Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Georges Riss"'
Autor:
Karin Wertz, Christopher Lankin, Samir Acharya, Georges Riss, Brad Greatrix, Nicole Seifert, Petra Buchwald-Hunziker, Regina Goralczyk, Ulrich Hoeller, Emmanuelle Kuntz, Willi Hunziker
Publikováno v:
Archives of Biochemistry and Biophysics. 455:48-60
High dose beta-carotene supplementation of smokers was associated with increased lung cancer risk in two intervention trials. It was proposed that generation of apocarotenals in smoke-exposed lungs impaired retinoic acid (RA) signaling, leading to sq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f8f4053ae82446efb7adda4a6b72c3
https://doi.org/10.1016/j.abb.2006.08.023
https://doi.org/10.1016/j.abb.2006.08.023
Autor:
Regina Goralczyk, Karin Wertz, Heinrich Bachmann, Petra Buchwald Hunziker, Claude-Pierre Aebischer, Brad Greatrix, Barbara Lenz, Georges Riss
Publikováno v:
Nutrition and Cancer. 54:252-262
Dietary modulation of cancer & cancer biomarkers; Dietary modulation of carcinogenesis-related pathways. Dietary item or component studied: beta-carotene Outcome studied: lung adenoma; gene regulation of the putative tumor suppressor RARbeta in mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ceda358138ff89a077945be0a711ac
https://doi.org/10.1207/s15327914nc5402_12
https://doi.org/10.1207/s15327914nc5402_12
Autor:
Karin Wertz, Willi Hunziker, Petra Buchwald Hunziker, Nicole Seifert, Georges Riss, Adrian Wyss, Regina Goralczyk
Publikováno v:
Pure and Applied Chemistry. 78:1539-1550
UVA exposure causes skin photoaging by singlet oxygen (1O2)-mediated induction of matrix metalloproteases (MMPs). We assessed whether β-carotene, a carotenoid known as 1O2 quencher and retinoic acid (RA) precursor, interferes with UVA-induced gene r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a65b26d8e119de3229e56608d1265a02
https://doi.org/10.1351/pac200678081539
https://doi.org/10.1351/pac200678081539
Autor:
Aleksander B. Skotnicki, Marek Bodzioch, Karin Wertz, Thomas Langmann, Magdalena Zawada, Zofia Lach, Edyta Zdziƚowska, Christopher Moele, Anna Polus, Marta Libura, Jadwiga Hartwich, Tomasz Sacha, Marta Szostek, Georges Riss, Gerd Schmitz, Aldona Dembińska-Kieć, Regina Goralczyk
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1740:206-214
The influence of β-carotene (BC) and its derivatives on differentiation, proliferation and apoptosis in three human acute leukemia cell lines was studied. We investigated: (i) the cellular uptake of BC, (ii) the cytotoxicity, (iii) the effect on cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e7066781cc07fae716d474674dabbb
https://doi.org/10.1016/j.bbadis.2004.12.005
https://doi.org/10.1016/j.bbadis.2004.12.005
Autor:
Claude-P. Aebischer, Georges Riss, Karin Wertz, Brad Geatrix, Barbara Lenz, Petra Buchwald Hunziker, Regina Goralczyk, Heinrich Bachmann
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1740(2):179-188
We studied the influence of beta-carotene on the tobacco smoke carcinogen 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumor development in the A/J-mouse model. The normally low beta-carotene absorption was facilitated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adca7097863bbd391003c75f4a2e7b9e
Autor:
Christopher Lankin, Karin Wertz, Petra Buchwald Hunziker, Nicole Seifert, Adrian Wyss, Regina Goralczyk, Georges Riss
Publikováno v:
Free Radical Biology and Medicine. 37:654-670
UVA exposure causes skin photoaging by singlet oxygen (1)O(2)-mediated induction of, e.g., matrix metalloproteases (MMPs). We assessed whether pretreatment with beta-carotene, a (1)O(2) quencher and retinoic acid (RA) precursor, interferes with UVA-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a81da34784d440b687b6099bf1f276a
https://doi.org/10.1016/j.freeradbiomed.2004.05.018
https://doi.org/10.1016/j.freeradbiomed.2004.05.018
Autor:
Adrian WYSS, Gabriele M. WIRTZ, Wolf-D. WOGGON, Roland BRUGGER, Markus WYSS, Arno FRIEDLEIN, Georges RISS, Heinrich BACHMANN, Willi HUNZIKER
Publikováno v:
Biochemical Journal. 354:521-529
β,β-Carotene 15,15′-dioxygenase cleaves β,β-carotene into two molecules of retinal, and is the key enzyme in the metabolism of β,β-carotene to vitamin A. The enzyme has been known for more than 40 years, yet all attempts to purify the protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::739f39efea71342527e6a5887427a71e
https://doi.org/10.1042/bj3540521
https://doi.org/10.1042/bj3540521
Rapid determination of 25-hydroxy vitamin D3 in swine tissue using an isotope dilution HPLC-MS assay
Autor:
Alexandra Schattner, Ulrich Höller, Arturo Piñón Quintana, Katharina Olszewski, Georges Riss, Richard Gössl, Carlos Simões Nunes
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 878(13-14)
A rapid method for quantification of 25-hydroxy vitamin D3 in different swine tissues based on isotope dilution HPLC-MS has been developed and validated. Six times deuterated analyte is used as internal standard. The method is fast and can be perform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf6dd6721f3d76bc1bf4821d990d810
https://pubmed.ncbi.nlm.nih.gov/20299291
https://pubmed.ncbi.nlm.nih.gov/20299291
Autor:
Anika E. Wagner, Hubert Hug, Gerald Rimbach, Volker Elste, Richard Gössl, Georges Riss, Bernd Mussler, Luca Barella
Publikováno v:
Annals of nutritionmetabolism. 53(2)
Ascorbigen (ABG) is a natural compound that represents a breakdown product of the glucosinolates that are present in Brassica vegetables. It is postulated that ABG may have anticarcinogenic activity; however, the underlying molecular and cellular mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be7fbbe091f060e9f8148c26130aa16
https://pubmed.ncbi.nlm.nih.gov/18997460
https://pubmed.ncbi.nlm.nih.gov/18997460
Autor:
Regina Goralczyk, Mark Berneburg, Jean Krutmann, Susanne Wild, Viola Kürten, Georges Riss, Jörg Eicker
Publikováno v:
Photochemicalphotobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 2(6)
Mutations of mitochondrial DNA accumulate during normal aging and can be detected at elevated levels in skin prematurely aged by chronic exposure to ultraviolet (UV) light (photoaging). In normal human fibroblasts, we have previously demonstrated tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce210b74f1a2124da441c119d9bd9cf2
https://pubmed.ncbi.nlm.nih.gov/12859149
https://pubmed.ncbi.nlm.nih.gov/12859149