Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Georges M, Gharabawi"'
Autor:
Jasmanda H. Wu, Ibrahim Turkoz, Georges M. Gharabawi, Mary J. Kujawa, Ramy Mahmoud, Dennis A. Revicki, Leah Kleinman, Gahan J. Pandina
Publikováno v:
Journal of Affective Disorders. 118:139-146
Background The Patient-Rated Troubling Symptoms of Depression (PaRTS-D) instrument assesses the presence and troublesomeness of 8 commonly reported depression-related symptoms from the patient's perspective. A post hoc analysis of a double-blind, ran
Autor:
Margaret A. Kirshner, Robert R. Bies, Denise Sorisio, Marci L. Chew, Mark E. Lehman, Georges M. Gharabawi, Benoit H. Mulsant, Ramy A. Mahmoud, Andrew Greenspan, Bruce G. Pollock
Publikováno v:
Journal of the American Geriatrics Society. 56:1333-1341
The objective of this study was to measure the anticholinergic activity (AA) of medications commonly used by older adults. A radioreceptor assay was used to investigate the AA of 107 medications. Six clinically relevant concentrations were assessed f
Autor:
Andrew Greenspan, George S. Alexopoulos, Charles F. Reynolds, Cynthia A. Bossie, Ibrahim Turkoz, Carla M. Canuso, Georges M. Gharabawi
Publikováno v:
The American Journal of Geriatric Psychiatry. 16:21-30
The effect of risperidone augmentation of citalopram for relapse prevention in older patients with antidepressant-resistant depression was evaluated.Patients with major depression agedor =55 years who had failed at least one adequate trial of an anti
Autor:
George M. Simpson, Ramy A. Mahmoud, Ibrahim Turkoz, Cynthia A. Bossie, Mary J. Kujawa, Georges M. Gharabawi
Publikováno v:
Journal of Nervous & Mental Disease. 195:976-982
This post hoc analysis explored the role of insight as a mediator of functioning in a 52-week, double-blind, international trial of 323 patients with schizophrenia or schizoaffective disorder receiving risperidone long-acting injectable. Measures inc
Autor:
Philip D. Harvey, Robert M. Bilder, Richard S.E. Keefe, Georges M. Gharabawi, Michael G. Aman, Gahan Pandina
Publikováno v:
Biological Psychiatry. 62:226-234
Effects of risperidone on cognitive function in children with disruptive behavior disorders (DBDs) and subaverage intelligence quotient (IQ) were assessed.Data from two 6-week, double-blind, placebo-controlled studies (n = 228) were combined, as were
Autor:
Bruce G. Pollock, Georges M. Gharabawi, Margaret A. Kirshner, Mark E. Lehman, Benoit H. Mulsant, Shitij Kapur, Marci L. Chew, Andrew Greenspan, Robert R. Bies
Publikováno v:
Schizophrenia Research. 88:63-72
Background Atypical antipsychotics clozapine, olanzapine, and quetiapine have significant affinity for the muscarinic receptors in vitro, while aripiprazole, risperidone, and ziprasidone do not. Dissimilarity in binding profiles may contribute to the
Autor:
Cynthia A. Bossie, Steven G. Potkin, Marcia F.T. Rupnow, Michael H. Davidson, J K Trivedi, Colette Kosik-Gonzalez, Young Zhu, Ramy A. Mahmoud, Georges M. Gharabawi, Andrew Greenspan, Victoria Burtea
Publikováno v:
Schizophrenia Research. 85:254-265
This study compared the effects of atypical antipsychotics (risperidone or quetiapine) with placebo and with each other in recently exacerbated patients with schizophrenia requiring hospitalization.This international, randomized, double-blind study i
Autor:
Georges M. Gharabawi, Ramy A. Mahmoud, Cynthia A. Bossie, Fiona Dunbar, Carla M. Canuso, Philippe Bouhours, Amy Loescher, Ibrahim Turkoz, Robert A. Lasser, Mark Hyman Rapaport, Charles B. Nemeroff, Martin B. Keller
Publikováno v:
Neuropsychopharmacology. 31:2505-2513
Approximately one-third of persons with depression do not respond to antidepressant monotherapy. Studies suggest that atypical antipsychotic augmentation may benefit these patients. We investigated the longer-term efficacy of risperidone augmentation
Publikováno v:
Schizophrenia Research. 77:129-139
Treatment-emergent tardive dyskinesia (TD) can be a serious side effect of antipsychotic treatment. Atypical antipsychotics are associated with a lower risk for TD than are conventional agents. A long-acting atypical antipsychotic, with more stable b
Publikováno v:
The International Journal of Neuropsychopharmacology. 8:427-438
Modern atypical antipsychotics have advantages over older neuroleptics. We hypothesize that their utility may be further enhanced by sustained drug delivery without daily oral self-dosing. This report examines the effects of a year of treatment with