Zobrazeno 1 - 6
of 6
pro vyhledávání: '"George W P, Madders"'
Autor:
Nathan C. Denham, Charles M. Pearman, George W. P. Madders, Charlotte E. R. Smith, Andrew W. Trafford, Katharine M. Dibb
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
BackgroundLarge animal models play an important role in our understanding of the pathophysiology of atrial fibrillation (AF). Our aim was to determine whether prospectively collected baseline variables could predict the development of sustained AF in
Externí odkaz:
https://doaj.org/article/9b71963249ce40c8b1e5a1e1a29a2c65
Autor:
David C. Hutchings, George W. P. Madders, Barbara C. Niort, Elizabeth F. Bode, Caitlin A. Waddell, Lori S. Woods, Katharine M. Dibb, David A. Eisner, Andrew W. Trafford
Publikováno v:
Hutchings, D, Madders, G, Niort, B, Bode, E, Waddell, C, Woods, L, Dibb, K, Eisner, D & Trafford, A 2022, ' Interaction of background Ca2+ influx, sarcoplasmic reticulum threshold and heart failure in determining propensity for Ca2+ waves in sheep heart ', JOURNAL OF PHYSIOLOGY-LONDON . https://doi.org/10.1113/JP282168
Key pointsHeart failure is a pro-arrhythmic state and arrhythmias are a major cause of death. At the cellular level, Ca2+ waves resulting in delayed after-depolarisations are a key trigger of arrhythmias. Ca2+ waves arise when the sarcoplasmic reticu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9002a54cd6ba1eab318aba7f54cc61
https://doi.org/10.1113/jp282168
https://doi.org/10.1113/jp282168
Autor:
Nathan C. Denham, Charles M. Pearman, Jessica L. Caldwell, George W. P. Madders, David A. Eisner, Andrew W. Trafford, Katharine M. Dibb
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Atrial fibrillation (AF) is commonly associated with heart failure. A bidirectional relationship exists between the two—AF exacerbates heart failure causing a significant increase in heart failure symptoms, admissions to hospital and cardiovascular
Externí odkaz:
https://doaj.org/article/64909765f54e44ed91259196e8f432e2
Autor:
Michael Lawless, Jessica L. Caldwell, Emma J. Radcliffe, Charlotte E. R. Smith, George W. P. Madders, David C. Hutchings, Lori S. Woods, Stephanie J. Church, Richard D. Unwin, Graeme J. Kirkwood, Lorenz K. Becker, Charles M. Pearman, Rebecca F. Taylor, David A. Eisner, Katharine M. Dibb, Andrew. W. Trafford
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Heart failure (HF) is characterized by poor survival, a loss of catecholamine reserve and cellular structural remodeling in the form of disorganization and loss of the transverse tubule network. Indeed, survival rates for HF are worse than many commo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::39b864b136f1cfa983f35c432c563617
http://link.springer.com/article/10.1038/s41598-019-42592-1
http://link.springer.com/article/10.1038/s41598-019-42592-1
Autor:
Charles M, Pearman, George W P, Madders, Emma J, Radcliffe, Graeme J, Kirkwood, Michael, Lawless, Amy, Watkins, Charlotte E R, Smith, Andrew W, Trafford, David A, Eisner, Katharine M, Dibb
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Atrial fibrillation (AF) is common in the elderly, but rare in the young; however, the changes that occur with age that promote AF are not fully understood. Action potential (AP) alternans may be involved in the initiation of AF. Using a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e6a65952f763abbce73ef3a1317be405
https://pubmed.ncbi.nlm.nih.gov/31795825
https://pubmed.ncbi.nlm.nih.gov/31795825
Autor:
Michael, Lawless, Jessica L, Caldwell, Emma J, Radcliffe, Charlotte E R, Smith, George W P, Madders, David C, Hutchings, Lori S, Woods, Stephanie J, Church, Richard D, Unwin, Graeme J, Kirkwood, Lorenz K, Becker, Charles M, Pearman, Rebecca F, Taylor, David A, Eisner, Katharine M, Dibb, Andrew W, Trafford
Publikováno v:
Scientific Reports
Heart failure (HF) is characterized by poor survival, a loss of catecholamine reserve and cellular structural remodeling in the form of disorganization and loss of the transverse tubule network. Indeed, survival rates for HF are worse than many commo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b2ad1e5c3b54bfb9b859418c4d0a096
https://pubmed.ncbi.nlm.nih.gov/31043634
https://pubmed.ncbi.nlm.nih.gov/31043634