Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Georges Khoury"'
High level of genomic divergence in orf-I p12 and hbz genes of HTLV-1 subtype-C in Central Australia
Autor:
Ashley Hirons, David Yurick, Natasha Jansz, Paula Ellenberg, Genoveffa Franchini, Lloyd Einsiedel, Georges Khoury, Damian F. J. Purcell
Publikováno v:
Retrovirology, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Human T cell lymphotropic virus type 1 (HTLV-1) infection remains a largely neglected public health problem, particularly in resource-poor areas with high burden of communicable and non-communicable diseases, such as some remote p
Externí odkaz:
https://doaj.org/article/c6ea34dcb4d948959ac09adc24989d88
Autor:
Georges Khoury, Jeremy K Ward, Julien Mancini, Amandine Gagneux-Brunon, Liem Binh Luong Nguyen
Publikováno v:
JMIR Public Health and Surveillance, Vol 10, p e45837 (2024)
BackgroundHealth literacy involves individuals’ knowledge, personal skills, and confidence to take action to evaluate and appraise health-related information and improve their health or that of their community. ObjectiveThis study aimed to analyze
Externí odkaz:
https://doaj.org/article/e2ab5a0210c040eeaa90eed1cfb87deb
Autor:
Michelle Y-H Lee, Georges Khoury, Moshe Olshansky, Secondo Sonza, Glen P. Carter, James McMahon, Timothy P. Stinear, Stephen J. Turner, Sharon R. Lewin, Damian F. J. Purcell
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Latent HIV-1 provirus in infected individuals on suppressive therapy does not always remain transcriptionally silent. Both HIV-1 LTR and human gene promoter derived transcriptional events can contribute HIV-1 sequences to the mRNA produced in the cel
Externí odkaz:
https://doaj.org/article/c2f040ad12cf4dec9245f544d8ddf3bf
Publikováno v:
Clinical Case Reports, Vol 8, Iss 12, Pp 2664-2672 (2020)
Abstract In an immediate implant placement and provisionalization strategy, the esthetic results of multiple adjacent implants can be obtained even with compromised periodontium by implementing the “one‐by‐one” protocol. Staged extractions of
Externí odkaz:
https://doaj.org/article/78329c9b49e74d618c6fa9e1e0646d97
Autor:
Maria Omsland, Micol Silic-Benussi, Ramona Moles, Sarkis Sarkis, Damian F. J. Purcell, David Yurick, Georges Khoury, Donna M. D’Agostino, Vincenzo Ciminale, Genoveffa Franchini
Publikováno v:
Retrovirology, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Human T cell leukemia virus type-1 (HTLV-1) was the first retrovirus found to cause cancer in humans, but the mechanisms that drive the development of leukemia and other diseases associated with HTLV-1 infection remain to be fully understood
Externí odkaz:
https://doaj.org/article/8f341af7b670479fbb958b0eed69e1ae
Autor:
Sarkis Sarkis, Veronica Galli, Ramona Moles, David Yurick, Georges Khoury, Damian F. J. Purcell, Genoveffa Franchini, Cynthia A. Pise-Masison
Publikováno v:
Retrovirology, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract The human T cell leukemia virus type 1 (HTVL-1), first reported in 1980 by Robert Gallo’s group, is the etiologic agent of both cancer and inflammatory diseases. Despite approximately 40 years of investigation, the prognosis for afflicted
Externí odkaz:
https://doaj.org/article/1a26ed6d6b764de89805abf12f4b8935
Autor:
Ramona Moles, Sarkis Sarkis, Veronica Galli, Maria Omsland, Damian F. J. Purcell, David Yurick, Georges Khoury, Cynthia A. Pise-Masison, Genoveffa Franchini
Publikováno v:
Retrovirology, Vol 16, Iss 1, Pp 1-15 (2019)
Abstract The extraordinarily high prevalence of HTLV-1 subtype C (HTLV-1C) in some isolated indigenous communities in Oceania and the severity of the health conditions associated with the virus impress the great need for basic and translational resea
Externí odkaz:
https://doaj.org/article/411c1b95cd5e47279b95b5c27aca8261
Autor:
Matthew S. Parsons, Anne B. Kristensen, Kevin J. Selva, Wen Shi Lee, Thakshila Amarasena, Robyn Esterbauer, Adam K. Wheatley, Benjamin R. Bavinton, Anthony D. Kelleher, Andrew E. Grulich, Georges Khoury, Jennifer A. Juno, Stephen J. Kent
Publikováno v:
EBioMedicine, Vol 70, Iss , Pp 103518- (2021)
Background: HIV-1 infections occur following viral exposure at anogenital mucosal surfaces in the presence of semen. Semen contains immunosuppressive and pro-inflammatory factors. Semen from HIV-1-infected donors contains anti-HIV-1 antibodies. We as
Externí odkaz:
https://doaj.org/article/dd1e6f70ef79467f9bca32d7896dcc2d
Autor:
Georges Khoury, Michelle Y. Lee, Sri H. Ramarathinam, James McMahon, Anthony W. Purcell, Secondo Sonza, Sharon R. Lewin, Damian F. J. Purcell
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
HIV-1 Tat protein is essential for virus production. RNA-binding proteins that facilitate Tat production may be absent or downregulated in resting CD4+ T-cells, the main reservoir of latent HIV in people with HIV (PWH) on antiretroviral therapy (ART)
Externí odkaz:
https://doaj.org/article/7c0b9c153da347e2a64fc1579b1b9317
Autor:
Jennifer M. Zerbato, Georges Khoury, Wei Zhao, Matthew J. Gartner, Rachel D. Pascoe, Ajantha Rhodes, Ashanti Dantanarayana, Megan Gooey, Jenny Anderson, Peter Bacchetti, Steven G. Deeks, James McMahon, Michael Roche, Thomas A. Rasmussen, Damian FJ Purcell, Sharon R. Lewin
Publikováno v:
EBioMedicine, Vol 65, Iss , Pp 103241- (2021)
Background: One strategy being pursued to clear latently infected cells that persist in people living with HIV (PLWH) on antiretroviral therapy (ART) is to activate latent HIV infection with a latency reversing agent (LRA). Surrogate markers that acc
Externí odkaz:
https://doaj.org/article/d906ec4beead49649c5521b1bb6e22dd