Zobrazeno 1 - 10
of 215
pro vyhledávání: '"George Wu"'
Autor:
Aude I. Segaliny, Jayapriya Jayaraman, Xiaoming Chen, Jonathan Chong, Ryan Luxon, Audrey Fung, Qiwei Fu, Xianzhi Jiang, Rodrigo Rivera, Xiaoya Ma, Ci Ren, Jan Zimak, Per Niklas Hedde, Yonglei Shang, George Wu, Weian Zhao
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
A single-cell based bispecific antibody (BsAb) discovery pipeline, based on a microfluidics droplets generation and sorting systems, has the potential to speed up the discovery and development of functional antibodies such as BsAb therapeutics.
Externí odkaz:
https://doaj.org/article/7a14b50910074c84bb0bfc0a503c1bb8
Autor:
Anna S. Lok, Fabien Zoulim, Geoffrey Dusheiko, Henry L.Y. Chan, Maria Buti, Marc G. Ghany, Anuj Gaggar, Jenny C. Yang, George Wu, John F. Flaherty, G. Mani Subramanian, Stephen Locarnini, Patrick Marcellin
Publikováno v:
Hepatology Communications, Vol 4, Iss 1, Pp 8-20 (2020)
In patients with chronic hepatitis B (CHB), loss of hepatitis B surface antigen (HBsAg) is considered a functional cure. However, HBsAg loss is uncommon with existing therapies, and predictive factors associated with HBsAg seroreversion are unknown.
Externí odkaz:
https://doaj.org/article/9554e258943144788e5c32360057cbb9
Autor:
S. Daisy Kosa, Amiram Gafni, Andrew A. House, JulieAnn Lawrence, Louise Moist, Bharat Nathoo, Paul Tam, Alicia Sarabia, Lehana Thabane, George Wu, Charmaine E. Lok
Publikováno v:
Kidney International Reports, Vol 2, Iss 2, Pp 228-238 (2017)
We developed the Hemodialysis Infection Prevention Protocols Ontario—Shower Technique (HIPPO-ST) to permit hemodialysis (HD) patients with central venous catheters (catheters) to shower without additional infection risk. Our primary objective was t
Externí odkaz:
https://doaj.org/article/17f99dd09462467e9bfc7d353fe3b11e
Autor:
Ondrej Podlaha, George Wu, Bryan Downie, Raghuraman Ramamurthy, Anuj Gaggar, Mani Subramanian, Zhishen Ye, Zhaoshi Jiang
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220376 (2019)
Hepatitis B infection is a world-wide public health burden causing serious liver complications. Previous studies suggest that hepatitis B integration into the human genome plays a crucial role in triggering oncogenic process and may also constitutive
Externí odkaz:
https://doaj.org/article/88c92b48a1ba4cd9ab5ca1e561d030e0
Autor:
Robert P Pauly, Paul Komenda, Christopher T Chan, Michael Copland, Azim Gangji, David Hirsch, Robert Lindsay, Martin MacKinnon, Jennifer M MacRae, Philip McFarlane, Gihad Nesrallah, Andreas Pierratos, Martin Plaisance, Frances Reintjes, Jean-Philippe Rioux, John Shik, Andrew Steele, Rod Stryker, George Wu, Deborah L Zimmerman
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 1 (2014)
Background: Over 40% of patients with end stage renal disease in the United States were treated with home hemodialysis (HHD) in the early 1970's. However, this number declined rapidly over the ensuing decades so that the overwhelming majority of pati
Externí odkaz:
https://doaj.org/article/d65e9118787145ab8b7ad3ed4b89a6d0
Autor:
Robert H Newman, Jianfei Hu, Hee‐Sool Rho, Zhi Xie, Crystal Woodard, John Neiswinger, Christopher Cooper, Matthew Shirley, Hillary M Clark, Shaohui Hu, Woochang Hwang, Jun Seop Jeong, George Wu, Jimmy Lin, Xinxin Gao, Qiang Ni, Renu Goel, Shuli Xia, Hongkai Ji, Kevin N Dalby, Morris J Birnbaum, Philip A Cole, Stefan Knapp, Alexey G Ryazanov, Donald J Zack, Seth Blackshaw, Tony Pawson, Anne‐Claude Gingras, Stephen Desiderio, Akhilesh Pandey, Benjamin E Turk, Jin Zhang, Heng Zhu, Jiang Qian
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp n/a-n/a (2013)
The landscape of human phosphorylation networks has not been systematically explored, representing vast, unchartered territories within cellular signaling networks. Although a large number of in vivo phosphorylated residues have been identified by ma
Externí odkaz:
https://doaj.org/article/6886196250374d4893d1b1be6feccd1e
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46521 (2012)
Understanding gene regulation is crucial to dissect the molecular basis of human development and disease. Previous studies on transcription regulatory networks often focused on their static properties. Here we used retinal development as a model syst
Externí odkaz:
https://doaj.org/article/c3fcba613b76477086ba5086aee603c8
Autor:
Hongkai Ji, George Wu, Xiangcan Zhan, Alexandra Nolan, Cheryl Koh, Angelo De Marzo, Hoang Mai Doan, Jinshui Fan, Christopher Cheadle, Mohammad Fallahi, John L Cleveland, Chi V Dang, Karen I Zeller
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26057 (2011)
The functions of key oncogenic transcription factors independent of context have not been fully delineated despite our richer understanding of the genetic alterations in human cancers. The MYC oncogene, which produces the Myc transcription factor, is
Externí odkaz:
https://doaj.org/article/382795415c7445428a36108b48826f40
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14484 (2010)
Germ-line mutations of the breast cancer susceptibility gene-1 (BRCA1) increase the susceptibility to tumorigenesis. The function of BRCA1 is to regulate critical cellular processes, including cell cycle progression, genomic integrity, and apoptosis.
Externí odkaz:
https://doaj.org/article/38bc13f7f40443eb9020b336f5f5858b
Autor:
Rajneesh, Chellappan Praveen, Hsieh, Tsung-Hsun, Chen, Hung-Chou, Liou, Jian-Chiun, Lin, Bor-Shing, George Wu, Chun-Wei, Lai, Chien-Hung, Peng, Chih-Wei
Publikováno v:
In Journal of the Formosan Medical Association March 2023 122(3):239-248