Zobrazeno 1 - 10 of 73 pro vyhledávání: '"Georgianna G Gould"'
1
Akademický článek
Melanotan-II reverses autistic features in a maternal immune activation mouse model of autism.
Autor: Elena Minakova, Jordan Lang, Jesus-Servando Medel-Matus, Georgianna G Gould, Ashley Reynolds, Don Shin, Andrey Mazarati, Raman Sankar
Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0210389 (2019)
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impaired social interactions, difficulty with communication, and repetitive behavior patterns. In humans affected by ASD, there is a male pre-disposition towards
Externí odkaz: https://doaj.org/article/43cb744ac7694028aff4e1a3e689a839
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2
Akademický článek
Antidepressant-like drug effects in juvenile and adolescent mice in the tail suspension test: Relationship with hippocampal serotonin and norepinephrine transporter expression and function.
Autor: Nathan C Mitchell, Georgianna G Gould, Corey M Smolik, Wouter eKoek, Lynette C Daws
Publikováno v: Frontiers in Pharmacology, Vol 4 (2013)
Depression is a major health problem for which most patients are not effectively treated. This problem is further compounded in children and adolescents where only two antidepressants [both selective serotonin reuptake inhibitors (SSRIs)] are current
Externí odkaz: https://doaj.org/article/35c220d9373e4d0aa97f87a2596e3c5b
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3
Akademický článek
Acute cannabidiol treatment enhances social interaction in adult male mice
Autor: Livia F. Ferreira, Nikhita Pathapati, Stephen T. Schultz, Mary C. Nunn, Bethany L. Pierce, Yatzil R. Sanchez, Meredith D. Murrell, Brett C. Ginsburg, Emmanuel S. Onaivi, Georgianna G. Gould
Publikováno v: Advances in Drug and Alcohol Research, Vol 3 (2023)
Cannabidiol (CBD) is a non-intoxicating phytochemical from Cannabis sativa that is increasingly used to manage pain. The potential for CBD to ameliorate dimensional behavior symptoms occurring in multiple psychiatric disorders was suggested, includin
Externí odkaz: https://doaj.org/article/7820cb83509145e79b5dbeccc301b2f0
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4
High Affinity Decynium-22 Binding to Brain Membrane Homogenates and Reduced Dorsal Camouflaging after Acute Exposure to it in Zebrafish
Autor: Georgianna G, Gould, Priscilla A, Barba-Escobedo, Rebecca E, Horton, Lynette C, Daws
Publikováno v: Frontiers in Pharmacology. 13
Organic cation transporters (OCTs) are expressed in the mammalian brain, kidney, liver, placenta, and intestines, where they facilitate the transport of cations and other substrates between extracellular fluids and cells. Despite increasing reliance
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234013cebc08fb84557309b5d2459f5e
https://doi.org/10.3389/fphar.2022.841423
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7
Extreme enhancement or depletion of serotonin transporter function and serotonin availability in autism spectrum disorder
Autor: Lynette C. Daws, T. Lee Gilman, Georgianna G. Gould, Valentina R. Garbarino
Publikováno v: Pharmacological Research. 140:85-99
A variety of human and animal studies support the hypothesis that serotonin (5-hydroxytryptamine or 5-HT) system dysfunction is a contributing factor to the development of autism in some patients. However, many questions remain about how developmenta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b3193bfe6b5106c7f236fdcb60bd82
https://doi.org/10.1016/j.phrs.2018.07.010
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9
Endocannabinoid System Dysregulation from Acetaminophen Use May Lead to Autism Spectrum Disorder: Could Cannabinoid Treatment Be Efficacious?
Autor: Nicola Antonucci, Anna Lisa Brigida, Stephen Schultz, Dario Siniscalco, Georgianna G. Gould
Publikováno v: Molecules
Molecules, Vol 26, Iss 1845, p 1845 (2021)
Persistent deficits in social communication and interaction, and restricted, repetitive patterns of behavior, interests or activities, are the core items characterizing autism spectrum disorder (ASD). Strong inflammation states have been reported to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06d61c26596a858dc05bdf55c0b586d
http://europepmc.org/articles/PMC8037883
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10
Developmental and behavioral effects in neonatal and adult mice following prenatal activation of endocannabinoid receptors by capsaicin
Autor: Georgianna G. Gould, Norman Schanz, Sonya M. Bierbower, Lauren Tyrell, Alex Perchuk, Neal Joshi, Emmanuel S. Onaivi, Zoila Mora, Ana Canseco-Alba
Publikováno v: Acta Pharmacologica Sinica. 40:418-424
Despite the apparent abundance of ligand-gated transient receptor potential vanilloid type 1 (TRPV1) and possible cross talk between the endocannabinoid and endovanilloid systems in the central nervous system (CNS), it is unclear what role TRPV1 rece
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6626817e217d6966db92147a4b56dde0
https://doi.org/10.1038/s41401-018-0073-z
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