Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Georgeta Bocheva"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5122 (2024)
While primarily produced in the pineal gland, melatonin’s influence goes beyond its well-known role in regulating sleep, nighttime metabolism, and circadian rhythms, in the field of chronobiology. A plethora of new data demonstrates melatonin to be
Externí odkaz:
https://doaj.org/article/4303ba4d84c84850bac270d23d6e5adc
Autor:
Georgeta Bocheva, Lina Malinova, Dimitar Bakalov, Georgi Bogdanov, Julieta Hristova, Dobrin Svinarov
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 36, Iss 1, Pp 631-636 (2022)
AbstractThe skin manifestations in hypothyroidism are common but their advanced forms do not have adequate therapy. Along with achievement of euthyroidism, thyroid-associated dermatopathy (TAD) needs an inhibition of the proliferation and activation
Externí odkaz:
https://doaj.org/article/2902eb2c173540c1a7ab5fa86e9ac542
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10502 (2023)
The increase in air pollution worldwide represents an environmental risk factor that has global implications for the health of humans worldwide. The skin of billions of people is exposed to a mixture of harmful air pollutants, which can affect its ph
Externí odkaz:
https://doaj.org/article/3ba16a7942c54f6c82342925cb1a8292
Publikováno v:
Veterinary Sciences, Vol 10, Iss 2, p 122 (2023)
Thyroid hormones play an important role in the modeling of neural networks in the brain. Besides its metabolic effects, thyroid dysfunction, and hypothyroidism in particular, is frequently associated with cognitive decline and depressive-like behavio
Externí odkaz:
https://doaj.org/article/34998467afec4351b848fe09ef977331
Autor:
Georgeta Bocheva, Radomir M. Slominski, Zorica Janjetovic, Tae-Kang Kim, Markus Böhm, Kerstin Steinbrink, Russel J. Reiter, Konrad Kleszczyński, Andrzej T. Slominski
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1238 (2022)
The skin, being the largest organ in the human body, is exposed to the environment and suffers from both intrinsic and extrinsic aging factors. The skin aging process is characterized by several clinical features such as wrinkling, loss of elasticity
Externí odkaz:
https://doaj.org/article/3dec0c7c5c8243178a9f1345ef2ecb15
Publikováno v:
Redox Report, Vol 23, Iss 1, Pp 180-187 (2018)
Objectives: We investigated the mutual effects of overt hypothyroidism and prolonged sunlight exposure on free radical accumulation and oxidative skin damage. Methods: Free radical accumulation was evaluated by monitoring the transformation of 3-(4,5
Externí odkaz:
https://doaj.org/article/ad38f4eef8a84748871d31ffa24904ec
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 9097 (2021)
The active metabolites of vitamin D3 (D3) and lumisterol (L3) exert a variety of antiaging and photoprotective effects on the skin. These are achieved through immunomodulation and include anti-inflammatory actions, regulation of keratinocytes prolife
Externí odkaz:
https://doaj.org/article/3cacd89f304149d29e5c30aa839169f5
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2798 (2019)
Skin aging is accompanied by a gradual loss of function, physiological integrity and the ability to cope with internal and external stressors. This is secondary to a combination of complex biological processes influenced by constitutive and environme
Externí odkaz:
https://doaj.org/article/5ad97b1ac65e470ba7d5a06948a11c06
Publikováno v:
Journal of Medical Biochemistry
Journal of Medical Biochemistry, Vol 40, Iss 1, Pp 10-16 (2021)
Journal of Medical Biochemistry, Vol 40, Iss 1, Pp 10-16 (2021)
Reactive oxygen species (ROS) are produced in the body during normal metabolism by means of enzymes and non-enzymatic chemical reduction of molecular oxygen. In case of the prevalence of ROS formation over their elimination, highly reactive free radi
Autor:
Anna A. Brożyna, Mohammad Athar, Tae Kang Kim, Zorica Janjetovic, Andrzej Slominski, Robert C. Tuckey, Georgeta Bocheva, Allen S.W. Oak
Publikováno v:
Anticancer Res
Background/aim The hormonally-active form of vitamin D, 1,25(OH)2D3, demonstrated activity against oral squamous cell carcinoma (OSCC). Cytochrome P450scc (CYP11A1)-derived vitamin D hydroxyderivatives, such as 20(OH)D3 and 1,20(OH)2D3, have overlapp