Zobrazeno 1 - 10
of 37
pro vyhledávání: '"George Yerganian"'
Autor:
Athena Yerganian, Robert N. O'Meally, Michael A. Bowen, Venkata Gayatri Dhara, Kelley M. Heffner, Swetha Kumar, Natalia I. Majewska, Robert Cole, George Yerganian, Michael J. Betenbaugh, Deniz Baycin Hizal, Diane Hatton, Jie Zhu
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Chinese hamster ovary (CHO) cells are the predominant production vehicle for biotherapeutics. Quantitative proteomics data were obtained from two CHO cell lines (CHO-S and CHO DG44) and compared with seven Chinese hamster (Cricetulus griseus) tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7911ff1513b39ed6a431d76914b64e
https://pubmed.ncbi.nlm.nih.gov/32985598
https://pubmed.ncbi.nlm.nih.gov/32985598
Autor:
Robert N. O'Meally, Michael A. Bowen, Michael J. Betenbaugh, Amit Kumar, Özge Can, Herren Wu, George Yerganian, Deniz Baycin Hizal, Robert Cole, Kelley M. Heffner, Raghothama Chaerkady
Publikováno v:
Journal of proteome research. 16(10)
Chinese hamster ovary cells represent the dominant host for therapeutic recombinant protein production. However, few large-scale data sets have been generated to characterize this host organism and derived CHO cell lines at the proteomics level. Cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c382406c114c24eced65a589a09497c
https://pubmed.ncbi.nlm.nih.gov/28876938
https://pubmed.ncbi.nlm.nih.gov/28876938
Publikováno v:
Cancer Genetics and Cytogenetics. 180:89-99
Several researchers, including us, have recently proposed that specific karyotypes, rather than specific mutations, generate the "biochemical individuality" of cancers, defined by individual growth rates, metabolisms, drug-resistances, metastases and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a215209266ddea53cd2077665c90409
https://doi.org/10.1016/j.cancergencyto.2007.10.006
https://doi.org/10.1016/j.cancergencyto.2007.10.006
Publikováno v:
Proceedings of the National Academy of Sciences. 99:6778-6783
Aneuploidy is ubiquitous in cancer, and its phenotypes are inevitably dominant and abnormal. In view of these facts we recently proposed that aneuploidy is sufficient for carcinogenesis generating cancer-specific aneusomies via a chain reaction of au
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43b202db9677b852eac49f8c088e812
https://doi.org/10.1073/pnas.251670699
https://doi.org/10.1073/pnas.251670699
Autor:
Ruhong Li, A. Willer, Ruediger Hehlmann, George Yerganian, Peter H. Duesberg, Charlotte Rausch, David Rasnick, Alwin Kraemer
Publikováno v:
Technological and Medical Implications of Metabolic Control Analysis ISBN: 9780792361893
Despite over loo years of cancer research, including huge investments in the last decades to find cancer-specific mutations, the genetic causes of most cancers are still unclear. Over too cancer-specific mutations have been identified (Bishop, 1995;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7c34691d892a037838637b51c9d9445
https://doi.org/10.1007/978-94-011-4072-0_9
https://doi.org/10.1007/978-94-011-4072-0_9
Autor:
Peter H. Duesberg, Charlotte Rausch, Ruhong Li, Ruediger Hehlmann, A. Willer, George Yerganian, Alwin Kraemer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 94(26)
Aneuploidy or chromosome imbalance is the most massive genetic abnormality of cancer cells. It used to be considered the cause of cancer when it was discovered more than 100 years ago. Since the discovery of the gene, the aneuploidy hypothesis has lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ec8a92cc672ff3b6b82d945a48bcbd
https://pubmed.ncbi.nlm.nih.gov/9405643
https://pubmed.ncbi.nlm.nih.gov/9405643
Autor:
Gerard J. McGarrity, Mihir R. Banerjee, Richard G. Ham, Robert S. Lasher, Edwin H. Lennette, Arthur McIntosh, Paul Moorhead, Toshio Murashige, Leonard R. Murrell, Monroe M. Vincent, George Yerganian
Publikováno v:
In Vitro. 14:317-331
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f749aa2ae1db0087d7f2e1737188a1d
https://doi.org/10.1007/bf02616085
https://doi.org/10.1007/bf02616085
Autor:
Vincent J. Cristofalo, Robert T. Dell'Orco, Stephen D. Hauschka, Holger Hoehn, George M. Martin, Gerald J. McGarrity, Toshio Murashige, Leonard R. Murrell, Keith R. Porter, Monroe M. Vincent, Judith H. Willis, George Yerganian
Publikováno v:
In Vitro. 15:149-165
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8fb0033a0463c6c2552a19991d9c152
https://doi.org/10.1007/bf02616159
https://doi.org/10.1007/bf02616159
Autor:
Robert Dell'Orco, Nelly Auersperg, Vincent Cristofalo, Leonard Keay, Gerard McGarrity, Toshio Murashige, Leonard Murrell, Keith Porter, Judith Willis, George Yerganian
Publikováno v:
In Vitro. 16:189-202
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f49f0fe725c351854f79df9c1ceabec
https://doi.org/10.1007/bf02616148
https://doi.org/10.1007/bf02616148
Publikováno v:
Immunogenetics. 5:33-41
An exceptional (C57BL/6 × BALB/c)F1 male mouse, from an X-irradiated father, and lacking the H-Y (“male”) antigen, on the basis of skin-graft testing, was found. Conventional serological tests for H-Y antigen, however, were positive. His karyoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61f2522b37c8f0556fcad5d4d1110593
https://doi.org/10.1007/bf01570461
https://doi.org/10.1007/bf01570461