Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Georgii Bazykin"'
Publikováno v:
eLife, Vol 12 (2023)
SARS-CoV-2 has adapted in a stepwise manner, with multiple beneficial mutations accumulating in a rapid succession at origins of VOCs, and the reasons for this are unclear. Here, we searched for coordinated evolution of amino acid sites in the spike
Externí odkaz:
https://doaj.org/article/d284c98a0ef448bcb640456d080e4fae
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144388 (2015)
Splice sites (SSs)--short nucleotide sequences flanking introns--are under selection for spliceosome binding, and adhere to consensus sequences. However, non-consensus nucleotides, many of which probably reduce SS performance, are frequent. Little is
Externí odkaz:
https://doaj.org/article/6868ec5ebb594141a01448256a4a0563
Publikováno v:
Molecular Biology and Evolution. 39
Insertions and deletions of lengths not divisible by 3 in protein-coding sequences cause frameshifts that usually induce premature stop codons and may carry a high fitness cost. However, this cost can be partially offset by a second compensatory inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e417768ed92ef6554b2d8b566c96c8a7
https://doi.org/10.1093/molbev/msac031
https://doi.org/10.1093/molbev/msac031
Publikováno v:
PLOS Computational Biology. 18:e1009878
Fitness conferred by the same allele may differ between genotypes and environments, and these differences shape variation and evolution. Changes in amino acid propensities at protein sites over the course of evolution have been inferred from sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c6f281797af4cffaeb106c4ec98a68
https://doi.org/10.1371/journal.pcbi.1009878
https://doi.org/10.1371/journal.pcbi.1009878
Autor:
Georgii Bazykin
Publikováno v:
Peer Community In Evolutionary Biology. :100080
A recommendation of: Marjolaine Rousselle, Paul Simion, Marie-Ka Tilak, Emeric Figuet, Benoit Nabholz, Nicolas Galtier Is adaptation limited by mutation? A timescale-dependent effect of genetic diversity on the adaptive substitution rate in animals 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36a662915597b58090a299bdf9b842dc
https://doi.org/10.24072/pci.evolbiol.100080
https://doi.org/10.24072/pci.evolbiol.100080
Autor:
Konstantin Popadin, Georgii Bazykin
Publikováno v:
Nature Precedings
Direct nucleotide repeats can facilitate deletions of segments of mitochondrial genome1, leading to a wide range of neuromuscular disorders1,2 as well as aging2,3 in humans. We hypothesized that the number of the direct perfect repeats in human mitoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______984::b90670279111b6bce9f9c27cfb303f7b
http://hdl.handle.net/10101/npre.2008.2399.1
http://hdl.handle.net/10101/npre.2008.2399.1
