Zobrazeno 1 - 5
of 5
pro vyhledávání: '"George Tweet"'
Autor:
Konrad Buscher, Erik Ehinger, Pritha Gupta, Akula Bala Pramod, Dennis Wolf, George Tweet, Calvin Pan, Charles D. Mills, Aldons J. Lusis, Klaus Ley
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
The inter-individual variation of the immune system broadly impacts pathophysiology. Here, the authors use the hybrid mouse diversity panel as a surrogate for human natural immune variation and derive a macrophages gene signature robustly correlating
Externí odkaz:
https://doaj.org/article/1fc27041918b48b8a2944c3034860cf1
Autor:
Marcus Altfeld, R. Keith Reeves, Kyle Kroll, George Tweet, Taylor Yoder, Sho K. Sugawara, Paul A. Goepfert, Haley L. Dugan, Scott Smith, Adam Grundhoff, Olivier Lucar, Stephanie Jost, Joshua Ghofrani, Alexandra Werner, Phillip J. Tomezsko, Michaela Müller-Trutwin, Rhianna Jones
For over a decade, multiple studies have disputed the notion of natural killer (NK) cells as purely innate lymphocytes by demonstrating that they are capable of putative antigen-specific immunological memory against multiple infectious agents includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50b311c059cd5b89758b793c7655ad3f
https://doi.org/10.1101/2020.11.09.374348
https://doi.org/10.1101/2020.11.09.374348
Autor:
Pritha P. Gupta, Aldons J. Lusis, Akula Bala Pramod, Konrad Buscher, George Tweet, Dennis Wolf, Klaus Ley, Erik Ehinger, Calvin Pan, Charles D. Mills
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Although mouse models exist for many immune-based diseases, the clinical translation remains challenging. Most basic and translational studies utilize only a single inbred mouse strain. However, basal and diseased immune states in humans show vast in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b368ff9d9d7820fcb8124f478cd57fa8
https://doi.org/10.1038/ncomms16041
https://doi.org/10.1038/ncomms16041
Autor:
Asaf Madi, Elaine O’Loughlin, Anna Worthmann, Oleg Butovsky, Lien Beckers, Tsuneya Ikezu, Frank L. Heppner, Kristin Hartmann, Vladimir Litvak, Mar Gacias, Markus Glatzel, Zain Fanek, Zachary Humulock, Howard L. Weiner, Susanne Krasemann, Joerg Heeren, Jordi Ochando, Zhiping Weng, Ron Cialic, Christian Haass, Yang Xu, Narghes Calcagno, David M. Holtzman, Tobias Zrzavy, Bogdan Budnik, Cynthia A. Lemere, George Tweet, Hans Lassmann, Scott T. Smith, Hao Chen, Caroline Baufeld, Rachid El Fatimy, David J. Greco, Charlotte Madore, Fargol Mazaheri, Emily C. Tjon, Patricia Conde-Sanroman, Jason D. Ulrich
Publikováno v:
Immunity 47(3), 566-581.e9 (2017). doi:10.1016/j.immuni.2017.08.008
Microglia play a pivotal role in the maintenance of brain homeostasis but lose homeostatic function during neurodegenerative disorders. We identified a specific apolipoprotein E (APOE)-dependent molecular signature in microglia from models of amyotro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1c04d37b48c4a61a63dc78d139d1b0
https://pub.dzne.de/record/139513
https://pub.dzne.de/record/139513
Autor:
Robert Tacke, Grzegorz Chodaczek, Shahram Salek-Ardakani, Helena Shaked, Amit Bar-Or, Minna U. Kaikkonen, Catherine C. Hedrick, Susan Togher, George Tweet, Alp Bugra Basat, Ayman Rezk, Christopher K. Glass, Graham D. Thomas, Amy Blatchley, Richard N. Hanna, Zbigniew Mikulski, Hozefa S. Bandukwala, Martin Darvas, Sonia Lai-Wing-Sun, Jacqueline Miller, Iftach Shaked, Heba Nowyhed
Publikováno v:
Nature immunology. 16(12)
The molecular mechanisms that link the sympathetic stress response and inflammation remain obscure. Here we found that the transcription factor Nr4a1 regulated the production of norepinephrine (NE) in macrophages and thereby limited experimental auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07d701b77799e742e6c41f7bdaee9d6
https://pubmed.ncbi.nlm.nih.gov/26580501
https://pubmed.ncbi.nlm.nih.gov/26580501