Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Georgia Arentz"'
Autor:
Mitchell Acland, Parul Mittal, Georgia Arentz, Fergus Whitehead, Peter Hoffmann, Manuela Klingler-Hoffmann, Martin K. Oehler
Publikováno v:
Methods and Protocols, Vol 5, Iss 4, p 57 (2022)
The molecular analysis of small or rare patient tissue samples is challenging and often limited by available technologies and resources, such as reliable antibodies against a protein of interest. Although targeted approaches provide some insight, her
Externí odkaz:
https://doaj.org/article/679e2b6fdedc4bcdba832f3e9d2ba2b0
Autor:
Mitchell Acland, Georgia Arentz, Max Mussared, Fergus Whitehead, Peter Hoffmann, Manuela Klingler-Hoffmann, Martin K. Oehler
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Serous endometrial cancer (SEC) and high grade serous ovarian cancer (HGSOC) are aggressive gynecological malignancies with high rates of metastasis and poor prognosis. Endometrial intraepithelial carcinoma (EIC), the precursor for SEC, and serous tu
Externí odkaz:
https://doaj.org/article/08ff05f4f0c1401fbea2e78c98ae29ab
Autor:
Georgia Arentz, Parul Mittal, Manuela Klingler-Hoffmann, Mark R. Condina, Carmela Ricciardelli, Noor A. Lokman, Gurjeet Kaur, Martin K. Oehler, Peter Hoffmann
Publikováno v:
Cancers; Volume 15; Issue 7; Pages: 2172
Refereed/Peer-reviewed Eighty percent of ovarian cancer patients initially respond to chemotherapy, but the majority eventually experience a relapse and die from the disease with acquired chemoresistance. In addition, 20% of patients do not respond t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdea3e8e3b52714e4e08e706c5feed4f
Autor:
Georgia Arentz, Mitchell Acland, Martin K. Oehler, Peter Hoffmann, Fergus Whitehead, Manuela Klingler-Hoffmann, Max Mussared
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology, Vol 10 (2020)
Serous endometrial cancer (SEC) and high grade serous ovarian cancer (HGSOC) are aggressive gynecological malignancies with high rates of metastasis and poor prognosis. Endometrial intraepithelial carcinoma (EIC), the precursor for SEC, and serous tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad919fdff8702fd10570f92b55662f8
https://doi.org/10.3389/fonc.2020.523989
https://doi.org/10.3389/fonc.2020.523989
Autor:
Scott R. Clark, Georgia Arentz, Tracy Air, Bernhard T. Baune, Peter Hoffmann, David Stacey, K Oliver Schubert
Publikováno v:
Journal of Proteomics. 188:63-70
In order to accelerate the understanding of pathophysiological mechanisms and clinical biomarker discovery and in psychiatry, approaches that integrate multiple -omics platforms are needed. We introduce a workflow that investigates a narrowly defined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1379a3f7a4716d9485a5947c6a420e59
https://doi.org/10.1016/j.jprot.2018.02.023
https://doi.org/10.1016/j.jprot.2018.02.023
Autor:
Colin J.R. Stewart, Georgia Arentz, Lyron J. Winderbaum, Gurjeet Kaur, Martin K. Oehler, Jonathan Carter, Manuela Klingler-Hoffmann, Peter Hoffmann, Yee Leung, Parul Mittal, Lyndal Anderson, James Scurry
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1865:846-857
The prediction of lymph node metastasis using clinic-pathological data and molecular information from endometrial cancers lacks accuracy and is therefore currently not routinely used in patient management. Consequently, although only a small percenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27fdd712895641829d4cb93193554d7e
https://doi.org/10.1016/j.bbapap.2016.10.010
https://doi.org/10.1016/j.bbapap.2016.10.010
Autor:
Arun V. Everest-Dass, Martin K. Oehler, Mark R. Condina, Gurjeet Kaur, Manuela Klingler-Hoffmann, Matthew T. Briggs, Georgia Arentz, Nicolle H. Packer, Peter Hoffmann
Protein glycosylation, particularly N‐linked glycosylation, is a complex post‐translational modification (PTM), which plays an important role in protein folding and conformation, regulating protein stability and activity, cell‐cell interaction,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e065466ff6fee1d797ccdf65741a6d15
https://hdl.handle.net/11541.2/134918
https://hdl.handle.net/11541.2/134918
Autor:
Sarah E. Kidd, Bryan R. Coad, Andrew C Marshall, John B. Bruning, Peter Hoffmann, Georgia Arentz, Stephanie J. Lamont-Friedrich
Aspergillus fumigatus infections are associated with high mortality rates and high treatment costs. Limited available antifungals and increasing antifungal resistance highlight an urgent need for new antifungals. Thioredoxin reductase (TrxR) is essen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edbf14cabb31fc5c2f7dbbadb31b5018
https://hdl.handle.net/11541.2/136261
https://hdl.handle.net/11541.2/136261
Autor:
Peter Hoffmann, Lyron J. Winderbaum, Georgia Arentz, Manuela Klingler-Hoffmann, Gurjeet Kaur, Parul Mittal, Lyndal Anderson, Chao Zhang, Noor A. Lokman, Jonathan Carter, Colin J.R. Stewart, Martin K. Oehler, Yee Leung, James Scurry
Publikováno v:
PROTEOMICS. 16:1793-1801
Metastasis is a crucial step of malignant progression and is the primary cause of death from endometrial cancer. However, clinicians presently face the challenge that conventional surgical-pathological variables, such as tumour size, depth of myometr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81b724154bac53161149ab731f6b4f4
https://doi.org/10.1002/pmic.201500455
https://doi.org/10.1002/pmic.201500455
Autor:
Peter Hoffmann, Martin K. Oehler, Gurjeet Kaur, Manuela Klingler-Hoffmann, Georgia Arentz, Chao Zhang, Parul Mittal
Publikováno v:
PROTEOMICS - Clinical Applications. 10:217-229
This review discusses the current status of proteomics technology in endometrial cancer diagnosis, treatment and prognosis. The first part of this review focuses on recently identified biomarkers for endometrial cancer, their importance in clinical u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70df102395ac9adb9e644f80abc5660c
https://doi.org/10.1002/prca.201500055
https://doi.org/10.1002/prca.201500055