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pro vyhledávání: '"Georgina C. B. Nicholl"'
Publikováno v:
British Journal of Pharmacology. 174:781-795
BACKGROUND AND PURPOSE Ionotropic GABA receptors are evolutionarily conserved proteins that mediate cellular and network inhibition in both vertebrates and invertebrates. A unique class of excitatory GABA receptors has been identified in several nema
Publikováno v:
Journal of Visualized Experiments.
The clustered regularly interspersed palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9) prokaryotic adaptive immune defense system has been co-opted as a powerful tool for precise eukaryotic genome engineering. Here, we present a rapid a
Publikováno v:
British journal of pharmacology. 174(9)
Ionotropic GABA receptors are evolutionarily conserved proteins that mediate cellular and network inhibition in both vertebrates and invertebrates. A unique class of excitatory GABA receptors has been identified in several nematode species. Despite w
Autor:
Dafna Bonneh-Barkay, Premeela A. Rajakumar, Rafael Medina-Flores, Robert Bowser, Stephanie J. Bissel, Kenneth N. Fish, Julia Nyaundi, Gouji Wang, Michael Murphey-Corb, John W. Mellors, Samuel W. Darko, Clayton A. Wiley, Georgina C. B. Nicholl
Publikováno v:
The American Journal of Pathology. 173:130-143
Human immunodeficiency virus encephalitis causes dementia in acquired immune deficiency syndrome patients. Using proteomic analysis of postmortem cerebrospinal fluid (CSF) and brain tissue from the simian immunodeficiency virus primate model, we demo
Axonal guidance involves extrinsic molecular cues that bind growth cone receptors and signal to the cytoskeleton through divergent pathways. Some signaling intermediates are deployed downstream of molecularly distinct axon guidance receptor families,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231576a24b8f81527a542dd3bd1fa044
https://europepmc.org/articles/PMC6605621/
https://europepmc.org/articles/PMC6605621/
Autor:
Anna Polshyna, James Lyons-Weiler, Georgina C. B. Nicholl, Robert Bowser, Srikanth Ranganathan
Publikováno v:
Clinical proteomics. 2(1-2)
Recent studies have evaluated proper acquisition and storage procedures for the use of serum or plasma for mass spectrometry (MS)-based proteomics. The present study examines the proteome stability of human cerebrospinal fluid (CSF) over time at 23°
Autor:
Robert Bowser, Fran Lutka, Srikanth Ranganathan, Ramasri Sathanoori, David Lacomis, Sarah Henry, Georgina C. B. Nicholl
Publikováno v:
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. 8(6)
Neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), lack definitive diagnostic tests or biomarkers of disease progression. Most studies that investigate protein abnormalities in ALS have used biofluids such as blood or cerebros