Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Georgia M, Beasley"'
Autor:
Dirk Schadendorf, Gino K In, Mark R Middleton, Mohammed Milhem, Adel Samson, Bartosz Chmielowski, Michael K Wong, Robert S Coffin, Trisha M Wise-Draper, Eva Muñoz-Couselo, Joseph J Sacco, Georgia M Beasley, Judith Michels, Praveen K Bommareddy, Katy K Tsai, Jeannie W Hou, Alina Monteagudo, Tawnya Lynn Bowles, Ari M VanderWalde, Jason Alan Chesney, Fade Mahmoud, Walter Hong, Aaron Clack
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/4ff8ea73c0584af5a6764e1f92cc3eda
Autor:
Hong Zheng, Uzma Khan, Xiaofei Wang, Xiaoqing Yu, Georgia M Beasley, James Ronald, Jhanelle E Gray, Scott J Antonia, Steven Wolf, Neal E Ready, Bruna Pellini, Andreas N Saltos, Christy Arrowood, Ghassan El-Haddad, Tawee Tanvetyanon, Luiziane Guerra-Guevara, Lin Gu, Dana Foresman, Mark J Cantwell, Amer A Beg
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/105d880a19504b1fae2902e604088ef5
Autor:
Austin M. Eckhoff, Michael C. Brown, Karenia Landa, Ibtehaj Naqvi, Eda K. Holl, David Boczkowski, Ashley Fletcher, Kristen E. Rhodin, Minh Huy Giang, Bruce Sullenger, Georgia M. Beasley, Peter J. Allen, Smita K. Nair
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundMonocytes and monocyte-derived tumor infiltrating cells have been implicated in the immunosuppression and immune evasion associated with pancreatic adenocarcinoma (PDAC). Yet, precisely how monocytes in the periphery and tumor microenvironm
Externí odkaz:
https://doaj.org/article/1eb497b660224ba3b823ad6d334a8bd8
Autor:
Daniel Landi, Annick Desjardins, Matthias Gromeier, Darell D Bigner, Smita K Nair, Michael C Brown, Georgia M Beasley, David M Ashley, Yuanfan Yang, Zachary P McKay, Dina M Randazzo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
Background Antitumor mechanisms of CD4+ T cells remain crudely defined, and means to effectively harness CD4+ T-cell help for cancer immunotherapy are lacking. Pre-existing memory CD4+ T cells hold potential to be leveraged for this purpose. Moreover
Externí odkaz:
https://doaj.org/article/73dcacec3cd343d394456d6088d99ca1
Autor:
Kristen E. Rhodin, Denisse Porras Fimbres, Danielle N. Burner, Shayna Hollander, Margaret H. O’Connor, Georgia M. Beasley
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The presence of lymph node metastases is a well-studied prognostic factor for cutaneous melanoma. Characterization of melanoma lymph node metastases and their association with survival in multiple, large observational studies has led to recognition o
Externí odkaz:
https://doaj.org/article/01f1818af0a84a8fbe989ea01c5b5d32
Autor:
Matthias Gromeier, Darell D Bigner, Smita K Nair, David Boczkowski, Michael C Brown, Karenia Landa, Sin-Ho Jung, Georgia M Beasley, Norma E Farrow, Maria Angelica Selim, Rami N Al-Rohil, Aaron D Therien, Junheng Gao, Eda K Holl
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background We previously reported results from a phase 1 study testing intratumoral recombinant poliovirus, lerapolturev, in 12 melanoma patients. All 12 patients received anti-PD-1 systemic therapy before lerapolturev, and 11 of these 12 patients al
Externí odkaz:
https://doaj.org/article/04605eb95ab14089a2829c1d83ca4646
Autor:
Aaron D. Therien, Georgia M. Beasley, Kristen E. Rhodin, Norma E. Farrow, Douglas S. Tyler, David Boczkowski, Rami N. Al-Rohil, Eda K. Holl, Smita K. Nair
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionB cells are key regulators of immune responses in melanoma. We aimed to explore differences in the histologic location and activation status of B cell follicles in sentinel lymph nodes (SLN) of melanoma patients.MethodsFlow cytometry was
Externí odkaz:
https://doaj.org/article/b9f0f4ada7424c5ebc1dcb3d7d1046ae
Autor:
Michael C. Brown, Mubeen M. Mosaheb, Malte Mohme, Zachary P. McKay, Eda K. Holl, Jonathan P. Kastan, Yuanfan Yang, Georgia M. Beasley, E. Shelley Hwang, David M. Ashley, Darell D. Bigner, Smita K. Nair, Matthias Gromeier
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Innate intratumoral immunity might be important in enhancing oncolytic tumor immunotherapy. Here, the authors show that recombinant poliovirus signalling through TBK-IRF3 enhances tumor-infiltrating T cell activity and multi-cytokine function.
Externí odkaz:
https://doaj.org/article/60906122327e4f2e9beced154e87cbb7
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 3 (2022)
This review describes the current body of literature and ongoing clinical trials examining neoadjuvant immune checkpoint inhibitors (ICI) for patients with resectable stage III and IV melanoma. Based on prior success in treating metastatic melanoma a
Externí odkaz:
https://doaj.org/article/7ba199ce871d4a5782eb22dc5b228cce
Publikováno v:
Oncology and Therapy, Vol 8, Iss 2, Pp 261-275 (2020)
Abstract Introduction Since 2011, encouraging clinical trial results have led to approval of multiple new therapies for advanced melanoma, but the impact of these therapies outside of trial populations is largely unknown. This study examines use of n
Externí odkaz:
https://doaj.org/article/0bd8cac7d82049b5a9bfcef95fc39e34