Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Georgina Berrozpe"'
Publikováno v:
Cell Reports, Vol 20, Iss 7, Pp 1585-1596 (2017)
SOX2 and OCT4, in conjunction with KLF4 and cMYC, are sufficient to reprogram human fibroblasts to induced pluripotent stem cells (iPSCs), but it is unclear if they function as transcriptional activators or as repressors. We now show that, like OCT4,
Externí odkaz:
https://doaj.org/article/5994a6cac86a4e1f93a10f3041e6dab9
Autor:
Georgina Berrozpe, Gene O. Bryant, Katherine Warpinski, Dan Spagna, Santosh Narayan, Shivangi Shah, Mark Ptashne
Publikováno v:
Cell Reports, Vol 20, Iss 4, Pp 785-793 (2017)
How is Polycomb (Pc), a eukaryotic negative regulator of transcription, targeted to specific mammalian genes? Our genome-wide analysis of the Pc mark H3K27me3 in murine cells revealed that Pc is preferentially associated with CpG island promoters of
Externí odkaz:
https://doaj.org/article/7385f301de9a4ff1867367603739db4b
Publikováno v:
Cell Reports, Vol 4, Iss 3, Pp 445-453 (2013)
A quantitative nucleosome occupancy assay revealed rules for nucleosome disposition in yeast and showed how disposition affects regulation of the GAL genes. Here, we show how those findings apply to the control of Kit, a mammalian gene. The Kit promo
Externí odkaz:
https://doaj.org/article/1496789e7dd044fabc0e7710f439482a
Autor:
Gene O. Bryant, Dan Spagna, Georgina Berrozpe, Santosh Narayan, Shivangi Shah, Mark Ptashne, Katherine Warpinski
Publikováno v:
Cell Reports, Vol 20, Iss 4, Pp 785-793 (2017)
How is Polycomb (Pc), a eukaryotic negative regulator of transcription, targeted to specific mammalian genes? Our genome-wide analysis of the Pc mark H3K27me3 in murine cells that revealed Pc is preferentially associated with CpG island promoters of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad6144a9f878bd2e5a8f45b92c08ecb
http://www.sciencedirect.com/science/article/pii/S2211124717309075
http://www.sciencedirect.com/science/article/pii/S2211124717309075
Publikováno v:
Cell Reports, Vol 20, Iss 7, Pp 1585-1596 (2017)
SOX2 and OCT4, in conjunction with KLF4 and cMYC, are sufficient to reprogram human fibroblasts to induced pluripotent stem cells (iPSCs), but it is unclear if they function as transcriptional activators or as repressors. We now show that, like OCT4,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb19928e4894a57330002aeb1d9d2ff8
https://europepmc.org/articles/PMC5648000/
https://europepmc.org/articles/PMC5648000/
Autor:
Georgina Berrozpe, Benedikt Bosbach, Katherine Warpinski, Imke Ehlers, Darren R. Veach, Andrew Kwok, Jennifer K. Loo, Yasemin Yozgat, Cristina R. Antonescu, Ronald P. DeMatteo, Jennifer Q. Zhang, Ferdinand Rossi, Katia Manova, Peter Besmer
WOS: 000412130500018 PubMed ID: 28923937 Gastrointestinal stromal tumors (GISTs) predominantly harbor activating mutations in the receptor tyrosine kinase KIT. To genetically dissect in vivo the requirement of different signal transduction pathways e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f458e1c6aa729c98f9d662df0ce40fb
https://hdl.handle.net/20.500.12511/3705
https://hdl.handle.net/20.500.12511/3705
Autor:
Georgina Berrozpe, Steven Yukl, Youichi Tajima, Masao Ono, Peter Besmer, Inna Timokhina, Andrew D. Zelenetz
Publikováno v:
Blood. 94:2658-2666
The Kit and PDGFRa receptor tyrosine kinases are encoded in close proximity at the murine white spotting (W) and patch (Ph) loci. Whereas W mutations affect hematopoiesis, melanogenesis, and gametogenesis, the Ph mutation affects melanogenesis and ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cdf3ff82b74a9d245e8c16fcd70c186
https://doi.org/10.1182/blood.v94.8.2658.420k23_2658_2666
https://doi.org/10.1182/blood.v94.8.2658.420k23_2658_2666
Autor:
Georgina Berrozpe, Estanis Navarro, Montserrat Torà, Francisco X. Real, Teresa Adell, Lluis Espinosa
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1450(3):254-264
To study the mechanisms that control epithelial commitment and differentiation we have used undifferentiated HT-29 colon cancer cells and a subpopulation of mucus secreting cells obtained by selection of HT-29 cells in 10−6 M methotrexate (M6 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe2b72533013927a3fe0be06a8eae2e
Publikováno v:
Cell Reports, Vol 4, Iss 3, Pp 445-453 (2013)
Summary A quantitative nucleosome occupancy assay revealed rules for nucleosome disposition in yeast and showed how disposition affects regulation of the GAL genes. Here, we show how those findings apply to the control of Kit , a mammalian gene. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228eee92e5dc11f72d7f1c4a4b3e8417
https://pubmed.ncbi.nlm.nih.gov/23911283
https://pubmed.ncbi.nlm.nih.gov/23911283
Autor:
Peter Besmer, Valter Agosti, Georgina Berrozpe, Christine M. Tucker, Katia Manova, Cédric Blanpain
Publikováno v:
Molecular and cellular biology. 26(15)
The Kit receptor tyrosine kinase functions in hematopoiesis, melanogenesis, and gametogenesis and in interstitial cells of Cajal. We previously identified two upstream hypersensitive site (HS) clusters in mast cells and melanocytes. Here we investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e555817605ec61bff80de4fa363a0ec
https://pubmed.ncbi.nlm.nih.gov/16847336
https://pubmed.ncbi.nlm.nih.gov/16847336