Výsledky vyhledávání - "Georges Rawadi"

Akademický článek

Selection of a novel strain of Christensenella minuta as a future biotherapy for Crohn’s disease

Autor: Karima Relizani, Katy Le Corf, Camille Kropp, Rebeca Martin-Rosique, Déborah Kissi, Guillaume Déjean, Lisa Bruno, Ccori Martinez, Georges Rawadi, Frédéric Elustondo, Wilfrid Mazier, Sandrine P. Claus

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)

Abstract Microbiome-based therapies for inflammatory bowel diseases offer a novel and promising therapeutic approach. The human commensal bacteria of the species Christensenella minuta (C. minuta) have been reported consistently missing in patients a

Externí odkaz: https://doaj.org/article/7924a0febbf4419998171066a6578be0

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Akademický článek

The Keystone commensal bacterium Christensenella minuta DSM 22607 displays anti-inflammatory properties both in vitro and in vivo

Autor: Camille Kropp, Katy Le Corf, Karima Relizani, Kevin Tambosco, Ccori Martinez, Florian Chain, Georges Rawadi, Philippe Langella, Sandrine P. Claus, Rebeca Martin

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

Abstract Christensenellaceae is a family of subdominant commensal bacteria found in humans. It is thought to play an important role in gut health by maintaining microbial symbiosis. Indeed, these bacteria occur at significantly lower levels or are ab

Externí odkaz: https://doaj.org/article/9f0a79730e0d456f87c210b29cb9337f

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Akademický článek

Entering First-in-Human Clinical Study With a Single-Strain Live Biotherapeutic Product: Input and Feedback Gained From the EMA and the FDA

Autor: Jeanne-Céleste Paquet, Sandrine P. Claus, Magali Cordaillat-Simmons, Wilfrid Mazier, Georges Rawadi, Laure Rinaldi, Frédéric Elustondo, Alice Rouanet

Publikováno v: Frontiers in Medicine, Vol 8 (2021)

During the last decade, a plethora of novel therapies containing live microorganisms as active substance(s) has emerged with the aim to treat, prevent, or cure diseases in human beings. Both the Food and Drug Administration (FDA) and the European Dir

Externí odkaz: https://doaj.org/article/12fe8187f03b467aa6f1a45b97d56a1a

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Akademický článek

Identifying a Novel Bile Salt Hydrolase from the Keystone Gut Bacterium Christensenella minuta

Autor: Guillaume Déjean, Héloïse Tudela, Lisa Bruno, Déborah Kissi, Georges Rawadi, Sandrine P. Claus

Publikováno v: Microorganisms, Vol 9, Iss 6, p 1252 (2021)

Christensenella minuta are human gut dwelling bacteria that have been proposed as key members of the gut microbiome, regulating energy balance and adiposity of their host. We formerly identified that a novel strain of C. minuta (strain DSM33407) boos

Externí odkaz: https://doaj.org/article/5df6802f8aa14a5b8ac090a709c09a36

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Akademický článek

A New Strain of Christensenella minuta as a Potential Biotherapy for Obesity and Associated Metabolic Diseases

Autor: Wilfrid Mazier, Katy Le Corf, Ccori Martinez, Héloïse Tudela, Déborah Kissi, Camille Kropp, Chrislain Coubard, Marion Soto, Frédéric Elustondo, Georges Rawadi, Sandrine P. Claus

Publikováno v: Cells, Vol 10, Iss 4, p 823 (2021)

Obesity is associated with gut microbiota dysbiosis, characterized by a high Firmicutes/Bacteroidetes ratio. Gut-dwelling bacteria of the Christensenellaceae family have been proposed to act as keystones of the human gut ecosystem and to prevent adip

Externí odkaz: https://doaj.org/article/49d113ac22db489e817fc04cebdc3f1c

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The Keystone commensal bacterium Christensenella minuta DSM 22607 displays anti-inflammatory properties both in vitro and in vivo

Autor: Philippe Langella, Katy Le Corf, Kevin Tambosco, Rebeca Martín, Ccori Martinez, Florian Chain, Camille Kropp, Sandrine P. Claus, Karima Relizani, Georges Rawadi

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports

Christensenellaceae is a family of subdominant commensal bacteria found in humans. It is thought to play an important role in gut health by maintaining microbial symbiosis. Indeed, these bacteria occur at significantly lower levels or are absent in i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b133f7f5b2808a5f6f46fbf82b57ea
https://doaj.org/article/9f0a79730e0d456f87c210b29cb9337f

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