Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Georgia L VonLehmden"'
Autor:
Cory M, Dungan, Vandre C, Figueiredo, Yuan, Wen, Georgia L, VonLehmden, Christopher J, Zdunek, Nicholas T, Thomas, C Brooks, Mobley, Kevin A, Murach, Camille R, Brightwell, Douglas E, Long, Christopher S, Fry, Philip A, Kern, John J, McCarthy, Charlotte A, Peterson
Publikováno v:
GeroScience. 44:1925-1940
With aging, skeletal muscle plasticity is attenuated in response to exercise. Here, we report that senescent cells, identified using senescence-associated β-galactosidase (SA β-Gal) activity and p21 immunohistochemistry, are very infrequent in rest
Autor:
Cory M Dungan, Camille R Brightwell, Yuan Wen, Christopher J Zdunek, Christine M Latham, Nicholas T Thomas, Alyaa M Zagzoog, Benjamin D Brightwell, Georgia L VonLehmden, Alexander R Keeble, Stanley J Watowich, Kevin A Murach, Christopher S Fry
Publikováno v:
Function (Oxford, England). 3(4)
Murine exercise models can provide information on factors that influence muscle adaptability with aging, but few translatable solutions exist. Progressive weighted wheel running (PoWeR) is a simple, voluntary, low-cost, high-volume endurance/resistan
Autor:
Cory M. Dungan, Kevin A. Murach, Christopher J. Zdunek, Zuo Jian Tang, Georgia L. VonLehmden, Camille R. Brightwell, Zachary Hettinger, Davis A. Englund, Zheng Liu, Christopher S. Fry, Antonio Filareto, Michael Franti, Charlotte A. Peterson
Publikováno v:
Aging Cell
Systemic deletion of senescent cells leads to robust improvements in cognitive, cardiovascular, and whole‐body metabolism, but their role in tissue reparative processes is incompletely understood. We hypothesized that senolytic drugs would enhance