Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Georges Bellon"'
Autor:
Thibaut Galissier, Christophe Schneider, Saviz Nasri, Lukshe Kanagaratnam, Caroline Fichel, Christelle Coquelet, Marie-Danièle Diebold, Reza Kianmanesh, Georges Bellon, Stéphane Dedieu, Aude Marchal Bressenot, Camille Boulagnon-Rombi
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154326 (2016)
Medical research projects become increasingly dependent on biobanked tissue of high quality because the reliability of gene expression is affected by the quality of extracted RNA. Hence, the present study aimed to determine if clinical, surgical, his
Externí odkaz:
https://doaj.org/article/2d3bf1393f97491bbc9a52e619f7e8c4
Autor:
Anne-Pascaline Martin, Janos Sapi, Isabelle Villena, Sylvie Brassart-Pasco, Kristina Brazhnik, Igor Nabiev, Gautier Moroy, Alyona Sukhanova, Georges Bellon, Erika Bourguet
Publikováno v:
Bioconjugate Chemistry
Bioconjugate Chemistry, American Chemical Society, 2016, 27 (4), pp.1067-1081. ⟨10.1021/acs.bioconjchem.6b00065⟩
Bioconjugate Chemistry, American Chemical Society, 2016, 27 (4), pp.1067-1081. ⟨10.1021/acs.bioconjchem.6b00065⟩
International audience; The development of chemically designed matrix metalloprotease (MMP) inhibitors has advanced the understanding of the roles of MMPs in different diseases. Most MMP probes designed are fluorogenic substrates, often suffering fro
Autor:
Camille, Boulagnon-Rombi, Christophe, Schneider, Chloé, Leandri, Albin, Jeanne, Virginie, Grybek, Aude Marchal, Bressenot, Coralie, Barbe, Benjamin, Marquet, Saviz, Nasri, Christelle, Coquelet, Caroline, Fichel, Nicole, Bouland, Arnaud, Bonnomet, Reza, Kianmanesh, Anne-Sophie, Lebre, Olivier, Bouché, Marie-Danièle, Diebold, Georges, Bellon, Stéphane, Dedieu
Publikováno v:
Oncotarget
LRP1 (low-density lipoprotein receptor-related protein 1), a multifunctional endocytic receptor, has recently been identified as a hub within a biomarker network for multi-cancer clinical outcome prediction. As its role in colon cancer has not yet be
Autor:
Georges Bellon, François-Xavier Maquart, Marie-Aude Robert de Rancher, Jean-Baptiste Oudart, Nathalie Schneider
Publikováno v:
Clinical Chemistry. 64:614-615
A 78-year-old woman treated with dabigatran for atrial fibrillation was admitted for acute renal failure. Coagulation investigations showed an overdose of dabigatran, requiring injection of the antidote, idarucizumab. Fig. 1 shows urine immunofixatio
Autor:
François-Xavier Maquart, Laurent Ramont, Jean Claude Monboisse, Georges Bellon, E. Luczka, Sylvie Brassart-Pasco, Aurélie Dupont-Deshorgue, Jean-Baptiste Oudart, Hans-Peter Bächinger, Sergei P. Boudko
Publikováno v:
Analytical Biochemistry. 437:111-117
Type XIX collagen is a minor collagen associated with basement membranes in vascular, neuronal, mesenchymal, and epithelial tissues. We demonstrated that the NC1, C-terminal, domain of collagen XIX inhibits the migration capacities of tumor cells and
Autor:
Georges Bellon, Caroline Fichel, Christelle Coquelet, Marie-Danièle Diebold, Lukshe Kanagaratnam, Aude Bressenot, Saviz Nasri, Christophe Schneider, Reza Kianmanesh, Thibaut Galissier, Camille Boulagnon-Rombi, Stéphane Dedieu
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154326 (2016)
PLoS ONE
PLoS ONE
Medical research projects become increasingly dependent on biobanked tissue of high quality because the reliability of gene expression is affected by the quality of extracted RNA. Hence, the present study aimed to determine if clinical, surgical, his
Autor:
Alain J.P. Alix, Erika Bourguet, William Hornebeck, Georges Bellon, Janos Sapi, Martine Decarme, Franck Augé, Dominique Guillaume, Matthieu Rouffet, Jean-Yves Laronze, Gautier Moroy, Gwennaël LeDour, Haquima ElMourabit
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2008, 16 (18), pp.8745-8759
Bioorganic and Medicinal Chemistry, Elsevier, 2008, 16 (18), pp.8745-8759
Hydrazide derivatives of Ilomastat, carrying either aryl groups or distinct alkyl and arylsulfonyl moieties were synthesized and evaluated for their MMP inhibitory activity. Potent and selective MMP-9 inhibition (IC(50)=3 nM) was observed for compoun
Autor:
Jean-Hugues Renault, Gauthier Moroy, Alix Toribio, Catherine Mirand, Haquima El Mourabit, Alexandra Dassonville, Clément Denhez, Georges Bellon, Janos Sapi, Alain J.P. Alix, Erika Bourguet, Martine Decarme, William Hornebeck
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:4753-4766
Structural analogues of Ilomastat (Galardin), containing unsaturation(s) and chain extension carrying bulky phenyl group or alkyl moieties at P'1 were synthesized and purified by centrifugal partition chromatography. They were analyzed for their inhi
Autor:
Arnaud Robinet, William Hornebeck, Stéphane Poitevin, Jean-Hubert Cauchard, Georges Bellon, Jean-Claude Mazière, Hélène Bobichon
Publikováno v:
Biochemical and Biophysical Research Communications. 345:681-687
UVA irradiation, dose-dependently (5-20 J/cm{sup 2}), was shown to impair the morphogenic differentiation of human microvascular endothelial cells (HMECs) on Matrigel. Parallely, UVA down-regulated the expression of MMP-2 and MT1-MMP, both at the pro
Publikováno v:
Pathologie Biologie. 53:405-410
Gelatinase A, a member of the matrix metalloproteinase family, contains three fibronectin type II (FnII)-like modules that are inserted within its catalytic domain. These FnII modules, defined as exosites, play an essential role in targeting the enzy