Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Georges R Mohn"'
Autor:
Ton van de Kuil, Barbara Hoebee, Antoon Opperhuizen, Harro Hokse, Jan van Benthem, Joyce M. de Stoppelaar, Henny W. Verharen, Georges R. Mohn
Publikováno v:
Mutagenesis. 15:155-164
A successful in vivo application of the cytokinesis blocked micronucleus assay for the detection of aneuploidy induced by carbendazim (CARB) was carried out in the granuloma pouch assay. This was performed in two ways: (i) in vivo exposure of the ski
Autor:
Joyce M. de Stoppelaar, Mirjam Bedaf, Jan van Benthem, Wout Slob, Barbara Hoebee, Georges R. Mohn, Henny W. Verharen, Ton van de Kuil
Publikováno v:
Mutagenesis. 14:621-632
The purpose of the present study was to determine the effect of a single oral dose of carbendazim (CARB) on the frequencies of numerical chromosome aberrations in sperm and on micronuclei in peripheral blood erythrocytes of rats. Dual colour FISH on
Autor:
Georges R. Mohn, Jacob G. Jansen, A Degroot, Paul H.M. Lohman, C Vanteijlingen, Harry Vrieling, A Vanzeeland
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 307:95-105
Base substitutions and frameshifts induced by genotoxic agents are considered to result mainly from incomplete repair and incorrect replication of modified nucleotides in DNA. In this study, induction and persistence of O 6 -alkyl- and 7-alkylguanine
Autor:
B. Hoebee, J.M. de Stoppelaar, R.F. Suijkerbuijk, Georges R. Mohn, H.J. van Kranen, P. Faessen
Publikováno v:
Cytogenetic and Genome Research. 67:23-26
The rat N-rαs protooncogene has been assigned to chromosome 2q34 by fluorescence in situ hybridization on rat metaphase chromosomes. This was accomplished using two recently isolated genomic clones with a length of 8.2 and 4.1 kb.
Publikováno v:
Mutation Research Letters. 281:93-98
Publikováno v:
Mutation Research Letters. 263:137-142
In the present studies EDTA-permeabilised E. coli cells were used in the DNA repair HMA to investigate the organ-specific effects of aflatoxin B 1
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 247:87-96
In the present study the sensitivity of differential lethality as an endpoint for monitoring the presence of organ-specific genotoxic factors within the DNA-repair host-mediated assay (HMA) was determined. The induction of differential lethality in c
Autor:
Georges R. Mohn, A.A. van Zeeland, Paul H.M. Lohman, Jacob G. Jansen, Ad D. Tates, Harry Vrieling
Publikováno v:
Clinical Chemistry. 41:1841-1843
We exposed experimental animals to a series of alkylating agents that induced mutations at the X-linked hprt gene of T lymphocytes. We then isolated the mutant cells and analyzed the molecular nature of the mutations by amplification of hprt cDNA seq
Autor:
Fekadu Kassie, Maria Uhl, Evelyne F. Lhoste, Sonja Ecker, Asima Chakraborty, Siegfried Knasmüller, Georges R. Mohn
Publikováno v:
Archives of Toxicology
Archives of Toxicology, Springer Verlag, 2003, 77 (8), pp.477-484. ⟨10.1007/s00204-003-0469-4⟩
Archives of Toxicology, Springer Verlag, 2003, 77 (8), pp.477-484. ⟨10.1007/s00204-003-0469-4⟩
International audience; The aim of the present study was to investigate the antimutagenic effects of chrysin (CR), a flavonoid compound contained in many fruits, vegetables and honey. Earlier investigations with bacterial indicators showed that CR is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400e72cf08cde9a677fa268d46a30d07
https://hal.inrae.fr/hal-02683093
https://hal.inrae.fr/hal-02683093
Autor:
Patrick P. J. Mulder, Jos C. Olde Boerrigter, Arne van der Gen, Georges R. Mohn, Johan Lugtenburg, Jan Cornelisse
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 108:79-80
Aceanthrene (2) and aceanthrylene (1) are easily prepared in high yield from aceanthrenequinone (3) by means of a double Wolff-Kishner reduction.