Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Georgina E T Blake"'
Autor:
Eilis Hannon, Emma L. Dempster, Jonathan P. Davies, Barry Chioza, Georgina E. T. Blake, Joe Burrage, Stefania Policicchio, Alice Franklin, Emma M. Walker, Rosemary A. Bamford, Leonard C. Schalkwyk, Jonathan Mill
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Due to interindividual variation in the cellular composition of the human cortex, it is essential that covariates that capture these differences are included in epigenome-wide association studies using bulk tissue. As experimental
Externí odkaz:
https://doaj.org/article/3d312550f3bb4808b28fa6884c2ceea6
Autor:
Georgina E. T. Blake, Xiaohui Zhao, Hong wa Yung, Graham J. Burton, Anne C. Ferguson-Smith, Russell S. Hamilton, Erica D. Watson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Abnormal folate metabolism in mice results in transgenerational epigenetic inheritance of congenital malformations. Here, the authors provide evidence that defective folate metabolism causes germline epigenetic instability and observe multigeneration
Externí odkaz:
https://doaj.org/article/a2b6f87964694b4bad4140b486ce7efe
Autor:
Colleen Geary Joo, Georgina E T Blake, Malwina Prater, Erica D. Watson, Russell S. Hamilton, Katerina Menelaou, Simon James Tunster, James C. Cross
Publikováno v:
Reproduction (Cambridge, England)
Assisted reproduction technologies (ARTs) are becoming increasingly common. Therefore, how these procedures influence gene regulation and foeto-placental development are important to explore. Here, we assess the effects of blastocyst transfer on mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7472aa618f3e1b230b572121cce42481
https://pubmed.ncbi.nlm.nih.gov/31751309
https://pubmed.ncbi.nlm.nih.gov/31751309
Autor:
Tessa M, Bertozzi, Jessica L, Becker, Georgina E T, Blake, Amita, Bansal, Duy K, Nguyen, Denise S, Fernandez-Twinn, Susan E, Ozanne, Marisa S, Bartolomei, Rebecca A, Simmons, Erica D, Watson, Anne C, Ferguson-Smith
Publikováno v:
Nature genetics. 53(8)
The agouti viable yellow (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f77bdd8c8d8ed5b47d144d1def9722db
https://pubmed.ncbi.nlm.nih.gov/34326546
https://pubmed.ncbi.nlm.nih.gov/34326546
Autor:
Nisha, Padmanabhan, Katerina, Menelaou, Jiali, Gao, Alexander, Anderson, Georgina E T, Blake, Tanya, Li, B Nuala, Daw, Erica D, Watson
Publikováno v:
The Journal of Physiology
Key points Folate (folic acid) deficiency and mutations in folate‐related genes in humans result in megaloblastic anaemia.Folate metabolism, which requires the enzyme methionine synthase reductase (MTRR), is necessary for DNA synthesis and the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42c9d7cb52038ca454335ba9e7013bd7
https://pubmed.ncbi.nlm.nih.gov/30024025
https://pubmed.ncbi.nlm.nih.gov/30024025
Elucidating how the environment affects human health will further our understanding of disease risk and prevention, and adaptation. Recent evidence reveals that exposure to environmental stressors in our lifetime might affect disease risk in our desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c08031ddc20fd5151ffe46db952c0f12
https://doi.org/10.1016/b978-0-12-812215-0.00026-1
https://doi.org/10.1016/b978-0-12-812215-0.00026-1
Autor:
Georgina E T Blake, Erica D. Watson
Publikováno v:
Current opinion in chemical biology. 33
There are numerous benefits to elucidating how our environment affects our health: from a greater understanding of adaptation to disease prevention. Evidence shows that stressors we are exposed to during our lifetime might cause disease in our descen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ebfa86442032a1bdb84e80bd3565e28
https://pubmed.ncbi.nlm.nih.gov/27327212
https://pubmed.ncbi.nlm.nih.gov/27327212
Autor:
Hannon, Eilis1 (AUTHOR) E.J.Hannon@exeter.ac.uk, Dempster, Emma L.1 (AUTHOR), Davies, Jonathan P.1 (AUTHOR), Chioza, Barry1 (AUTHOR), Blake, Georgina E. T.1 (AUTHOR), Burrage, Joe1 (AUTHOR), Policicchio, Stefania2 (AUTHOR), Franklin, Alice1 (AUTHOR), Walker, Emma M.1 (AUTHOR), Bamford, Rosemary A.1 (AUTHOR), Schalkwyk, Leonard C.3 (AUTHOR), Mill, Jonathan1 (AUTHOR)
Publikováno v:
BMC Biology. 1/25/2024, Vol. 22 Issue 1, p1-19. 19p.
Autor:
Marisa S. Bartolomei, Jessica L. Becker, Anne C. Ferguson-Smith, Rebecca A. Simmons, Erica D. Watson, Georgina E T Blake, Tessa M. Bertozzi, Amita Bansal, Duy Nguyen, Susan E. Ozanne, Denise S. Fernandez-Twinn
Publikováno v:
Nature Genetics
The agouti viable yellow (Avy) allele is an insertional mutation in the mouse genome caused by a variably methylated intracisternal A particle (VM-IAP) retrotransposon. Avy expressivity is sensitive to a range of early-life chemical exposures and nut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7deb4475fa9b404ba35e34e41ef6dae5
Publikováno v:
Reproduction, Fertility & Development; 2019, Vol. 31 Issue 11, p1730-1741, 12p