Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Georgia Tsaouli"'
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Acute lymphoblastic leukemia (ALL) is the most common cancer among children. Recent advances in chemotherapy have made ALL a curable hematological malignancy. In children, there is 25% chance of disease relapse, typically in the central nervous syste
Externí odkaz:
https://doaj.org/article/302e7d8fafe147f5bd249636e85d2d7a
Autor:
Elisabetta Tortorella, Cleofe Palocci, Stefania Morrone, Francesco Brasili, Ida Silvestri, Fabio Domenici, Chiara D’Errico, Laura Chronopoulou, Federico Bordi, Georgia Tsaouli, Sabrina Giantulli
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 180:495-502
Doxorubicin (DOX) is commonly used to treat several tumor types, but its severe side effects, primarily cardiotoxicity, represent a major limitation for its use in clinical settings. In this study we developed and characterized biodegradable and stab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5690a5b4eb66c3a6b462fc664cfea943
https://doi.org/10.1016/j.colsurfb.2019.05.006
https://doi.org/10.1016/j.colsurfb.2019.05.006
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030364212
Notch is a ligand–receptor interaction-triggered signaling cascade highly conserved, that influences multiple lineage decisions within the hematopoietic and the immune system. It is a recognized model of intercellular communication that plays an es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdee9ae68be3246bbb547b8ae3bcdebe
https://doi.org/10.1007/978-3-030-36422-9_10
https://doi.org/10.1007/978-3-030-36422-9_10
Autor:
Luigi Frati, Georgia Tsaouli, Morteza Mahmoudi, Rossella Rota, Daniela Pozzi, Maria Antonietta Oliva, Giulio Caracciolo, Sara Palchetti, Anna Laura Capriotti, Luca Digiacomo, Isabella Screpanti, Antonietta Arcella
Publikováno v:
ACS chemical neuroscience. 9(12)
Temozolomide (TMZ) is the current first-line chemotherapy for treatment of glioblastoma multiforme (GBM). However, similar to other brain therapeutic compounds, access of TMZ to brain tumors is impaired by the blood-brain barrier (BBB) leading to poo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb069f85e656677706a3887c43365e75
https://pubmed.ncbi.nlm.nih.gov/30015470
https://pubmed.ncbi.nlm.nih.gov/30015470
Autor:
Francesca Ferrandino, Georgia Tsaouli, Giovanni Bernardini, Zein Mersini Besharat, Diana Bellavia, Antonio Francesco Campese, Ambra Ciuffetta, Alessandra Vacca, Isabella Screpanti, Claudia Noce, Maria Pia Felli, Paola Grazioli
Publikováno v:
Oncogene
Notch hyperactivation dominates T-cell acute lymphoblastic leukemia development, but the mechanisms underlying “pre-leukemic” cell dissemination are still unclear. Here we describe how deregulated Notch3 signaling enhances CXCR4 cell-surface expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8090ee41d59d75fd544a6eba9bc9ebe3
http://hdl.handle.net/11573/1119498
http://hdl.handle.net/11573/1119498
Autor:
Georgia Tsaouli, Isabella Screpanti, Saula Checquolo, Paola Grazioli, Giovanni Bernardini, Diana Bellavia, Antonio Francesco Campese, Francesca Ferrandino, Maria Pia Felli
Publikováno v:
ESMO Open. 3:A383-A384
Introduction Acute T-cell lymphoblastic leukaemia (T-ALL) is a childhood cancer, characterised by infiltration of immature T-cells in bone marrow. Notch hyperactivation is a major driver of T-ALL development where CXCL12/CXCR4 axis plays an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e5ced304ea29ba2707e4f5961cd2ed3
https://doi.org/10.1136/esmoopen-2018-eacr25.905
https://doi.org/10.1136/esmoopen-2018-eacr25.905