Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Georges E R, Grau"'
Autor:
Kartika Wardhani, Aviva Levina, Biyun Sun, Haipei Zou, Georges E. R. Grau, F. Richard Keene, J. Grant Collins, Peter A. Lay
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 664 (2024)
Selective staining of extracellular vesicles (EVs) is a major challenge for diagnostic and therapeutic applications. Herein, the EV labeling properties of a new class of tetranuclear polypyridylruthenium(II) complexes, Rubb7-TNL and Rubb7-TL, as phos
Externí odkaz:
https://doaj.org/article/40a8d0f6a6834389b75a9b72abc5d2bc
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-13 (2018)
Abstract Background Cerebral malaria (CM) is a fatal complication of Plasmodium infection, mostly affecting children under the age of five in the sub-Saharan African region. CM pathogenesis remains incompletely understood, although sequestered infect
Externí odkaz:
https://doaj.org/article/21961ceda0f9443499e1c784603963e4
Autor:
Frederic Sierro, Georges E. R. Grau
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Complications from malaria parasite infections still cost the lives of close to half a million people every year. The most severe is cerebral malaria (CM). Employing murine models of CM, autopsy results, in vitro experiments, neuroimaging and microsc
Externí odkaz:
https://doaj.org/article/a7b2c0152e874508afd3a1d1177baa5b
Autor:
Kartika Wardhani, Aviva Levina, Biyun Sun, Georges E. R. Grau, F. Richard Keene, J. Grant Collins, Peter A. Lay
Publikováno v:
Chemical Communications.
A tetranuclear Ru dye for selective staining of extracellular vesicles for studies of in vitro blood–brain barrier permeability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79cad6c027bca842394b23a110b95876
https://doi.org/10.1039/d2cc05827h
https://doi.org/10.1039/d2cc05827h
Autor:
Sophie Lev, Keren Kaufman-Francis, Desmarini Desmarini, Pierre G. Juillard, Cecilia Li, Sebastian A. Stifter, Carl G. Feng, Tania C. Sorrell, Georges E. R. Grau, Yong-Sun Bahn, Julianne T. Djordjevic
Publikováno v:
mSphere, Vol 2, Iss 1 (2017)
ABSTRACT Phosphate acquisition by fungi is regulated by the phosphate-sensing and acquisition (PHO) signaling pathway. Cryptococcus neoformans disseminates from the lung to the brain and is the commonest cause of fungal meningitis worldwide. To inves
Externí odkaz:
https://doaj.org/article/e6ebd73772e44c50ab5233ebc0ecbd4b
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181674 (2017)
To investigate the role of the protein C system, endothelial protein C receptor (EPCR) and thrombomodulin (TM) in the pathogenesis of malaria-associated acute respiratory distress syndrome (ARDS) in relation to hemozoin and proinflammatory cytokines-
Externí odkaz:
https://doaj.org/article/b0d7b3470a8e4c6faf3be6f01ece4b28
Autor:
Sarah E. Hochman, Theresa F. Madaline, Samuel C. Wassmer, Emmie Mbale, Namjong Choi, Karl B. Seydel, Richard O. Whitten, Julie Varughese, Georges E. R. Grau, Steve Kamiza, Malcolm E. Molyneux, Terrie E. Taylor, Sunhee Lee, Danny A. Milner, Kami Kim
Publikováno v:
mBio, Vol 7, Iss 1 (2016)
Externí odkaz:
https://doaj.org/article/960f3a82cfed43c3b7f630eaf05343cb
Autor:
Sarah E. Hochman, Theresa F. Madaline, Samuel C. Wassmer, Emmie Mbale, Namjong Choi, Karl B. Seydel, Richard O. Whitten, Julie Varughese, Georges E. R. Grau, Steve Kamiza, Malcolm E. Molyneux, Terrie E. Taylor, Sunhee Lee, Danny A. Milner, Kami Kim
Publikováno v:
mBio, Vol 6, Iss 5 (2015)
ABSTRACT Cerebral malaria (CM) is a major contributor to malaria deaths, but its pathophysiology is not well understood. While sequestration of parasitized erythrocytes is thought to be critical, the roles of inflammation and coagulation are controve
Externí odkaz:
https://doaj.org/article/5189f1d3b89541a3baa1c8eae4df4826
Autor:
Saparna Pai, Jim Qin, Lois Cavanagh, Andrew Mitchell, Fatima El-Assaad, Rohit Jain, Valery Combes, Nicholas H Hunt, Georges E R Grau, Wolfgang Weninger
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004236 (2014)
During experimental cerebral malaria (ECM) mice develop a lethal neuropathological syndrome associated with microcirculatory dysfunction and intravascular leukocyte sequestration. The precise spatio-temporal context in which the intravascular immune
Externí odkaz:
https://doaj.org/article/4440c7935f8b4968b212bdb451ffca8b
Publikováno v:
PLoS Pathogens, Vol 10, Iss 3, p e1003839 (2014)
In patients with cerebral malaria (CM), higher levels of cell-specific microparticles (MP) correlate with the presence of neurological symptoms. MP are submicron plasma membrane-derived vesicles that express antigens of their cell of origin and phosp
Externí odkaz:
https://doaj.org/article/217911ce5d1b497b81dfdc6300dbbdc3