Výsledky vyhledávání - "Georgia Culley"

957 Assessment of the spatial distribution and cell-to-cell interactions into the tumor micro-environment, within and between serial slides stained with Brightplex®, a sequential chromogenic multiplex assay

Autor: Aurelie Collignon, Alboukadel Kassambara, Alex Trinh, Maité Chamourin, Georgia Culley, Marion Olive, Clemence Jaume, Assil Benchaaben, Jerome Galon, Jacques Fieschi

Publikováno v: Regular and Young Investigator Award Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd866936e18cce13ba0a3358ee620da8
https://doi.org/10.1136/jitc-2022-sitc2022.0957

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Abstract 4624: Deciphering the tumor microenvironment at single-cell resolution using a workflow combining RNA transcript and protein detection with Brightplex®, a sequential chromogenic multiplex assay

Autor: Alex Trinh, Marion Olive, Aurélie Collignon, Maité Chamourin, Georgia Culley, Clemence Jaume, Vanina Leca, Assil Benchaaben, Giovanni Bussotti, Alboukadel Kassambara, Jerome Galon, Jacques Fieschi

Publikováno v: Cancer Research. 83:4624-4624

Tumor-infiltrating immune cells play an important role against cancer and are critical to control tumor growth and spread. Immunotherapy and immune checkpoint blockade, which aim to reinvigorate exhausted T cells have revolutionized cancer therapy. D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c33028ec47e5b977252cd321bcacbc23
https://doi.org/10.1158/1538-7445.am2023-4624

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Tonically active NMDA receptors - a signalling mechanism critical for interneuronal excitability in the CA1 stratum radiatum

Autor: Ilse Riebe, Georgia Culley, Victoria Fröjd, Eric Hanse, Shayma Radi, Karin Strand, Zita Dósa, Henrik Seth

Publikováno v: European Journal of Neuroscience. 43:169-178

In contrast to tonic extrasynaptic γ-aminobutyric acid (GABA)A receptor-mediated signalling, the physiological significance of tonic extrasynaptic N-methyl-D-aspartate (NMDA) receptor (NMDAR)-mediated signalling remains uncertain. In this study, rev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab33705f52d07bdf6fac5b703b7b1dbb
https://doi.org/10.1111/ejn.13128

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Human Cerebrospinal Fluid Promotes Neuronal Viability and Activity of Hippocampal Neuronal Circuits In Vitro

Autor: Marta, Perez-Alcazar, Georgia, Culley, Tim, Lyckenvik, Kristoffer, Mobarrez, Andreas, Bjorefeldt, Pontus, Wasling, Henrik, Seth, Frederik, Asztely, Andrea, Harrer, Bernhard, Iglseder, Ludwig, Aigner, Eric, Hanse, Sebastian, Illes

Publikováno v: Frontiers in Cellular Neuroscience

For decades it has been hypothesized that molecules within the cerebrospinal fluid (CSF) diffuse into the brain parenchyma and influence the function of neurons. However, the functional consequences of CSF on neuronal circuits are largely unexplored

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c70b175acc783601ea1b17dae0ee30ea

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The novel antidepressant ketamine enhances dentate gyrus proliferation with no effects on synaptic plasticity or hippocampal function in depressive‐like rats

Autor: Eric Hanse, Johan Svensson, Hans-Georg Kuhn, Nicklas Bergström, Johan Ehn, Anders Engström, Lars Karlsson, Parthenia Savvidi, Georgia Culley, Henrik Seth, Mats Andersson, Henrik Michaëlsson

Publikováno v: Acta Physiologica. 225:e13211

Aim Major depressive disorder is a common and debilitating condition with substantial economic impact. Treatment options, although effective, are aimed at relieving the symptoms with limited disease modification. Ketamine, a commonly used anaesthetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192a2dbeef915e705c7523ec0e8cfec5
https://doi.org/10.1111/apha.13211

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