Tetanus Toxin Synthesis is Under the Control of A Complex Network of Regulatory Genes in Clostridium tetani

Autor: Lucile Plourde, Vincent Colombié, Olivier Gorgette, Dominique Garnier, Cecile Deneve, Diana Chapeton-Montes, Christine Schmitt, Holger Brüggemann, Catherine Thouvenot, Fabien Barbirato, Sandy Demay, Michel R. Popoff, Georges Michel Haustant

Publikováno v: Chapeton-Montes, D, Plourde, L, Deneve, C, Garnier, D, Barbirato, F, Colombié, V, Demay, S, Haustant, G, Gorgette, O, Schmitt, C, Thouvenot, C, Brüggemann, H & Popoff, M R 2020, ' Tetanus Toxin Synthesis is Under the Control of A Complex Network of Regulatory Genes in Clostridium tetani ', Toxins, vol. 12, no. 5, 328 . https://doi.org/10.3390/toxins12050328
Toxins
Toxins, MDPI, 2020, 12 (5), pp.328. ⟨10.3390/toxins12050328⟩
Volume 12
Issue 5
Toxins, Vol 12, Iss 328, p 328 (2020)
Toxins, 2020, 12 (5), pp.328. ⟨10.3390/toxins12050328⟩

Clostridium tetani produces a potent neurotoxin, the tetanus toxin (TeNT), which is responsible for an often-fatal neurological disease (tetanus) characterized by spastic paralysis. Prevention is efficiently acquired by vaccination with the TeNT toxo

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https://pure.au.dk/portal/da/publications/tetanus-toxin-synthesis-is-under-the-control-of-a-complex-network-of-regulatory-genes-in-clostridium-tetani(3a664e86-641a-4ce2-931f-5f9635ef8ac9).html

The catalytic domains ofClostridium sordelliilethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid

Autor: Georges Michel Haustant, Serge Pauillac, D. Borden Lacy, Sylviane Hoos, Arnaud Blondel, Alexandre Chenal, Michel R. Popoff, Carolina Varela Chavez, Patrick England

Publikováno v: Cellular Microbiology. 17:1477-1493

Summary Clostridium sordellii lethal toxin (TcsL) is a potent virulence factor belonging to the large clostridial glucosylating toxin family. TcsL enters target cells via receptor-mediated endocytosis and delivers the N-terminal catalytic domain (Tcs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e80f018109f805bdf5e87e44cd04d20
https://doi.org/10.1111/cmi.12449

The catalytic domains of C lostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid

Autor: Carolina, Varela Chavez, Sylviane, Hoos, Georges Michel, Haustant, Alexandre, Chenal, Patrick, England, Arnaud, Blondel, Serge, Pauillac, D Borden, Lacy, Michel Robert, Popoff

Publikováno v: Cellular Microbiology
Cellular Microbiology, 2015, 17 (10), pp.1477-1493. ⟨10.1111/cmi.12449⟩
Cellular Microbiology, Wiley, 2015, 17 (10), pp.1477-1493. ⟨10.1111/cmi.12449⟩

International audience; Clostridium sordellii lethal toxin (TcsL) is a potent virulence factor belonging to the large clostridial glucosylating toxin family. TcsL enters target cells via receptor-mediated endocytosis and delivers the N-terminal catal

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https://hal-pasteur.archives-ouvertes.fr/pasteur-01400914

Listeria monocytogenes faecal carriage is common and depends on the gut microbiota

Autor: Lukas Hafner, Marc Garcia-Garcera, Christophe Burucoa, Marc Lecuit, Sophie H A Nusser, Maxime Pichon, Alexandra Moura

Publikováno v: Nature Communications
Nature Communications, 2021, 12 (1), pp.6826. ⟨10.1038/s41467-021-27069-y⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.6826. ⟨10.1038/s41467-021-27069-y⟩
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

Listeria genus comprises two pathogenic species, L. monocytogenes (Lm) and L. ivanovii, and non-pathogenic species. All can thrive as saprophytes, whereas only pathogenic species cause systemic infections. Identifying Listeria species’ respective b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1547a6d6912b415ef2af7446c75418
https://hal-pasteur.archives-ouvertes.fr/pasteur-03457267