Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Georgia Makrypidi"'
Autor:
Morton Freytag, Martina Kluth, Elena Bady, Claudia Hube-Magg, Georgia Makrypidi-Fraune, Hans Heinzer, Doris Höflmayer, Sören Weidemann, Ria Uhlig, Hartwig Huland, Markus Graefen, Christian Bernreuther, Corinna Wittmer, Maria Christina Tsourlakis, Sarah Minner, David Dum, Andrea Hinsch, Andreas M. Luebke, Ronald Simon, Guido Sauter, Thorsten Schlomm, Katharina Möller
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Epithelial splicing regulatory protein 1 (ESRP1) and 2 (ESRP2) regulate alternative splicing events of various pre-mRNAs. Some of these targets play a role in cancer-associated processes, including cytoskeleton reorganization and
Externí odkaz:
https://doaj.org/article/db4ee428922443c8b565af13ce108bb1
Autor:
Wenchao Li, Niclas C. Blessin, Ronald Simon, Martina Kluth, Kristine Fischer, Claudia Hube-Magg, Georgia Makrypidi-Fraune, Björn Wellge, Tim Mandelkow, Nicolaus F. Debatin, Laura Pott, Doris Höflmayer, Maximilian Lennartz, Guido Sauter, Jakob R. Izbicki, Sarah Minner, Franziska Büscheck, Ria Uhlig, David Dum, Till Krech, Andreas M. Luebke, Corinna Wittmer, Frank Jacobsen, Eike Burandt, Stefan Steurer, Waldemar Wilczak, Andrea Hinsch
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Hodgkin’s lymphoma (HL) is characterized by a high background of inflammatory cells which play an important role for the pathogenesis of the disease. T cell immunoreceptor with Ig and ITIM domains (TIGIT) is an inhibitory immune checkpoint
Externí odkaz:
https://doaj.org/article/2b5a8c7c60d84f75a83d9a87293394bd
Autor:
Jessica Schmiesing, Stephan Storch, Ann-Cathrin Dörfler, Michaela Schweizer, Georgia Makrypidi-Fraune, Melanie Thelen, Marc Sylvester, Volkmar Gieselmann, Catherine Meyer-Schwesinger, Friedrich Koch-Nolte, Henning Tidow, Chris Mühlhausen, Abdul Waheed, William S. Sly, Thomas Braulke
Publikováno v:
Cell Reports, Vol 24, Iss 11, Pp 2946-2956 (2018)
Summary: Lysine glutarylation (Kglu) of mitochondrial proteins is associated with glutaryl-CoA dehydrogenase (GCDH) deficiency, which impairs lysine/tryptophan degradation and causes destruction of striatal neurons during catabolic crisis with subseq
Externí odkaz:
https://doaj.org/article/b3476a6f49174f2f967f25a8a25f0543
Autor:
Guido Sauter, Sarah Bonk, Ronald Simon, Katharina Möller, Doris Höflmayer, Thorsten Schlomm, Georgia Makrypidi-Fraune, Andrea Hinsch, Sebastian Dwertmann Rico, Pinar Tasdelen, Martina Kluth, Markus Graefen, Andreas M. Luebke, Hans Heinzer, Claudia Hube-Magg, Sarah Minner, Franziska Büscheck, Sören Weidemann, David Dum, Ria Uhlig
Publikováno v:
Pathology International. 70:733-742
B7-H3 is a member of the B7 superfamily of immune checkpoint molecules. B7-H3 up regulation has been linked to cancer development and progression in many tumors including prostate cancer. To clarify the potential utility of B7-H3 as a prognostic biom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a527be29276644c85b5488de73d2c1
https://doi.org/10.1111/pin.12999
https://doi.org/10.1111/pin.12999
Autor:
Stefan Steurer, Ronald Simon, Thorsten Schlomm, Anna Lena Wecker, Martina Kluth, Andreas M. Luebke, Doris Höflmayer, Sarah Minner, Hartwig Huland, Christoph Fraune, Hans Heinzer, Sören Weidemann, Andreas Marx, Waldemar Wilczak, Alexander Haese, Till S. Clauditz, Claudia Hube-Magg, Guido Sauter, Katharina Möller, Georgia Makrypidi-Fraune, Sarah Bonk, Christian Bernreuther
Publikováno v:
Virchows Archiv
Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) is a ubiquitous RNA splicing factor that is overexpressed and prognostically relevant in various human cancer types. To study the impact of hnRNPA1 expression in prostate cancer, we analyzed a tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b250226d6180db5fe49d37c01a826e
https://doi.org/10.1007/s00428-020-02834-4
https://doi.org/10.1007/s00428-020-02834-4
Autor:
Daniel Perez, Claudia Hube-Magg, Christoph Fraune, Guido Sauter, Franziska Büscheck, Jakob R. Izbicki, Fabrice Viol, Martina Kluth, Tania Amin, Till S. Clauditz, Georgia Makrypidi-Fraune, Wilfrid Fehrle, Doris Höflmayer, Ronald Simon, Eike Burandt, Jörg Schrader, Stefan Steurer, Waldemar Wilczak, David Dum
Publikováno v:
Endocrine Pathology
Neuroendocrine neoplasms comprise a heterogeneous group of tumors, categorized into neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs) depending on tumor differentiation. NECs and high-grade NETs (G3) confer a poor prognosis, demanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::858cc5e85313f8b75411736e9672badc
https://doi.org/10.1007/s12022-020-09612-7
https://doi.org/10.1007/s12022-020-09612-7
Autor:
Barbara Schmalfeldt, Claudia Hube-Magg, Eike Burandt, Stefan Steurer, Martina Kluth, Franziska Büscheck, Ronald Simon, Linn Wölber, Guido Sauter, Christian Wilke, Peter Paluchowski, Waldemar Wilczak, Doris Höflmayer, Till S. Clauditz, Janina Rosebrock, Volkmar Müller, Christoph Fraune, Ingo von Leffern, Georgia Makrypidi-Fraune, Isabell Witzel, Uwe Heilenkötter
Publikováno v:
Gynecologic Oncology. 156:669-675
Objective Mismatch repair (MMR) deficiency and Bethesda panel microsatellite instability (MSI) are increasingly analyzed to identify tumors that might benefit from immune checkpoint inhibitors, but tumor heterogeneity is a potential obstacle for such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7807a0ac629e5cfcd1b2bf698a461b8a
https://doi.org/10.1016/j.ygyno.2019.12.031
https://doi.org/10.1016/j.ygyno.2019.12.031
Autor:
Daniel Perez, Wenchao Li, Niclas Ch Blessin, Jakob R. Izbicki, Michael Neipp, Stefan Steurer, Thies Daniels, Tim Mandelkow, Doris Höflmayer, Claudia Hube-Magg, Ronald Simon, Waldemar Wilczak, Till S. Clauditz, Georgia Makrypidi-Fraune, Eike Burandt, Jörg Schrader, Christoph Fraune, Christoph Isbert, Franziska Büscheck, Guido Sauter, Martina Kluth, Hamid Mofid
Publikováno v:
Annals of Surgical Oncology
Background Microsatellite instability (MSI) has emerged as a predictive biomarker for immune checkpoint inhibitor therapy. Cancer heterogeneity represents a potential obstacle for the analysis of predicitive biomarkers. MSI has been reported in pancr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833bbd0e0c28c7d691b386ebb4bf7cbe
https://doi.org/10.1245/s10434-020-08209-y
https://doi.org/10.1245/s10434-020-08209-y
Autor:
Koenig, Alexandra M. Poos, Cornelia Schroeder, Neeraja Jaishankar, Daniela Röll, Marcus Oswald, Jan Meiners, Delia M. Braun, Caroline Knotz, Lukas Frank, Manuel Gunkel, Roman Spilger, Thomas Wollmann, Adam Polonski, Georgia Makrypidi-Fraune, Christoph Fraune, Markus Graefen, Inn Chung, Alexander Stenzel, Holger Erfle, Karl Rohr, Aria Baniahmad, Guido Sauter, Karsten Rippe, Ronald Simon, Rainer
Publikováno v:
Cancers; Volume 14; Issue 5; Pages: 1267
The current risk stratification in prostate cancer (PCa) is frequently insufficient to adequately predict disease development and outcome. One hallmark of cancer is telomere maintenance. For telomere maintenance, PCa cells exclusively employ telomera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::4e17f0a607da48ffcf306b0bd3d0b846
Autor:
Alexandra M, Poos, Cornelia, Schroeder, Neeraja, Jaishankar, Daniela, Röll, Marcus, Oswald, Jan, Meiners, Delia M, Braun, Caroline, Knotz, Lukas, Frank, Manuel, Gunkel, Roman, Spilger, Thomas, Wollmann, Adam, Polonski, Georgia, Makrypidi-Fraune, Christoph, Fraune, Markus, Graefen, Inn, Chung, Alexander, Stenzel, Holger, Erfle, Karl, Rohr, Aria, Baniahmad, Guido, Sauter, Karsten, Rippe, Ronald, Simon, Rainer, Koenig
Publikováno v:
Cancers. 14(5)
The current risk stratification in prostate cancer (PCa) is frequently insufficient to adequately predict disease development and outcome. One hallmark of cancer is telomere maintenance. For telomere maintenance, PCa cells exclusively employ telomera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40dfd83ec00f8bbc2ecfb8312fe3de5c
https://pubmed.ncbi.nlm.nih.gov/35267575
https://pubmed.ncbi.nlm.nih.gov/35267575