Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Georges Baffet"'
Autor:
Sophie Rose, Frédéric Ezan, Marie Cuvellier, Arnaud Bruyère, Vincent Legagneux, Sophie Langouët, Georges Baffet
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Generating the proliferation of differentiated normal adult human hepatocytes is a major challenge and an expected central step in understanding the microenvironmental conditions that regulate the phenotype of human hepatocytes in vitro. In
Externí odkaz:
https://doaj.org/article/5698f8c84c2c4af488edf5e3538a8768
Autor:
Michaël Ruff, Anthony Leyme, Fabienne Le Cann, Dominique Bonnier, Jacques Le Seyec, Franck Chesnel, Laurent Fattet, Ruth Rimokh, Georges Baffet, Nathalie Théret
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139179 (2015)
The increased expression of the Disintegrin and Metalloprotease ADAM12 has been associated with human cancers, however its role remain unclear. We have previously reported that ADAM12 expression is induced by the transforming growth factor, TGF-β an
Externí odkaz:
https://doaj.org/article/32d2e83f62bd4946a600658760f68a72
Publikováno v:
International Journal of Hepatology, Vol 2012 (2012)
Primary cultures of hepatocytes are powerful models in studying the sequence of events that are necessary for cell progression from a G0-like state to S phase. The models mimic the physiological process of hepatic regeneration after liver injury or p
Externí odkaz:
https://doaj.org/article/e77fd99b08dc4145b999b94812107268
Autor:
Marie Cuvellier, Sophie Rose, Frédéric Ezan, Ulrich Jarry, Hugo de Oliveira, Arnaud Bruyère, Christophe Drieu La Rochelle, Vincent Legagneux, Sophie Langouët, Georges Baffet
Publikováno v:
Biofabrication
Biofabrication, 2022, 14 (3), pp.035021. ⟨10.1088/1758-5090/ac7825⟩
Biofabrication, 2022, 14 (3), pp.035021. ⟨10.1088/1758-5090/ac7825⟩
In recent decades, 3D in vitro cultures of primary human hepatocytes (PHHs) have been increasingly developed to establish models capable of faithfully mimicking main liver functions. The use of 3D bioprinting, capable of recreating structures compose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24696cb58c3e4a1bfd25c326486c066
https://univ-rennes.hal.science/hal-03710469/document
https://univ-rennes.hal.science/hal-03710469/document
Autor:
Fabrice Nesslany, Sophie Langouët, Georges Baffet, Vincent Legagneux, Marie Cuvellier, Jennifer Carteret, Arnaud Bruyère, Frédéric Ezan, Sophie Rose
Publikováno v:
Archives of Toxicology
Archives of Toxicology, Springer Verlag, 2021, ⟨10.1007/s00204-021-03178-x⟩
Archives of Toxicology, 2022, 96 (1), pp.243-258. ⟨10.1007/s00204-021-03178-x⟩
Archives of Toxicology, Springer Verlag, 2021, ⟨10.1007/s00204-021-03178-x⟩
Archives of Toxicology, 2022, 96 (1), pp.243-258. ⟨10.1007/s00204-021-03178-x⟩
International audience; The liver is essential in the elimination of environmental and food contaminants. Given the interspecies differences between rodents and humans, the development of relevant in vitro human models is crucial to investigate liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d59f9e3fad2b3b2f84dc4dcc783722d
https://hal.archives-ouvertes.fr/hal-03439397
https://hal.archives-ouvertes.fr/hal-03439397
Autor:
Sophie Rose, Jean-Christophe Fricain, Georges Baffet, Sophie Langouët, Frédéric Ezan, Marie Cuvellier, Hugo Oliveira, Vincent Legagneux
Publikováno v:
Biomaterials
Biomaterials, Elsevier, 2020, 269, pp.120611. ⟨10.1016/j.biomaterials.2020.120611⟩
Biomaterials, 2021, 269, pp.120611. ⟨10.1016/j.biomaterials.2020.120611⟩
Biomaterials, Elsevier, 2021, 269, pp.120611. ⟨10.1016/j.biomaterials.2020.120611⟩
Biomaterials, Elsevier, 2020, 269, pp.120611. ⟨10.1016/j.biomaterials.2020.120611⟩
Biomaterials, 2021, 269, pp.120611. ⟨10.1016/j.biomaterials.2020.120611⟩
Biomaterials, Elsevier, 2021, 269, pp.120611. ⟨10.1016/j.biomaterials.2020.120611⟩
International audience; Bioprinting is an emergent technology that has already demonstrated the capacity to create complex and/or vascularized multicellular structures with defined and organized architectures, in a reproducible and high throughput wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b96b6644b91f09f612ee7a5f525688
https://pubmed.ncbi.nlm.nih.gov/33385685
https://pubmed.ncbi.nlm.nih.gov/33385685
Autor:
Medjda Bellamri, Laurent Vernhet, Georges Baffet, Robert J. Turesky, Sophie Langouët, Ludovic Le Hégarat
Publikováno v:
Environmental and Molecular Mutagenesis. 57:656-667
Heterocyclic aromatic amines (HAA) are formed in cooked meat, poultry and fish but also arise in tobacco smoke and exhaust gases. HAA are potential human carcinogens, which require metabolic activation to exert their genotoxicity. Human tissues can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::485d458e620f01f425814df67a7fb340
https://doi.org/10.1002/em.22059
https://doi.org/10.1002/em.22059
Publikováno v:
Drug Metabolism and Pharmacokinetics
Drug Metabolism and Pharmacokinetics, 2018, 33 (1), pp.S60. ⟨10.1016/j.dmpk.2017.11.203⟩
Drug Metabolism and Pharmacokinetics, Japanese Society for the Study of Xenobiotics, 2018, 33 (1), pp.S60. ⟨10.1016/j.dmpk.2017.11.203⟩
Drug Metabolism and Pharmacokinetics, 2018, 33 (1), pp.S60. ⟨10.1016/j.dmpk.2017.11.203⟩
Drug Metabolism and Pharmacokinetics, Japanese Society for the Study of Xenobiotics, 2018, 33 (1), pp.S60. ⟨10.1016/j.dmpk.2017.11.203⟩
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef8e0cdf30e700a2bc8b52039239277
https://univ-rennes.hal.science/hal-01795274
https://univ-rennes.hal.science/hal-01795274
Publikováno v:
Matrix Biology
Matrix Biology, Elsevier, 2018, 68-69, pp.122-149. ⟨10.1016/j.matbio.2018.02.004⟩
Matrix Biology, 2018, 68-69, pp.122-149. ⟨10.1016/j.matbio.2018.02.004⟩
Matrix Biology, 2018, 〈10.1016/j.matbio.2018.02.004〉
Matrix Biology, Elsevier, 2018, 68-69, pp.122-149. ⟨10.1016/j.matbio.2018.02.004⟩
Matrix Biology, 2018, 68-69, pp.122-149. ⟨10.1016/j.matbio.2018.02.004⟩
Matrix Biology, 2018, 〈10.1016/j.matbio.2018.02.004〉
International audience; The collagen network is altered in fibrotic diseases associated with extracellular matrix (ECM) biosynthesis and remodeling. This mini-review focuses on the quantitative and qualitative modifications of collagens occurring at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb91dde8367d8e61892c90d5c8f7b270
https://pubmed.ncbi.nlm.nih.gov/29458139
https://pubmed.ncbi.nlm.nih.gov/29458139
Autor:
Frédéric Ezan, François Tiaho, Nathalie Théret, Jérémy Bomo, Medjda Bellamri, Sophie Langouët, Georges Baffet
Publikováno v:
Journal of Cellular Biochemistry. 117:708-720
Mechanical forces influence the growth and shape of virtually all tissues and organs. Recent studies show that increased cell contractibility, growth and differentiation might be normalized by modulating cell tensions. Particularly, the role of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20f1592ef147ca04adac620162f89c70
https://doi.org/10.1002/jcb.25356
https://doi.org/10.1002/jcb.25356