Zobrazeno 1 - 10
of 83
pro vyhledávání: '"George Z. Retsch-Bogart"'
Autor:
Jessica E Pittman, Michelle S Skalland, Scott D Sagel, Bonnie W Ramsey, Nicole Mayer-Hamblett, George Z. Retsch-Bogart
Publikováno v:
Journal of Cystic Fibrosis. 21:946-949
Chronic azithromycin improves outcomes in cystic fibrosis (CF), but its mechanism of action is unclear. The OPTIMIZE trial demonstrated improvement in time to first pulmonary exacerbation in children with new Pseudomonas treated with azithromycin. Az
Autor:
Amalia S. Magaret, Mark Warden, Noah Simon, Sonya Heltshe, George Z. Retsch-Bogart, Bonnie W. Ramsey, Nicole Mayer-Hamblett
Publikováno v:
J Cyst Fibros
BACKGROUND: Given future challenges in conducting large randomized, placebo controlled trials for future CF therapeutics development, we evaluated the potential for using external historical controls to either enrich or replace traditional concurrent
Autor:
Jorge Lascano, George Z. Retsch-Bogart, James F Chmiel, Lisa Saiman, Joanne Billings, Sarah J. Morgan, Ada Kong, Arthur Baines, Jerry A. Nick, Nicole Mayer-Hamblett, Shannon Kirby, David P. Nichols, Pradeep K. Singh, Lindsay J. Caverly, Ronald L. Gibson, Sonya L. Heltshe, Hossein Sadeghi
Publikováno v:
Thorax. 77:581-588
RationaleInhaled tobramycin and oral azithromycin are common chronic therapies in people with cystic fibrosis and Pseudomonas aeruginosa airway infection. Some studies have shown that azithromycin can reduce the ability of tobramycin to kill P. aerug
Publikováno v:
Cytokines of the Lung ISBN: 9781003066927
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c74cee61f2bbc2b7f34d71a38af0209f
https://doi.org/10.1201/9781003066927-4
https://doi.org/10.1201/9781003066927-4
Autor:
Sanja Stanojevic, Stephanie D. Davis, Lucy Perrem, Felix Ratjen, Michelle Shaw, George Z. Retsch-Bogart
Publikováno v:
J Cyst Fibros
Introduction The Cystic Fibrosis Questionnaire-Revised (CFQ-R) Respiratory score is a validated and widely used patient-reported outcome. This study aimed to establish changes in the score with acute respiratory events in preschool children with CF a
Autor:
Sanja Stanojevic, Renee Jensen, George Z. Retsch-Bogart, Stephanie D. Davis, Felix Ratjen, Michelle Shaw, Martinus C. Oppelaar
Publikováno v:
Pediatric Pulmonology. 55:649-653
BACKGROUND The multiple breath washout (MBW) test may be most useful in tracking disease progression over time to inform treatment decisions. In the clinical setting, alternative outcomes, which can be obtained quickly and easily, may facilitate inte
Autor:
Amy Hoffman, Christopher H. Goss, Patricia Burks, David P. Nichols, John P. Clancy, George Z. Retsch-Bogart, Jill M. VanDalfsen, K. Pearson, Nicole Mayer-Hamblett, Daniel B. Rosenbluth
Publikováno v:
Journal of Cystic Fibrosis
Highlights • The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) global pandemic has significantly impacted CF clinical research. • An electronic survey was sent to Therapeutic Development Network (TDN) sites to monitor the impact. •
Autor:
John P. Clancy, K. De Boeck, Michael W. Konstan, Pavel Drevinek, George Z. Retsch-Bogart, Amalia Magaret, Isabelle Fajac, Bradley S. Quon, Anthony G. Durmowicz, S.M. Singleton, Donald R. VanDevanter, Jane C. Davies, Scott C. Bell, Scott H. Donaldson, Patrick A. Flume, K. Pearson, Jennifer L. Taylor-Cousar, Christopher H. Goss, Damian G Downey, S. van Koningsbruggen-Rietschel, Nicole Mayer-Hamblett, Felix Ratjen, Tim W.R. Lee, Jill M. VanDalfsen, Dave P. Nichols
Publikováno v:
J Cyst Fibros
Mayer-Hamblett, N, van Koningsbruggen-Rietschel, S, Nichols, D P, VanDevanter, D R, Davies, J C, Lee, T, Durmowicz, A G, Ratjen, F, Konstan, M W, Pearson, K, Bell, S C, Clancy, J P, Taylor-Cousar, J L, De Boeck, K, Donaldson, S H, Downey, D G, Flume, P A, Drevinek, P, Goss, C H, Fajac, I, Magaret, A S, Quon, B S, Singleton, S M, VanDalfsen, J M & Retsch-Bogart, G Z 2020, ' Building global development strategies for cf therapeutics during a transitional cftr modulator era ', Journal of Cystic Fibrosis, vol. 19, no. 5, pp. 677-687 . https://doi.org/10.1016/j.jcf.2020.05.011
Mayer-Hamblett, N, van Koningsbruggen-Rietschel, S, Nichols, D P, VanDevanter, D R, Davies, J C, Lee, T, Durmowicz, A G, Ratjen, F, Konstan, M W, Pearson, K, Bell, S C, Clancy, J P, Taylor-Cousar, J L, De Boeck, K, Donaldson, S H, Downey, D G, Flume, P A, Drevinek, P, Goss, C H, Fajac, I, Magaret, A S, Quon, B S, Singleton, S M, VanDalfsen, J M & Retsch-Bogart, G Z 2020, ' Building global development strategies for cf therapeutics during a transitional cftr modulator era ', Journal of Cystic Fibrosis, vol. 19, no. 5, pp. 677-687 . https://doi.org/10.1016/j.jcf.2020.05.011
As CFTR modulator therapy transforms the landscape of cystic fibrosis (CF) care, its lack of uniform access across the globe combined with the shift towards a new standard of care creates unique challenges for the development of future CF therapies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f025201b49f0b3ebc6ac06682476b6f3
https://europepmc.org/articles/PMC7492419/
https://europepmc.org/articles/PMC7492419/
Autor:
Jonathan H. Rayment, Stephanie D. Davis, George Z. Retsch-Bogart, Felix Ratjen, Sanja Stanojevic
Publikováno v:
Thorax. 73:451-458
BackgroundAntibiotic treatment for pulmonary symptoms in preschool children with cystic fibrosis (CF) varies among clinicians. The lung clearance index (LCI) is sensitive to early CF lung disease, but its utility to monitor pulmonary exacerbations in
Autor:
Sonya L. Heltshe, Amalia Magaret, Bonnie W. Ramsey, M. Warden, George Z. Retsch-Bogart, Nicole Mayer-Hamblett, Noah Simon
Publikováno v:
Journal of Cystic Fibrosis. 20:S24