
Autor:
Oliver E. Jensen, Tobias Starborg, Alexander Nestor-Bergmann, Sarah Woolner, Georgina A. Stooke-Vaughan, Georgina K. Goddard
Publikováno v:
Cell Reports, Vol 26, Iss 8, Pp 2088-2100.e4 (2019)
Cell Reports
Nestor-Bergmann, A, Stooke-Vaughan, G, Goddard, G, Starborg, T, Jensen, O & Woolner, S 2019, ' Decoupling the roles of cell shape and mechanical stress in orienting and cueing epithelial mitosis ', Cell Reports, vol. 26, no. 8, pp. 2088-2100 . https://doi.org/10.1016/j.celrep.2019.01.102
Cell Reports
Nestor-Bergmann, A, Stooke-Vaughan, G, Goddard, G, Starborg, T, Jensen, O & Woolner, S 2019, ' Decoupling the roles of cell shape and mechanical stress in orienting and cueing epithelial mitosis ', Cell Reports, vol. 26, no. 8, pp. 2088-2100 . https://doi.org/10.1016/j.celrep.2019.01.102
Summary Distinct mechanisms involving cell shape and mechanical force are known to influence the rate and orientation of division in cultured cells. However, uncoupling the impact of shape and force in tissues remains challenging. Combining stretchin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24df8151327ea913ebb4046a34a6e667
https://www.repository.cam.ac.uk/handle/1810/292178
https://www.repository.cam.ac.uk/handle/1810/292178
Autor:
Megan Moruzzi, Keith Brennan, Alexander Nestor-Bergmann, Sarah Woolner, Nawseen Tarannum, Georgina K. Goddard
Publikováno v:
Current Biology
Summary Epithelial tissues are highly sensitive to anisotropies in mechanical force, with cells altering fundamental behaviors, such as cell adhesion, migration, and cell division.1, 2, 3, 4, 5 It is well known that, in the later stages of carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc808fdcae053356dceca0352296daeb
http://europepmc.org/articles/PMC8360906
http://europepmc.org/articles/PMC8360906
Publikováno v:
Cold Spring Harbor Protocols. 2020:pdb.prot105551
Over many years, the Xenopus laevis embryo has provided a powerful model system to investigate how mechanical forces regulate cellular function. Here, we describe a system to apply reproducible tensile and compressive force to X. laevis animal cap ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4517f446d9fed1132c60490a61e3915
https://doi.org/10.1101/pdb.prot105551
https://doi.org/10.1101/pdb.prot105551
Publikováno v:
Journal of Cell Science. 131
Dynamic Cell III, a meeting jointly organized by the British Society of Cell Biology (BSCB) and the Biochemical Society, took place at the Manchester Conference Centre, Manchester, UK in March 2018. It brought together a diverse group of scientists f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07eaecb55b71b3bf73f3a8be9ed6449d
https://doi.org/10.1242/jcs.222927
https://doi.org/10.1242/jcs.222927
Autor:
Alexander Nestor-Bergmann, Sarah Woolner, Georgina K. Goddard, Georgina A. Stooke-Vaughan, Tobias Starborg, Oliver E. Jensen
Distinct mechanisms involving cell shape and mechanical force are known to influence the rate and orientation of division in cultured cells. However, uncoupling the impact of shape and force in tissues remains challenging. Combining stretching ofXeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d6069bc81762f008af0c76dca4c779
Autor:
Anna K. Salter, Philip G. Woodman, Victoria J. Allan, Sarah Woolner, Peter T Ruane, Georgina K. Goddard, Laura A. Jones, Nancy Papalopulu, Toby Starborg, Cécile Villemant
Publikováno v:
The Journal of Cell Biology
Cytoplasmic dynein light intermediate chains are required for the maintenance of centriole cohesion and the formation of a bipolar spindle in both human cells and Xenopus embryos.
Cytoplasmic dynein 1 (dynein) is a minus end–directed microtubu
Cytoplasmic dynein 1 (dynein) is a minus end–directed microtubu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6217e38cc55d6866e3c8c7cbe066d455
https://doi.org/10.1083/jcb.201408025
https://doi.org/10.1083/jcb.201408025
Publikováno v:
Seminars in Cell & Developmental Biology
The mechanical environment of a cell has a profound effect on its behaviour, from dictating cell shape to driving the transcription of specific genes. Recent studies have demonstrated that mechanical forces play a key role in orienting the mitotic sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010540a9924223633203f9015687a297