Výsledky vyhledávání - "Georgi Trifonov"

The reovirus μ2 C-terminal loop inversely regulates NTPase and transcription functions versus binding to factory-forming μNS and promotes replication in tumorigenic cells

Autor: Mark Kubanski, Nashae Narayan, Francisca Cristi, Maya Shmulevitz, Wan Kong Wynton Yip, Georgi Trifonov

Publikováno v: J Virol

The wild-type reovirus serotype 3 Dearing PL strain (T3wt) is being heavily evaluated as an oncolytic and immunotherapeutic treatment for cancers. Mutations that promote reovirus entry into tumor cells were previously reported to enhance oncolysis; h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225d233be2c412667b941eed2ee9d358
https://pubmed.ncbi.nlm.nih.gov/33658345

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