Cooperative cell–cell actin network remodeling to perform Gap junction endocytosis

Autor: Dominique Segretain, Mathilde Di Marco, Chloé Dufeu, Diane Carette, Alain Trubuil, Georges Pointis

Publikováno v: Basic and Clinical Andrology, Vol 33, Iss 1, Pp 1-11 (2023)

Abstract Background The endocytosis of Gap junction plaques (GJP) requires cytoskeletal forces to internalize such large membranous structures. Actin, which partners the connexin proteins constituting Gap junctions and is located close to Annular Gap

Externí odkaz: https://doaj.org/article/04defef642ed49a393a291ddd916ad35

Effects of a mixture of low doses of atrazine and benzo[a]pyrene on the rat seminiferous epithelium either during or after the establishment of the blood-testis barrier in the rat seminiferous tubule culture model

Autor: Antonine Blondet, Marie-Hélène Perrard, Diane Carette, Guillaume Martin, Philippe Durand, Georges Pointis

Publikováno v: Toxicology in Vitro
Toxicology in Vitro, Elsevier, 2020, 62, pp.104699. ⟨10.1016/j.tiv.2019.104699⟩
Toxicology in Vitro, Elsevier, In press, 62, pp.104699. ⟨10.1016/j.tiv.2019.104699⟩
Toxicology in Vitro, 2020, 62, pp.104699. ⟨10.1016/j.tiv.2019.104699⟩

International audience; Atrazine (ATZ), a widely used agricultural pesticide and benzo[a]pyrene (BaP), a ubiquitous environmental human carcinogen can induce alterations of spermatogenesis. In the present study, we showed first that our seminiferous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60e93015c29c2b808499db1e84235fd
https://hal.archives-ouvertes.fr/hal-02870404

Physiological roles of connexins and pannexins in reproductive organs

Autor: Mark Kibschull, Dominique Segretain, Alexandra Gellhaus, Diane Carette, Georges Pointis, Jerome Gilleron

Publikováno v: Cellular and Molecular Life Sciences. 72:2879-2898

Reproductive organs are complex and well-structured tissues essential to perpetuate the species. In mammals, the male and female reproductive organs vary on their organization, morphology and function. Connectivity between cells in such tissues plays

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99bd9c951fe25626d6752dace98baa0a
https://doi.org/10.1007/s00018-015-1965-4

Multiple and complex influences of connexins and pannexins on cell death

Autor: Dominique Segretain, Diane Carette, Jerome Gilleron, Georges Pointis

Publikováno v: Biochimica et biophysica acta. Biomembranes. 1860(1)

Cell death is a fundamental process for organogenesis, immunity and cell renewal. During the last decades a broad range of molecular tools were identified as important players for several different cell death pathways (apoptosis, pyroptosis, necrosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d599663532bebfe7c3900baa69b19241
https://pubmed.ncbi.nlm.nih.gov/28625689

Ultrastructural localization and distribution of Nardilysin in mammalian male germ cells

Autor: Dominique Segretain, Georges Pointis, Diane Carette, M. Di Marco, Jean-Noël Bacro, Jerome Gilleron

Publikováno v: Basic and clinical andrology
Basic and clinical andrology, BioMed Central, 2016, 26 (5), ⟨10.1186/s12610-016-0032-9⟩
Basic and Clinical Andrology

Background NRD convertase, also termed Nardilysin, is a Zn++ metalloendopeptidase that specifically cleaves the N-terminus of arginine and lysine residues into dibasic moieties. Although this enzyme was found located within the testis, its function i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a15dff126b279a9c0fdfd8c75b1a57
https://hal.archives-ouvertes.fr/hal-01297923