Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Georgia M Alexander"'
Autor:
Georgia M Alexander, Logan Y Brown, Shannon Farris, Daniel Lustberg, Caroline Pantazis, Bernd Gloss, Nicholas W Plummer, Patricia Jensen, Serena M Dudek
Publikováno v:
eLife, Vol 7 (2018)
Hippocampal oscillations arise from coordinated activity among distinct populations of neurons and are associated with cognitive functions. Much progress has been made toward identifying the contribution of specific neuronal populations in hippocampa
Externí odkaz:
https://doaj.org/article/b77e48b0097f416dbe2b54b4719ff264
Autor:
Natale R. Sciolino, Nicholas W. Plummer, Yu-Wei Chen, Georgia M. Alexander, Sabrina D. Robertson, Serena M. Dudek, Zoe A. McElligott, Patricia Jensen
Publikováno v:
Cell Reports, Vol 15, Iss 11, Pp 2563-2573 (2016)
Chemogenetic technologies, including the mutated human Gq-coupled M3 muscarinic receptor (hM3Dq), have greatly facilitated our ability to directly link changes in cellular activity to altered physiology and behavior. Here, we extend the hM3Dq toolkit
Externí odkaz:
https://doaj.org/article/382371775c1747b69ca902a58db2cb89
Autor:
Georgia M. Alexander, Shannon Farris, Jason R. Pirone, Chenguang Zheng, Laura L. Colgin, Serena M. Dudek
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Recent work has implicated hippocampal subfield CA2 in encoding social and contextual memory yet the neural mechanisms are not known. Here, Alexander and colleagues demonstrate that, compared to CA1 neurons, CA2 neurons modify their place fields when
Externí odkaz:
https://doaj.org/article/0bc09f47e5c84251aaeccfdc7b5a8a19
Publikováno v:
The European Journal of Neuroscience
Current methods of experimentally degrading the specialized extracellular matrix (ECM), perineuronal nets (PNNs) have several limitations. Genetic knockout of ECM components typically has only partial effects on PNNs, and knockout of the major ECM co
Autor:
Emma K Shaughnessy, Katharine E. McCann, Kelly E. Carstens, Georgia M. Alexander, Daniel Lustberg, Serena M. Dudek
Publikováno v:
J Clin Invest
Perineuronal nets (PNNs), a specialized form of extracellular matrix, are abnormal in the brains of people with Rett syndrome (RTT). We previously reported that PNNs function to restrict synaptic plasticity in hippocampal area CA2, which is unusually
Publikováno v:
eNeuro
A key goal in hippocampal research is to understand how neuronal activity is generated and organized across hippocampal subregions to enable memory formation and retrieval. Neuronal activity in CA2 is regulated by spatial and social investigation as
Autor:
Shannon Farris, Meilan Zhao, Georgia M. Alexander, Daniel Lustberg, Daniel Radzicki, Katharine E. McCann, Serena M. Dudek, Emma K Shaughnessy, Kelly E. Carstens
Publikováno v:
Molecular Psychiatry
Mineralocorticoid receptors (MRs) in the brain play a role in learning and memory, neuronal differentiation, and regulation of the stress response. Within the hippocampus, the highest expression of MRs is in area CA2. CA2 pyramidal neurons have a dis
Autor:
Jerrel L. Yakel, Serena M. Dudek, Patricia Jensen, Zhenglin Gu, Georgia M. Alexander, Inês Guerreiro, Boris Gutkin, Kathleen G. Smith
Publikováno v:
Cell Rep
Cell Reports
Cell Reports, Elsevier Inc, 2020, 31 (10), pp.107740. ⟨10.1016/j.celrep.2020.107740⟩
Cell Reports
Cell Reports, Elsevier Inc, 2020, 31 (10), pp.107740. ⟨10.1016/j.celrep.2020.107740⟩
Summary Muscarinic acetylcholine receptors (mAChRs) are critically involved in hippocampal theta generation, but much less is known about the role of nicotinic AChRs (nAChRs). Here we provide evidence that α7 nAChRs expressed on interneurons, partic
Autor:
Logan Y. Brown, Nicholas W. Plummer, Serena M. Dudek, Daniel Lustberg, Bernd Gloss, Georgia M. Alexander, Caroline B. Pantazis, Shannon Farris, Patricia Jensen
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Hippocampal oscillations arise from coordinated activity among distinct populations of neurons and are associated with cognitive functions. Much progress has been made toward identifying the contribution of specific neuronal populations in hippocampa
Autor:
Patricia Jensen, Logan Y. Brown, Shannon Farris, Serena M. Dudek, Bernd Gloss, Georgia M. Alexander, Nicholas W. Plummer, Caroline B. Pantazis, Daniel Lustberg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05f7883d6be34b38108a7b8ea1b0091f
https://doi.org/10.7554/elife.38052.033
https://doi.org/10.7554/elife.38052.033