Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation

Autor: Conor L Mallucci, Michael D Jenkinson, Elizabeth J Conroy, John C Hartley, Michaela Brown, Joanne Dalton, Tom Kearns, Tracy Moitt, Michael J Griffiths, Giovanna Culeddu, Tom Solomon, Dyfrig Hughes, Carrol Gamble, Benedetta Pettorini, Christopher Parks, Ajay Sinha, Libby van Tonder, Mitchel T Foster, Catherine McMahon, Neil Buxton, Emmanuel Chavredakis, Andrew R Brodbelt, David DA Lawson, Paul R Eldridge, Jibril O Farah, Rasheed Zakaria, Sunderland Geraint, Guirish Solanki, Desiderio Rodrigues, Richard Edwards, Adam Williams, Matthew Garnett, Angelos Kolias, Peter JA Hutchinson, Karen Caldwell, Silvia Tarantino, Paul Leach, Malik Zaben, Gulam Zilani, Dmitri Shastin, Joseph Merola, Rahim Hussain, Ravindra Vemaraju, Liudmila Selezneva, Georgina Radford, Nadine Lloyd, Darach Crimmins, John Caird, Maria N Sayar, Noelle O'Mahoney, Dominic Thompson, Kristian Aquilina, Gregory James, Roger Strachan, Nitin Mukerji, Bassel Zebain, Bhaskar Thakur, Holly Dickson, Eniola Nsirim, Adedamola Adebayo, John Goodden, Kenan Deniz, Janet Clarke, Mary Kambafwile, Ian Anderson, Rebecca Chave-Cox, Asim Sheik, Ryan Mathew, Oliver Richards, Soumya Mukherjee, Paul Chumas, Atul Tyagi, Gnanamurthy Sikakumar, Admed Toma, Linda D'Antona, Laurence Watkins, Lewis Thorne, Claudia Craven, Vanessa Bassen, Damien Holliman, Ian Coulter, Donald Macarthur, Maria Cartmill, Simon Howarth, Stuart Smith, Shazia Javed, Ian Kamaly, Roberto Ramirez, Andrew King, Ardash Nadig, John Thorne, Shungu Ushewokunze, Saurabh Sinha, Hesham Zaki, John McMullan, Diederik Bulters, Ryan Waters, George Zilidis, Joy Roach, Ahmed Sadek, Patrick Holton, Ardalan Zolnourian, Aabir Chakraborty, Jothy Kandasamy, Mark Hughes, Paul M Brennan

Publikováno v: Lancet
LANCET

Summary Background Insertion of a ventriculoperitoneal shunt for hydrocephalus is one of the commonest neurosurgical procedures worldwide. Infection of the implanted shunt affects up to 15% of these patients, resulting in prolonged hospital treatment

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